AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 575 productos de "AChR"
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Encenicline
CAS:<p>Encenicline (EVP-6124), a selective α7 nAChRs agonist, targets cognitive impairment in schizophrenia and Alzheimer's.</p>Fórmula:C16H17ClN2OSPureza:99.20%Forma y color:SolidPeso molecular:320.84Propiverine
CAS:<p>Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.</p>Fórmula:C23H29NO3Forma y color:SolidPeso molecular:367.48JHU37160
CAS:JHU37160 is a DREADD agonist with Ki of 1.9 nM for hM3Dq, 3.6 nM for hM4Di, and EC50 of 18.5 nM (hM3Dq), 0.2 nM (hM4Di) in HEK-293 cell assays.Fórmula:C19H20ClFN4Pureza:99.87%Forma y color:SolidPeso molecular:358.84OXOMEMAZINE
CAS:<p>Oxomemazine: a phenothiazine antihistamine H1-blocker with strong antimuscarinic and selective M1 antagonist properties, used in cough research.</p>Fórmula:C18H22N2O2SPureza:99.58%Forma y color:SolidPeso molecular:330.44Mecamylamine
CAS:<p>Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.</p>Fórmula:C11H21NForma y color:SolidPeso molecular:167.29Methylbenactyzium Bromide
CAS:<p>Methylbenactyzium Bromide (Semulgin) is an anticonvulsant that is the active metabolite of trimethadione.</p>Fórmula:C21H28BrNO3Pureza:99.29%Forma y color:SolidPeso molecular:422.36Solifenacin hydrochloride
CAS:<p>Solifenacin Hcl is a muscarinic receptor antagonist.</p>Fórmula:C23H27ClN2O2Pureza:98%Forma y color:SolidPeso molecular:398.93Donepezil Hydrochloride
CAS:<p>Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).</p>Fórmula:C24H29NO3·HClPureza:99.55% - 99.8%Forma y color:White To Off-White Crystalline SolidPeso molecular:415.96Isopropamide Iodide
CAS:<p>Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.</p>Fórmula:C23H33IN2OPureza:99.67%Forma y color:SolidPeso molecular:480.43SQ22536
CAS:<p>SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.</p>Fórmula:C9H11N5OPureza:99.18%Forma y color:Off-White SolidPeso molecular:205.22ML380
CAS:<p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>Fórmula:C23H25F3N4O3SPureza:99.69%Forma y color:SolidPeso molecular:494.53VU0467154
CAS:<p>VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.</p>Fórmula:C17H15F3N4O3S2Pureza:98.28% - 99.51%Forma y color:SolidPeso molecular:444.45VU0152100
CAS:<p>VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).</p>Fórmula:C18H19N3O2SPureza:99.56%Forma y color:SolidPeso molecular:341.43Ipratropium Bromide
CAS:<p>Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.</p>Fórmula:C20H30BrNO3Pureza:99.92%Forma y color:SolidPeso molecular:412.37VU0119498
CAS:<p>VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.</p>Fórmula:C15H10BrNO2Pureza:97.56%Forma y color:SolidPeso molecular:316.15Succinylcholine Chloride Dihydrate
CAS:<p>Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.</p>Fórmula:C14H30N2O4·2Cl·2H2OPureza:99.87%Forma y color:White SolidPeso molecular:397.34VU10010
CAS:<p>VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.</p>Fórmula:C17H16ClN3OSPureza:99.36%Forma y color:SolidPeso molecular:345.85Procyclidine hydrochloride
CAS:<p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>Fórmula:C19H30ClNOPureza:99.24% - 99.88%Forma y color:Crystals From Petroleum Ether White PowderPeso molecular:323.9Oxotremorine sesquifumarate
CAS:<p>Oxotremorine sesquifumarate is a muscarinic agonist.</p>Fórmula:C12H18N2OC4H4O4Pureza:97.94%Forma y color:SolidPeso molecular:380.39TQS
CAS:<p>TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.</p>Fórmula:C22H20N2O2SPureza:98.56%Forma y color:SolidPeso molecular:376.47
