AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 575 productos de "AChR"
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Br-PBTC
CAS:<p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>Fórmula:C14H15BrN2OSForma y color:SolidPeso molecular:339.25β2AR/M-receptor agonist-1
CAS:<p>β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and</p>Fórmula:C43H56BrN3O7Forma y color:SolidPeso molecular:806.82Dexetimide
CAS:<p>Dexetimide, a muscarinic receptor antagonist, treats neuroleptic-induced parkinsonism.</p>Fórmula:C23H26N2O2Forma y color:SolidPeso molecular:362.46Metixene hydrochloride hydrate
CAS:<p>Metixene HCl hydrate is a potential anticholinergic for Parkinson's with IC50 of 55 nM and Ki of 15 nM against muscarine receptors.</p>Fórmula:C20H26ClNOSPureza:99.88%Forma y color:SolidPeso molecular:363.95Fipexide hydrochloride
CAS:<p>Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.</p>Fórmula:C20H22Cl2N2O4Forma y color:SolidPeso molecular:425.31NKH477
CAS:<p>NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.</p>Fórmula:C27H44ClNO8Pureza:98% - 98%Forma y color:SolidPeso molecular:546.09Tolterodine
CAS:<p>Tolterodine ((R)-(+)-Tolterodine) is an mACh antagonist used in the treatment of detrusor instability and overactive bladder syndrome.</p>Fórmula:C22H31NOPureza:99.71%Forma y color:White Like Or Light Brown Crystalline PowderPeso molecular:325.49YM-58790 hydrochloride
CAS:<p>YM-58790 is a potent M3 muscarinic receptor antagonist(Ki of 15 nM).</p>Fórmula:C27H32ClN3O2Pureza:98%Forma y color:SolidPeso molecular:466.02Palmatine hydroxide
CAS:<p>Palmatine hydroxide: oral IDO-1 inhibitor (IC50: 3-157μM), targets WNV protease, has anti-cancer/viral and neuroprotective properties.</p>Fórmula:C21H23NO5Forma y color:SolidPeso molecular:369.41Cevimeline
CAS:<p>Cevimeline: muscarinic agonist, treats dry mouth & Sjögren's, boosts saliva post-cancer radiotherapy.</p>Fórmula:C10H17NOSForma y color:Off-White SolidPeso molecular:199.31Pirmenol hydrochloride
CAS:<p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>Fórmula:C22H31ClN2OForma y color:SolidPeso molecular:374.95Varenicline Hydrochloride
CAS:<p>Varenicline Hydrochloride (CP 526555) is an orally active partial agonist of the α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM).</p>Fórmula:C13H14ClN3Pureza:99.854%Forma y color:SolidPeso molecular:247.72Cevimeline hydrochloride
CAS:<p>Cevimeline HCl is a muscarinic agonist enhancing salivary and sweat gland secretion.</p>Fórmula:C10H18ClOSForma y color:SolidPeso molecular:235.77Glycerophosphoinositol choline
CAS:<p>Glycerophosphoinositol choline is the salt of choline and glycerophosphoinositol.</p>Fórmula:C14H32NO12PForma y color:SolidPeso molecular:437.38Ispronicline
CAS:<p>Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive</p>Fórmula:C14H22N2OPureza:97.70% - 99.16%Forma y color:SolidPeso molecular:234.34Sabcomeline hydrochloride
CAS:<p>Sabcomeline is a selective M1 receptor partial agonist.</p>Fórmula:C10H16ClN3OForma y color:SolidPeso molecular:229.71(±)-Darifenacin
CAS:<p>(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.</p>Fórmula:C28H30N2O2Forma y color:SolidPeso molecular:426.55VU0467485
CAS:<p>VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.</p>Fórmula:C17H17FN4O2SPureza:98%Forma y color:SolidPeso molecular:360.41Clorprenaline
CAS:<p>Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.</p>Fórmula:C11H16ClNOPureza:98.9%Forma y color:SolidPeso molecular:213.7ABT-107
CAS:<p>ABT-107: α7 neuronal receptor agonist; protects rats' brains from 6-OHDA-induced damage.</p>Fórmula:C19H20N4OForma y color:SolidPeso molecular:320.396
