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Inhibidores de ciclooxigenasa (COX)

Inhibidores de ciclooxigenasa (COX)

Cyclooxygenase (COX) inhibitors are a class of compounds that inhibit the activity of COX enzymes, which play a critical role in the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. In the field of neuroscience, COX inhibitors are extensively studied for their potential to alleviate neuroinflammation, a key factor in the progression of various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By blocking COX activity, these inhibitors may help reduce inflammation in the brain, thereby protecting neurons from damage and slowing disease progression. At CymitQuimica, we offer a wide range of high-quality COX inhibitors to support your research in neuroinflammation, pain management, and the study of neurodegenerative disorders.

Se han encontrado 562 productos de "Inhibidores de ciclooxigenasa (COX)"

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  • Nepafenac-d5

    CAS:
    <p>Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .</p>
    Fórmula:C15H14N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:259.31
  • AHR-10037

    CAS:
    <p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>
    Fórmula:C15H13ClN2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:288.73
  • Amfenac

    CAS:
    <p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>
    Fórmula:C15H13NO3
    Forma y color:Solid
    Peso molecular:255.27
  • Pelubiprofen

    CAS:
    <p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>
    Fórmula:C16H18O3
    Pureza:99.69%
    Forma y color:Solid
    Peso molecular:258.31
  • COX-2-IN-2

    CAS:
    <p>COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.</p>
    Fórmula:C17H12FN3O2S
    Pureza:97.62%
    Forma y color:Solid
    Peso molecular:341.36
  • COX-2-IN-26

    CAS:
    <p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>
    Fórmula:C23H21N7OS3
    Forma y color:Solid
    Peso molecular:507.65
  • Loxoprofenol-SRS tromethamine

    CAS:
    <p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>
    Fórmula:C19H31NO6
    Forma y color:Solid
    Peso molecular:369.45
  • COX-2-IN-24

    CAS:
    <p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>
    Fórmula:C24H24BrN5O3S2
    Forma y color:Solid
    Peso molecular:574.51
  • COX-2-IN-18

    CAS:
    <p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>
    Fórmula:C18H19N3O3S2
    Forma y color:Solid
    Peso molecular:389.49
  • COX-2-IN-14

    CAS:
    <p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>
    Fórmula:C18H18N4O6
    Forma y color:Solid
    Peso molecular:386.364
  • SC57666

    CAS:
    <p>SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.</p>
    Fórmula:C18H17FO2S
    Pureza:98.83%
    Forma y color:Solid
    Peso molecular:316.39
  • FR-188582

    CAS:
    <p>FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).</p>
    Fórmula:C16H13ClN2O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:332.8
  • Anti-inflammatory agent 56

    CAS:
    <p>Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties by</p>
    Fórmula:C21H15F3N4O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:476.43
  • COX/5-LO-IN-1

    CAS:
    <p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>
    Fórmula:C16H15FN2O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:318.37
  • MK-0703

    CAS:
    <p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>
    Fórmula:C17H22O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:338.42
  • COX-2/15-LOX-IN-1

    CAS:
    <p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>
    Fórmula:C21H21N7S3
    Forma y color:Solid
    Peso molecular:467.63
  • COX-2-IN-17

    CAS:
    <p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>
    Fórmula:C20H23ClN6O2
    Forma y color:Solid
    Peso molecular:414.89
  • COX-2-IN-23

    CAS:
    <p>COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.</p>
    Fórmula:C24H25N5O3S2
    Forma y color:Solid
    Peso molecular:495.62
  • COX-1/2-IN-3

    CAS:
    <p>COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].</p>
    Fórmula:C14H8N2O8
    Forma y color:Solid
    Peso molecular:332.22
  • COX-1/2-IN-1

    CAS:
    <p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>
    Fórmula:C15H10BrClN2O
    Forma y color:Solid
    Peso molecular:349.61