AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 623 productos de "AChR"
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A-424274
CAS:A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.Fórmula:C14H15N3Pureza:98%Forma y color:SolidPeso molecular:225.29Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Fórmula:C31H33NO7Pureza:99.88%Forma y color:SolidPeso molecular:531.6Ref: TM-T13385
2mg35,00€5mg52,00€10mg80,00€25mg135,00€50mg212,00€100mg320,00€200mg447,00€1mL*10mM (DMSO)62,00€PTAC oxalate
CAS:muscarinic receptor ligandFórmula:C14H21N3O4S2Pureza:98%Forma y color:SolidPeso molecular:359.46Muscarine tosylate
CAS:Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].Fórmula:C16H27NO5SForma y color:SolidPeso molecular:345.45AR420626
CAS:AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.Fórmula:C21H18Cl2N2O3Pureza:98.62%Forma y color:SolidPeso molecular:417.29VU 0255035
CAS:<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Forma y color:SolidPeso molecular:432.52Adenylyl cyclase-IN-1
CAS:Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].Fórmula:C9H8N2S3Forma y color:SolidPeso molecular:240.37Tiotropium Bromide hydrate
CAS:Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.Fórmula:C19H24BrNO5S2Pureza:98.44% - 99.41%Forma y color:SolidPeso molecular:490.433-Bromocytisine
CAS:3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).Fórmula:C11H13BrN2OPureza:99.974%Forma y color:SolidPeso molecular:269.14Ref: TM-T10108
1mg90,00€5mg213,00€10mg309,00€25mg520,00€50mg748,00€100mg1.026,00€200mg1.378,00€1mL*10mM (DMSO)188,00€Homatropine hydrochloride
CAS:Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussiveFórmula:C16H22ClNO3Forma y color:SolidPeso molecular:311.8mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Fórmula:C19H22N2O2Forma y color:SolidPeso molecular:310.39Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Fórmula:C17H22BrNOS2Pureza:98%Forma y color:SolidPeso molecular:400.4LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Fórmula:C13H14ClN3O2SPureza:98.78%Forma y color:SolidPeso molecular:311.79LG 50643
CAS:LG 50643 is a muscarinic antagonist.Fórmula:C24H34INO2Pureza:98%Forma y color:SolidPeso molecular:495.44Hydroxy Varenicline
CAS:Hydroxy varenicline, a metabolite of the nicotinic acetylcholine receptor (nAChR) agonist varenicline, functions within the biochemical pathway by interacting with nAChR sites.Fórmula:C13H13N3OForma y color:SolidPeso molecular:227.267Tematropium
CAS:Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.Fórmula:C21H31NO8SPureza:99.89%Forma y color:SolidPeso molecular:457.54Ref: TM-T10732
1mg156,00€5mg376,00€10mg590,00€25mg929,00€50mg1.244,00€100mg1.691,00€200mg2.270,00€1mL*10mM (DMSO)435,00€CHF-6366
CAS:CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.Fórmula:C42H48N6O8Forma y color:SolidPeso molecular:764.87LY593093
CAS:LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.Fórmula:C32H30FN3O2Pureza:98%Forma y color:SolidPeso molecular:507.6VU6007496
CAS:<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Fórmula:C25H27N5O2Forma y color:SolidPeso molecular:429.51WIN 62577
CAS:WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.Fórmula:C29H31N3OForma y color:SolidPeso molecular:437.576
