AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 575 productos de "AChR"
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α-Conotoxin PIA TFA
<p>α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.</p>Fórmula:C81H126F3N27O27S4Pureza:98.81%Forma y color:SolidPeso molecular:2095.3AC1-IN-1
CAS:<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Fórmula:C18H18FN5O2Pureza:99.89%Forma y color:SolidPeso molecular:355.37Lobeline sulfate
CAS:<p>Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.</p>Fórmula:C22H29NO6SPureza:98%Forma y color:White PowderPeso molecular:435.54(R)-Dinotefuran
CAS:<p>(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.</p>Fórmula:C7H14N4O3Forma y color:SolidPeso molecular:202.21Biperiden Hydrochloride
CAS:<p>Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.</p>Fórmula:C21H30ClNOPureza:98%Forma y color:SolidPeso molecular:347.92Bensultap
CAS:<p>Bensultap is an agricultural chemical typically used as a pesticide.</p>Fórmula:C17H21NO4S4Pureza:98%Forma y color:SolidPeso molecular:431.61PF-06827443
<p>PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.</p>Fórmula:C24H24N2O4Forma y color:SolidPeso molecular:404.47nAChR modulator-2
CAS:<p>nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Fórmula:C12H8ClN3O2Forma y color:SolidPeso molecular:261.66Muscarinic toxin 3
CAS:<p>Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57</p>Fórmula:C319H489N89O97S8Pureza:98%Forma y color:SolidPeso molecular:7379.35Mant-GTPγS
CAS:<p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>Fórmula:C18H23N6O14P3SForma y color:SolidPeso molecular:672.39(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:<p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>Fórmula:C22H32ClNO2Forma y color:SolidPeso molecular:377.95Emraclidine
CAS:<p>Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.</p>Fórmula:C20H21F3N4OPureza:99.96%Forma y color:SolidPeso molecular:390.4TIP 39, Tuberoinfundibular Neuropeptide
CAS:<p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>Fórmula:C202H325N61O54SPureza:98%Forma y color:SolidPeso molecular:4504.2nAChR agonist CMPI hydrochloride
CAS:<p>CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.</p>Fórmula:C18H20Cl2N4OForma y color:SolidPeso molecular:379.29trans-Cevimeline hydrochloride
CAS:<p>AF 102A hydrochloride is a biochemical.</p>Fórmula:C10H18ClNOSForma y color:SolidPeso molecular:235.77Muscarine
CAS:<p>Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>Fórmula:C9H20NO2Pureza:98%Forma y color:SolidPeso molecular:174.26TC-2559 difumarate
CAS:<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Fórmula:C20H26N2O9Forma y color:SolidPeso molecular:438.43α-Conotoxin AuIB
CAS:<p>Selective antagonist of α3β4 nicotinic acetylcholine receptors.</p>Fórmula:C65H89N17O21S4Pureza:98%Forma y color:SolidPeso molecular:1572.76Rivanicline 2HCl
<p>Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.</p>Fórmula:C10H16Cl2N2Pureza:99.4%Forma y color:SoildPeso molecular:235.15Small Cardioactive Peptide B (SCPB)
CAS:<p>SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).</p>Fórmula:C52H80N14O11S2Pureza:98%Forma y color:SolidPeso molecular:1141.41
