CAMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are specialized compounds that inhibit the activity of CaMK, a critical kinase involved in a range of cellular processes, particularly within the nervous system. CaMK is essential for translating calcium signals into various cellular responses, including synaptic plasticity, memory formation, and gene expression. Dysregulation of CaMK activity is linked to several neurological disorders, making these inhibitors valuable tools in the study of synaptic signaling, learning, and memory. By using CaMK inhibitors, researchers can explore the molecular mechanisms underlying cognitive function and synaptic plasticity. At CymitQuimica, we provide high-quality CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Se han encontrado 66 productos para "CAMK".
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A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22Y-33075 dihydrochloride
CAS:Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Fórmula:C16H18Cl2N4OPureza:98.88% - 99.89%Forma y color:SolidPeso molecular:353.25Ref: TM-T13384L
1mg34,00€5mg66,00€1mL*10mM (DMSO)78,00€10mg102,00€25mg192,00€50mg341,00€100mg510,00€200mg732,00€Elziverine
CAS:Elziverine: oral calmodulin antagonist, inhibits Ca-induced acanthocyte formation, potential for neurological and cognitive disorder treatment.Fórmula:C32H37N3O5Pureza:99.79%Forma y color:SolidPeso molecular:543.65Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Fórmula:C21H26Cl2F3N3SPureza:99.57% - 99.96%Forma y color:SolidPeso molecular:480.43TAT-CN21
TAT-CN21 is a cell-permeable CaMKII inhibitory peptide used to study neuronal excitotoxicity and ischemic injury by blocking CaMKII activity.Fórmula:C169H303N69O43Forma y color:White SolidPeso molecular:3989.65Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine-N-2-chloroethane hydrochloride is a fluphenazine derivative used as a calmodulin probe.Fórmula:C22H27Cl3F3N3SForma y color:SolidPeso molecular:528.89CaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).Fórmula:C54H58Cl2N10O11Pureza:98%Forma y color:SolidPeso molecular:1094CALP2
CAS:CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.Fórmula:C68H104N14O13SPureza:98%Forma y color:SolidPeso molecular:1357.72Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Fórmula:C105H189N31O26SPureza:96.7%Forma y color:SolidPeso molecular:2333.88CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Fórmula:C70H105F3N14O15SForma y color:SolidPeso molecular:1471.72Syntide 2 TFA
Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.Fórmula:C70H123N20F3O20Forma y color:SolidPeso molecular:1621.84MLCK Peptide
CAS:MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Fórmula:C91H156N36O20Forma y color:SolidPeso molecular:2074.44Calmodulin Kinase IINtide, Myristoylated
Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].Fórmula:C156H275N47O43Pureza:98%Forma y color:SolidPeso molecular:3497.14Calmodulin-Dependent Protein Kinase II (281-309)
CAS:Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Fórmula:C146H254N46O39S3Pureza:98%Forma y color:SolidPeso molecular:3374.06Fasciculic acid C
CAS:Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C38H63NO11Pureza:98%Forma y color:SolidPeso molecular:709.91Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Fórmula:C22H27Cl2N3O4Pureza:99.76%Forma y color:SolidPeso molecular:468.37TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Forma y color:Odour SolidBeauverolide Ja
CAS:Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.Fórmula:C35H46N4O5Forma y color:SolidPeso molecular:602.76RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Forma y color:Odour SolidAC3-I, myristoylated
Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).Fórmula:C78H137N21O20Pureza:98%Forma y color:SolidPeso molecular:1689.05Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Fórmula:C231H373N69O70S2Pureza:98%Forma y color:SolidPeso molecular:5301.1CAMKIV Protein, Human, Recombinant (GST)
CAMKIV Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.Forma y color:Lyophilized PowderPeso molecular:79 kDa (predicted); 100 kDa (reducing conditions)A-484954
CAS:A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.Fórmula:C13H15N5O3Pureza:97.47% - 99.86%Forma y color:SolidPeso molecular:289.29Ref: TM-TQ0137
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg137,00€25mg289,00€50mg515,00€100mg733,00€KN-92 hydrochloride
CAS:KN-92 hydrochloride is an inactive derivative of KN-93.Fórmula:C24H26Cl2N2O3SPureza:99.68%Forma y color:White SolidPeso molecular:493.45KN-92
CAS:KN-92 is an inactive analog of the CaM kinase II inhibitor KN 93.Fórmula:C24H25ClN2O3SForma y color:SolidPeso molecular:456.98KN-93
CAS:KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Fórmula:C26H29ClN2O4SPureza:99.56% - 99.95%Forma y color:White SolidPeso molecular:501.04Ref: TM-T2697
1mg54,00€2mg74,00€5mg107,00€1mL*10mM (DMSO)120,00€10mg146,00€25mg289,00€50mg358,00€100mg523,00€Trifluoperazine
CAS:Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Fórmula:C21H24F3N3SPureza:98.3% - 99.46%Forma y color:SolidPeso molecular:407.5NH125
CAS:NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Fórmula:C27H45IN2Pureza:98.60%Forma y color:SolidPeso molecular:524.56Ref: TM-T6605
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg113,00€25mg250,00€50mg430,00€100mg620,00€KN-62
CAS:KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Fórmula:C38H35N5O6S2Pureza:99.80% - >99.99%Forma y color:SolidPeso molecular:721.84Ref: TM-T2694
1mg34,00€2mg49,00€5mg71,00€10mg105,00€1mL*10mM (DMSO)105,00€25mg207,00€50mg404,00€100mg592,00€CaMKII-IN-1
CAS:CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).Fórmula:C29H30ClN5O2SPureza:99.69%Forma y color:SolidPeso molecular:548.1Ref: TM-T14860
1mg50,00€2mg71,00€5mg113,00€1mL*10mM (DMSO)137,00€10mg166,00€25mg334,00€50mg520,00€100mg750,00€lavendustin C
CAS:lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Fórmula:C14H13NO5Pureza:98.06%Forma y color:SolidPeso molecular:275.26Ref: TM-T4185
1mg42,00€2mg55,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€STO-609
CAS:STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.Fórmula:C19H10N2O3Pureza:97.14% - 99.35%Forma y color:SolidPeso molecular:314.29Ref: TM-T3546
1mg39,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg120,00€25mg250,00€50mg400,00€100mg620,00€200mg873,00€CaMKP Inhibitor
CAS:CaMKP Inhibitor can inhibit CaMKP.Fórmula:C10H8NNaO7S2Pureza:99.91% - 99.98%Forma y color:SolidPeso molecular:341.28Ref: TM-T2159
1mg39,00€5mg82,00€1mL*10mM (DMSO)102,00€10mg120,00€25mg227,00€50mg334,00€100mg460,00€500mg1.035,00€Stains-All
CAS:Stains-All is a cationic dye of carbocyanine.Fórmula:C30H27BrN2S2Pureza:98.85% - 99.71%Forma y color:Black SolidPeso molecular:559.58CALP2 acetate(261969-04-4 free base)
CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM.Fórmula:C68H104N14O13SPureza:99.91%Forma y color:White SolidPeso molecular:1357.7Syntide 2 acetate(108334-68-5 free base)
Syntide-2 acetate is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 μM).Fórmula:C70H126N20O20Pureza:99.87%Forma y color:Purple LiquidPeso molecular:1567.85Autocamtide-2-related inhibitory peptide TFA salt
Autocamtide-2-related inhibitory peptide TFA salt(CaM kinase II inhibitor TFA salt) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Fórmula:C66H117F3N22O21Pureza:>99.99%Forma y color:SolidPeso molecular:1611.77Autocamtide-2-related inhibitory peptide
CAS:Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Fórmula:C64H116N22O19Pureza:>99.99%Forma y color:SolidPeso molecular:1497.74Autocamtide 2 TFA(129198-88-5 free base)
Autocamtide 2 TFA, selective CaMKII peptide substrate, used in its activity assay.Fórmula:C67H119F3N22O22Pureza:99.86%Forma y color:SolidPeso molecular:1641.79GSK3i XIII
CAS:GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Fórmula:C18H19N5Pureza:98.87%Forma y color:SolidPeso molecular:305.38Ref: TM-T24111
1mg63,00€5mg114,00€1mL*10mM (DMSO)128,00€10mg172,00€25mg279,00€50mg406,00€100mg572,00€IGS-1.76
CAS:IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.Fórmula:C22H18N2OSPureza:98.18% - 98.56%Forma y color:SolidPeso molecular:358.46L-6355
CAS:L-6355 is an agent of bioactive chemicals.Fórmula:C25H30INO3Forma y color:SolidPeso molecular:519.42W-5 hydrochloride
CAS:W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist.Fórmula:C16H23ClN2O2SPureza:99.35%Forma y color:SolidPeso molecular:342.88A-7 hydrochloride
CAS:A-7 hydrochloride is a calmodulin antagonist and causes alterations in the subpopulation of CD44+CD24- in MDA-MB-231 cells.Fórmula:C20H30Cl2N2O2SPureza:99.38%Forma y color:SolidPeso molecular:433.44Prenylamine lactate
CAS:Prenylamine lactate, an ex-angina drug, depletes heart catecholamines and blocks calcium channels.Fórmula:C27H33NO3Pureza:98%Forma y color:SolidPeso molecular:419.56Zaldaride maleate
CAS:Zaldaride maleate blocks Ca2+, Na+, K+ currents, and nAChR; inhibits CaM cAMP PDE (IC50: 3.3 nM) and estrogen signaling.Fórmula:C30H32N4O6Pureza:98%Forma y color:SolidPeso molecular:544.6TX-1123
CAS:TX-1123: PTK/COX inhibitor, Src/eEF2-K/PKA/EGFR-K/PKC targeted, IC50 of 1.16μM(COX2), 15.7μM(COX1), low mitochondrial toxicity.Fórmula:C20H24O3Forma y color:SolidPeso molecular:312.4CV-159
CAS:CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action.Fórmula:C31H34N4O7Pureza:98%Forma y color:SolidPeso molecular:574.62CK59
CAS:CK59 inhibits CaMKII and several voltage-gated calcium channels, with an IC50 of ~50 μM.Fórmula:C21H37N7O3Pureza:98%Forma y color:SolidPeso molecular:435.56Bisindolylmaleimide VII
CAS:Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.Fórmula:C27H27N5O2Forma y color:SolidPeso molecular:453.54
