CymitQuimica logo
GluR

GluR

Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.

Se han encontrado 255 productos de "GluR"

Ordenar por

Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
productos por página.
  • (±)-LY367385

    CAS:
    <p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>
    Fórmula:C10H11NO4
    Forma y color:Solid
    Peso molecular:209.201
  • MPPG

    CAS:
    <p>MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).</p>
    Fórmula:C9H12NO5P
    Forma y color:Solid
    Peso molecular:245.171
  • KRP-199 sodium


    <p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>
    Fórmula:C22H12F3N5Na2O7
    Pureza:97.27%
    Forma y color:Soild
    Peso molecular:561.33
  • LY3027788

    CAS:
    <p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>
    Fórmula:C25H31F2NO11S
    Forma y color:Solid
    Peso molecular:591.58
  • (S,S)-BMS-984923

    CAS:
    <p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 &gt;1μM; less active than its potent counterpart.</p>
    Fórmula:C22H15ClN2O2
    Forma y color:Solid
    Peso molecular:374.82
  • STX-107

    CAS:
    <p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>
    Fórmula:C18H10FN3S
    Pureza:99.17%
    Forma y color:Solid
    Peso molecular:319.36
  • JF-NP-26


    <p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>
    Forma y color:Solid
  • LY2812223

    CAS:
    <p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>
    Fórmula:C10H12N4O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:284.29
  • MGS0274

    CAS:
    <p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>
    Fórmula:C21H32FNO7
    Forma y color:Solid
    Peso molecular:429.485
  • ML353


    <p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>
    Fórmula:C19H15FN2O
    Pureza:99.98% - 99.98%
    Forma y color:Soild
    Peso molecular:306.33
  • 1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-

    CAS:
    <p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>
    Fórmula:C10H12N2O2S
    Pureza:99.96%
    Forma y color:Soild
    Peso molecular:224.28
  • LY3020371

    CAS:
    <p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>
    Fórmula:C15H15F2NO5S
    Forma y color:Solid
    Peso molecular:359.34
  • LY3027788 hydrochloride

    CAS:
    <p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>
    Fórmula:C25H32ClF2NO11S
    Forma y color:Solid
    Peso molecular:628.03
  • (S)-3,4-DCPG

    CAS:
    <p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>
    Fórmula:C10H9NO6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:239.18
  • MGS0028

    CAS:
    <p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>
    Fórmula:C8H8FNO5
    Forma y color:Solid
    Peso molecular:217.15
  • L-AP3

    CAS:
    <p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>
    Fórmula:C3H8NO5P
    Forma y color:White Hygroscopic Solid
    Peso molecular:169.073
  • (S)-3,4-DCPG HCl


    <p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>
    Fórmula:C10H10ClNO6
    Pureza:99.53% - 99.9%
    Forma y color:Soild
    Peso molecular:275.64
  • NS-102

    CAS:
    <p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>
    Fórmula:C12H11N3O4
    Pureza:98.48% - 98.95%
    Forma y color:Solid
    Peso molecular:261.23
  • VU0422288

    CAS:
    <p>VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.</p>
    Fórmula:C17H11Cl2N3O2
    Pureza:95.48%
    Forma y color:Solid
    Peso molecular:360.19
  • VU0364770 hydrochloride

    CAS:
    <p>VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).</p>
    Fórmula:C12H10Cl2N2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:269.13