Inhibidores de ciclooxigenasa (COX)
Cyclooxygenase (COX) inhibitors are a class of compounds that inhibit the activity of COX enzymes, which play a critical role in the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. In the field of neuroscience, COX inhibitors are extensively studied for their potential to alleviate neuroinflammation, a key factor in the progression of various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By blocking COX activity, these inhibitors may help reduce inflammation in the brain, thereby protecting neurons from damage and slowing disease progression. At CymitQuimica, we offer a wide range of high-quality COX inhibitors to support your research in neuroinflammation, pain management, and the study of neurodegenerative disorders.
Se han encontrado 562 productos de "Inhibidores de ciclooxigenasa (COX)"
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Deracoxib
CAS:<p>Deracoxib (SC 46) is a selective COX-2 inhibitor, non-steroidal, non-narcotic anti-inflammatory drug with an IC50 of 70-150 μM for osteosarcoma cells.</p>Fórmula:C17H14F3N3O3SPureza:98.94% - 99.81%Forma y color:SolidPeso molecular:397.37Guaiacol
CAS:<p>Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.</p>Fórmula:C7H8O2Pureza:99.95%Forma y color:Colourless To Pale Yellow Solid CrystallinePeso molecular:124.14Ketorolac tromethamine salt
CAS:Fórmula:C19H24N2O6Pureza:98%Forma y color:SolidPeso molecular:376.4037Metamizole sodium hydrate
CAS:<p>Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).</p>Fórmula:C13H18N3NaO5SPureza:99.69% - 99.89%Forma y color:White Or Light Yellow Crystalline Powder Odorless Tiny BitterPeso molecular:351.36(R)-Naproxen
CAS:<p>(R)-Naproxen: anti-inflammatory with antipyretic and analgesic effects; treats gout, dysmenorrhea, rheumatoid arthritis.</p>Fórmula:C14H14O3Pureza:99.62% - 99.94%Forma y color:SolidPeso molecular:230.262,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-
CAS:Fórmula:C18H15ClN2O2SPureza:98%Forma y color:SolidPeso molecular:358.8419Ref: IN-DA002878
1g80,00€5g155,00€10g297,00€1kgA consultar100g558,00€10mg33,00€500gA consultar100mg36,00€250mg44,00€Catechin
CAS:<p>Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.</p>Fórmula:C15H14O6Pureza:97.34% - 99.82%Forma y color:SolidPeso molecular:290.27Tebufelone
CAS:<p>Tebufelone is a potent NSAID, inhibits CO, has anti-inflammatory and analgesic properties, and blocks lipoxygenase products (IC50 ~20-22 microM).</p>Fórmula:C20H28O2Pureza:99.32%Forma y color:SolidPeso molecular:300.442-O-Sinapoyl makisterone A
<p>Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectively</p>Fórmula:C39H56O11Pureza:98%Forma y color:SolidPeso molecular:700.8615-LOX-IN-2
<p>15-LOX-IN-2 (Compound 2a) is an orally active inhibitor of COX-2/15-LOX and a partial agonist of PPARγ. It exhibits anti-inflammatory activity by inhibiting levels of 20-HETE, IL-1β, and TNF-α in LPS-treated RAW 264.7 cells. Additionally, it significantly enhances glucose uptake without the presence of insulin and is applicable in metabolic disease research.</p>Forma y color:Odour SolidCOX-1/2-IN-5
<p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>Fórmula:C21H22N2O5SPureza:98%Forma y color:SolidPeso molecular:414.474-ACETAMIDOANTIPYRINE
CAS:<p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C13H15N3O2Forma y color:SolidPeso molecular:245.28COX-2-IN-33
<p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>Fórmula:C20H13ClF3N5O4Pureza:98%Forma y color:SolidPeso molecular:479.8Pemedolac
CAS:<p>Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.</p>Fórmula:C22H23NO3Pureza:>99.99%Forma y color:SolidPeso molecular:349.42NF157
CAS:<p>NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.</p>Fórmula:C49H28F2N6Na6O23S6Pureza:98%Forma y color:SolidPeso molecular:1437.1COX-1/2-IN-4
<p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>Fórmula:C22H24N2O2SPureza:98%Forma y color:SolidPeso molecular:380.5Ketoprofen lysine salt
CAS:<p>Ketoprofen lysine salt is a lysine salt of ketoprofen, a Non-Steroidal Anti-Inflammatory Drug</p>Fórmula:C22H28N2O5Forma y color:SolidPeso molecular:400.48SARS-CoV-2 Mpro-IN-41
<p>SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.</p>Fórmula:C27H23ClN4O3SForma y color:SolidPeso molecular:518.11794Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Fórmula:C24H22N2O4SPureza:98%Forma y color:SolidPeso molecular:434.51
![2,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA002878.webp&w=3840&q=75)
