AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 575 productos de "AChR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
NS9283
CAS:<p>NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.</p>Fórmula:C14H8N4OPureza:99.12%Forma y color:SolidPeso molecular:248.24VU0119498
CAS:<p>VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.</p>Fórmula:C15H10BrNO2Pureza:97.56%Forma y color:SolidPeso molecular:316.15MC-Val-Cit-PABC-PNP
CAS:MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.Fórmula:C35H43N7O11Pureza:97.2% - 98.055%Forma y color:SolidPeso molecular:737.76VU0467154
CAS:<p>VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.</p>Fórmula:C17H15F3N4O3S2Pureza:98.28% - 99.51%Forma y color:SolidPeso molecular:444.45Blarcamesine
CAS:<p>Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.</p>Fórmula:C19H23NOPureza:99.87%Forma y color:SolidPeso molecular:281.39Rivanicline hemioxalate
<p>Rivanicline hemioxalate is a selective α4β2 nicotinic receptor agonist (K i =26 nM), over 1,000x preference to α7 (K i =3.6 μM), with limited side effects.</p>Fórmula:C12H16N2O4Pureza:98%Forma y color:SolidPeso molecular:207.23Pirmenol
CAS:<p>Pirmenol is a new antiarrhythmic drug</p>Fórmula:C22H30N2OPureza:97.24%Forma y color:SolidPeso molecular:338.49PHA 568487
CAS:<p>PHA 568487: α-7 nAChR agonist, rapid brain uptake, lessens oxidative stress & neuroinflammation.</p>Fórmula:C20H24N2O7Forma y color:SolidPeso molecular:404.419PNU-120596
CAS:<p>PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.</p>Fórmula:C13H14ClN3O4Pureza:99.82%Forma y color:SolidPeso molecular:311.72VU 0238429
CAS:<p>VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).</p>Fórmula:C17H12F3NO4Pureza:>99.99%Forma y color:SolidPeso molecular:351.28NS 1738
CAS:<p>NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)</p>Fórmula:C14H9Cl2F3N2O2Pureza:99.11%Forma y color:SolidPeso molecular:365.13MC-Val-Cit-PAB
CAS:<p>MC-Val-Cit-PAB: cathepsin-cleavable ADC linker used in FDA-approved brentuximab vedotin.</p>Fórmula:C28H40N6O7Pureza:98.24%Forma y color:SolidPeso molecular:572.65Nitrobenzylthioinosine
CAS:<p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>Fórmula:C17H17N5O6SPureza:99.69% - 99.74%Forma y color:Off-White SolidPeso molecular:419.419-Ethyladenine
CAS:<p>9-Ethyladenine (6-Amino-9-ethylpurine) is a partially potent APRT (adenine phosphoribosyltransferase) inhibitor [1].</p>Fórmula:C7H9N5Pureza:99.35% - 99.41%Forma y color:SolidPeso molecular:163.18Ipratropium Bromide
CAS:<p>Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.</p>Fórmula:C20H30BrNO3Pureza:99.92%Forma y color:SolidPeso molecular:412.37Umeclidinium bromide
CAS:<p>Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist.</p>Fórmula:C29H34BrNO2Pureza:98.4% - 99.89%Forma y color:SolidPeso molecular:508.49Oxyphencyclimine
CAS:<p>Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.</p>Fórmula:C20H28N2O3Forma y color:SolidPeso molecular:344.45Batefenterol
CAS:<p>Batefenterol (GSK961081) is a muscarinic antagonist and β2-agonist with high affinity (Ki: 1.4/1.3/3.7 nM).</p>Fórmula:C40H42ClN5O7Pureza:97.94% - 98.4%Forma y color:SolidPeso molecular:740.24α-Conotoxin MII acetate
<p>α-Conotoxin MII acetate is a 16-amino acid peptide from the venom of the marine snail Conus magus.</p>Fórmula:C69H107N23O24S4Pureza:94.82% - 97.79%Forma y color:SolidPeso molecular:1770.99Oxyphenonium bromide
CAS:<p>Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.</p>Fórmula:C21H34BrNO3Pureza:98.96%Forma y color:SolidPeso molecular:428.404
