AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 575 productos de "AChR"
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A-85380 HCl
CAS:<p>A-85380 is an agonist of nicotinic acetylcholine receptor.</p>Fórmula:C9H14Cl2N2OForma y color:SolidPeso molecular:237.13Phenglutarimid
CAS:<p>Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.</p>Fórmula:C17H24N2O2Pureza:98%Forma y color:SolidPeso molecular:288.38Pirenzepine
CAS:<p>Pirenzepine targets M1 mAChR, curbs acid secretion, eases spasms, and has anti-cancer properties.</p>Fórmula:C19H21N5O2Forma y color:SolidPeso molecular:351.4ENS-163 phosphate
CAS:<p>Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.</p>Fórmula:C11H19N2O5PSPureza:98%Forma y color:SolidPeso molecular:322.32TMPH hydrochloride
CAS:<p>neuronal nicotinic ACh receptors (nAChRs) antagonist</p>Fórmula:C16H32ClNO2Pureza:98%Forma y color:SolidPeso molecular:305.889-CP-Ade Mesylate
CAS:<p>9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.</p>Fórmula:C11H17N5O3SPureza:99.81%Forma y color:SolidPeso molecular:299.35Arecaidine but-2-ynyl ester tosylate
CAS:mAChR M2 agonistFórmula:C18H23NO5SPureza:98%Forma y color:SolidPeso molecular:365.44GSK575594A
CAS:<p>GSK575594A is a selective agonist of GPR55.</p>Fórmula:C24H23F2N3O3SForma y color:SolidPeso molecular:471.52(R)-Oxybutynin
CAS:<p>(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.</p>Fórmula:C22H31NO3Forma y color:SolidPeso molecular:357.49AC-42
CAS:<p>AC-42 is an allosteric agonist of M1 muscarinic receptor.</p>Fórmula:C20H31NOForma y color:SolidPeso molecular:301.47α7 nAchR-JAK2-STAT3 agonist 1
CAS:<p>α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).</p>Fórmula:C25H30O6Forma y color:SolidPeso molecular:426.5Ethybenztropine
CAS:<p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>Fórmula:C22H27NOPureza:98%Forma y color:SolidPeso molecular:321.46Anabasine hydrochloride
CAS:<p>neuronal nicotinic ACh receptor partial agonist</p>Fórmula:C10H15ClN2Pureza:98%Forma y color:White To Off-White SolidPeso molecular:198.693Flupyrimin
CAS:<p>Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].</p>Fórmula:C13H9ClF3N3OForma y color:SolidPeso molecular:315.68Adenylyl cyclase type 2 agonist-1
CAS:<p>Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.</p>Fórmula:C27H17BrClNO5Forma y color:SolidPeso molecular:550.78RJR-2403 oxalate
CAS:<p>RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.</p>Fórmula:C14H18N2O4Pureza:98%Forma y color:SolidPeso molecular:278.308Bibn 140
CAS:<p>Bibn 140 is a highly selective M2 antagonist, it is used to treat Alzheimer's disease and other cognitive disorders.</p>Fórmula:C32H44N4O3Pureza:98%Forma y color:SolidPeso molecular:532.72AZD 0328
CAS:<p>AZD 0328 is a nicotinic receptor agonist for α7 neurons.</p>Fórmula:C13H16N2OForma y color:SolidPeso molecular:216.28Nelonicline citrate
CAS:<p>Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.</p>Fórmula:C23H27N3O8SForma y color:SolidPeso molecular:505.54S16961
CAS:<p>S16961 (S169611) is an agonist of nicotinic receptor.</p>Fórmula:C41H71NO6Pureza:99.69%Forma y color:SolidPeso molecular:674.01N-0861 racemate
CAS:<p>N-0861 racemate is the racemate of N-0861.</p>Fórmula:C13H17N5Pureza:98%Forma y color:SolidPeso molecular:243.31Bradanicline
CAS:<p>Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.</p>Fórmula:C22H23N3O2Forma y color:SolidPeso molecular:361.44Afacifenacin
CAS:<p>Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.</p>Fórmula:C27H26F3N3O2Pureza:99.83%Forma y color:SolidPeso molecular:481.51mAChr-in-1
CAS:<p>mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).</p>Fórmula:C23H25IN2O2Pureza:98%Forma y color:SolidPeso molecular:488.364-DAMP
CAS:<p>4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.</p>Fórmula:C21H26INO2Pureza:98%Forma y color:SolidPeso molecular:451.34Asoxime dichloride
CAS:<p>Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.</p>Fórmula:C14H16Cl2N4O3Pureza:99.86%Forma y color:SolidPeso molecular:359.21Tarafenacin D-tartrate
CAS:Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Fórmula:C25H26F4N2O8Pureza:99.86%Forma y color:SolidPeso molecular:558.48Camylofine
CAS:<p>Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.</p>Fórmula:C19H32N2O2·2HClPureza:98%Forma y color:SolidPeso molecular:393.4(Rac)-VU 6008667
CAS:<p>(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.</p>Fórmula:C24H17ClF2N2O2Pureza:99.82%Forma y color:SolidPeso molecular:438.85Pentolinium Tartrate
CAS:<p>Pentolinium Tartrate (Pendine) is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.</p>Fórmula:C15H32N2·2C4H5O6Pureza:98%Forma y color:SolidPeso molecular:538.6AF-DX 384 free base
CAS:<p>AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.</p>Fórmula:C27H38N6O2Pureza:98%Forma y color:SolidPeso molecular:478.63Pozanicline
CAS:<p>Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.</p>Fórmula:C11H16N2OPureza:98%Forma y color:SolidPeso molecular:192.26CB-6673567
CAS:<p>CB-6673567 is a selective inhibitor of adenylyl cyclase.</p>Fórmula:C19H14N4O3Forma y color:SolidPeso molecular:346.34NGX-267
CAS:<p>NGX-267, a muscarinic M1 agonist, is used potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive.</p>Fórmula:C10H18N2OSForma y color:SolidPeso molecular:214.33Dac 5945
CAS:<p>DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.</p>Fórmula:C19H30ClN3OPureza:98%Forma y color:SolidPeso molecular:351.91Hexocyclium metilsulfate
CAS:<p>Hexocyclium metilsulfate has anti-gastric secretory effects in humans.</p>Fórmula:C21H36N2O5SPureza:98%Forma y color:SolidPeso molecular:428.59GS 283
CAS:<p>GS 283 is a Ca(2+) antagonist. GS 283 is also a weak histamine and muscarinic receptor blocker in rat and guinea pig tracheal smooth muscles.</p>Fórmula:C17H17NO3Forma y color:SolidPeso molecular:283.32(R)-VU 6008667
CAS:(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).Fórmula:C24H17ClF2N2O2Forma y color:SolidPeso molecular:438.85Anisodine hydrobromide
CAS:<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Fórmula:C17H22BrNO5Forma y color:White Crystals Or Crystalline PowderPeso molecular:400.27Btm 1042
CAS:<p>Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.</p>Fórmula:C21H26ClN3OSForma y color:SolidPeso molecular:403.97Hyoscyamine hydrobromide
CAS:<p>Hyoscyamine hydrobromide is an agent of anticholinergic.</p>Fórmula:C17H24BrNO3Pureza:98%Forma y color:SolidPeso molecular:370.28Sazetidine A dihydrochloride
CAS:<p>α4β2 nicotinic acetylcholine receptor ligand</p>Fórmula:C15H21ClN2O2Pureza:98%Forma y color:SolidPeso molecular:296.79FR 121196
CAS:<p>FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.</p>Fórmula:C12H16FN3O3SForma y color:SolidPeso molecular:301.34Prifuroline
CAS:<p>Prifuroline is an agent of antiarrhythmic.</p>Fórmula:C14H16N2OPureza:98%Forma y color:SolidPeso molecular:228.29Epibatidine 2HCl
CAS:<p>Epibatidine 2HCl is a potent nicotinic agonist.</p>Fórmula:C11H15Cl3N2Pureza:98%Forma y color:SolidPeso molecular:281.61Flutropium Bromide
CAS:<p>Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.</p>Fórmula:C24H29BrFNO3Pureza:98%Forma y color:SolidPeso molecular:478.39Vesamicol
CAS:Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.Fórmula:C17H25NOPureza:98%Forma y color:SolidPeso molecular:259.39Siltenzepine
CAS:<p>Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.</p>Fórmula:C19H20ClN3O4Pureza:98%Forma y color:SolidPeso molecular:389.83L 858051
CAS:<p>L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.</p>Fórmula:C29H48N2O7Forma y color:SolidPeso molecular:536.7DBO-83
CAS:<p>DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.</p>Fórmula:C10H15Cl3N4Pureza:98%Forma y color:SolidPeso molecular:297.61ADX-10061
CAS:<p>ADX-10061 is a dopamine D1 receptor antagonist.</p>Fórmula:C19H20N2O4Forma y color:SolidPeso molecular:340.37UP202-56
CAS:<p>UP202-56 is an adenosinergic agonist and is an adenosine analog.</p>Fórmula:C33H37N7O4Pureza:98%Forma y color:SolidPeso molecular:595.69JN403
CAS:<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Fórmula:C16H21FN2O2Forma y color:SolidPeso molecular:292.35CB-7921220
CAS:<p>CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.</p>Fórmula:C14H12N2O2Pureza:99.59%Forma y color:SolidPeso molecular:240.26Tebanicline tosylate
CAS:<p>Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.</p>Fórmula:C16H19ClN2O4SPureza:98%Forma y color:SolidPeso molecular:370.85Cimetropium Bromide
CAS:<p>Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.</p>Fórmula:C21H28BrNO4Forma y color:SolidPeso molecular:438.36GP531
CAS:<p>GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.</p>Fórmula:C16H21N5O4Forma y color:SolidPeso molecular:347.37Terodiline hydrochloride
CAS:<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Fórmula:C20H28ClNPureza:98%Forma y color:SolidPeso molecular:317.9YM-46303
CAS:<p>YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in</p>Fórmula:C20H23ClN2O2Pureza:>99.99%Forma y color:SolidPeso molecular:358.86CHF5407
CAS:<p>CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on</p>Fórmula:C27H25BrF4N2O3SPureza:>99.99%Forma y color:SolidPeso molecular:613.46Meseclazone
CAS:<p>Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.</p>Fórmula:C11H10ClNO3Pureza:98%Forma y color:SolidPeso molecular:239.65YM-58790
CAS:<p>YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.</p>Fórmula:C27H31N3O2Pureza:98.59%Forma y color:SoildPeso molecular:429.55Metixene hydrochloride
CAS:<p>Metixene hydrochloride is an anticholinergic antiparkinsonian agent.</p>Fórmula:C20H24ClNSPureza:98%Forma y color:SolidPeso molecular:345.93UB 165 fumarate
CAS:<p>UB 165 fumarate is a nAChR agonist, α4β2 partial, α3β2 full, with a 0.27 nM Ki for [3H]-nicotine in rat brain.</p>Fórmula:C17H19ClN2O4Pureza:99.72%Forma y color:SolidPeso molecular:350.8CDD0102
CAS:<p>CDD0102 is a potent agonist of M1 Muscarinic receptor.</p>Fórmula:C8H12N4OPureza:98%Forma y color:SolidPeso molecular:180.21PQCA
CAS:<p>PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.</p>Fórmula:C22H20N4O3Pureza:99.88%Forma y color:SolidPeso molecular:388.425-Iodo-A-85380 dihydrochloride
CAS:α4β2 and α6β2 nicotinic acetylcholine receptors agonistFórmula:C9H13Cl2IN2OPureza:98%Forma y color:SolidPeso molecular:363.02Dimethyl-W84 (dibromide)
CAS:<p>Dimethyl-W84, selective M2 muscarinic receptor modulator; slows N-methylscopolamine release, EC50=3 nM.</p>Fórmula:C34H48Br2N4O4Forma y color:SolidPeso molecular:736.59LY 2087101
CAS:<p>Allosteric potentiator of α7, α4β2 and α4β4 nAChRs</p>Fórmula:C15H11FN2OS2Pureza:98%Forma y color:SolidPeso molecular:318.39Penehyclidine hydrochloride
CAS:<p>Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.</p>Fórmula:C20H30ClNO2Pureza:99.79%Forma y color:SolidPeso molecular:351.91AR-R 17779 hydrochloride
CAS:<p>AR-R17779 hydrochloride: potent α7 nAChR agonist; K i : 92 nM (α7), 16,000 nM (α4β2); enhances rat cognition; anxiolytic; anti-inflammatory.</p>Fórmula:C9H15ClN2O2Forma y color:SolidPeso molecular:218.68Elucaine
CAS:Elucaine is an antagonist of the muscarinic acetylcholine receptor. It has anti-ulcerative activity.Fórmula:C19H23NO2Pureza:98%Forma y color:SolidPeso molecular:297.39(R,R)-Glycopyrrolate
CAS:<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>Fórmula:C19H28BrNO3Pureza:98%Forma y color:SolidPeso molecular:398.34SIB 1508Y maleate
CAS:<p>neuronal nicotinic ACh receptor agonist</p>Fórmula:C16H18N2O4Pureza:98%Forma y color:SolidPeso molecular:302.33LRE1
CAS:<p>LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor.</p>Fórmula:C12H13ClN4SPureza:>99.99%Forma y color:SolidPeso molecular:280.78Sulfoxaflor
CAS:<p>Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.</p>Fórmula:C10H10F3N3OSPureza:99.56%Forma y color:SolidPeso molecular:277.27Darenzepine
CAS:<p>Darenzepine is a muscarinic receptor inhibitor.</p>Fórmula:C21H21N3O2Pureza:99.87%Forma y color:SolidPeso molecular:347.41Terodiline
CAS:<p>Terodiline is an orally available selective muscarinic M1 receptor and calcium channel antagonist for the study of diseases caused by abnormal bladder function.</p>Fórmula:C20H27NPureza:98.20% - 99.59%Forma y color:SolidPeso molecular:281.44Methacholine bromide
CAS:<p>Methacholine bromide is a potent M3 agonist for diagnosing asthma by identifying bronchial hyperresponsiveness.</p>Fórmula:C8H18BrNO2Forma y color:SolidPeso molecular:240.141Nuvenzepine
CAS:Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.Fórmula:C19H20N4O2Pureza:98%Forma y color:SolidPeso molecular:336.39DA 4626
CAS:<p>DA 4626 is an H2-receptor antagonist with KB values akin to those in standard assays.</p>Fórmula:C14H18N4Pureza:98%Forma y color:SolidPeso molecular:242.32SIB-1553A hydrochloride
CAS:<p>SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand</p>Fórmula:C13H20ClNOSPureza:99.56% - 99.73%Forma y color:SolidPeso molecular:273.82Telenzepine
CAS:<p>Telenzepine is a potent and selective M1 antimuscarinic.</p>Fórmula:C19H22N4O2SPureza:98%Forma y color:SolidPeso molecular:370.47AC260584
CAS:AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).Fórmula:C20H29FN2O2Forma y color:SolidPeso molecular:348.45Neramexane Mesylate
CAS:<p>Neramexane: NMDA & nicotinic receptor blocker with neuroprotective, antidepressant, and cognitive-enhancing effects.</p>Fórmula:C12H27NO3SPureza:98%Forma y color:SolidPeso molecular:265.41ML381
CAS:<p>ML381 is a M5-orthosteric antagonist with a high selectivity of muscarinic subtype.</p>Fórmula:C21H21N3O4Forma y color:SolidPeso molecular:379.41ML169
CAS:<p>ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM).</p>Fórmula:C21H17BrFN3O4SPureza:98%Forma y color:SolidPeso molecular:506.34Zamifenacin
CAS:Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.Fórmula:C27H29NO3Pureza:98%Forma y color:SolidPeso molecular:415.52BNC375
CAS:BNC375 is a α7 nAChRs type I positive allosteric modulator (EC50: 1.9 μM).Fórmula:C19H23ClN2O3SPureza:98%Forma y color:SolidPeso molecular:394.92(R,R)-Reboxetine mesylate
CAS:<p>(R,R)-Reboxetine mesylate: Antidepressant, high bioavailability, (R,R) enantiomer, selective for noradrenaline, low toxicity.</p>Fórmula:C20H27NO6SForma y color:SolidPeso molecular:409.5GAT107
CAS:<p>GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.</p>Fórmula:C18H17BrN2O2SPureza:99.33%Forma y color:SolidPeso molecular:405.31M1 ligand 1
CAS:<p>Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.</p>Fórmula:C20H21NO2Forma y color:SolidPeso molecular:307.39Benzatropine
CAS:Benzatropine: Central muscarinic blocker, inhibits dopamine uptake, treats Parkinson's symptoms.Fórmula:C21H25NOPureza:98%Forma y color:SolidPeso molecular:307.43Muscarine iodide
CAS:<p>Muscarinic acetylcholine receptor agonist</p>Fórmula:C9H20INO2Pureza:98%Forma y color:SolidPeso molecular:301.17Tridihexethyl chloride
CAS:<p>Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease.</p>Fórmula:C21H36ClNOForma y color:SolidPeso molecular:353.97TC 2559 difumarate
CAS:partial agonist of α4β2 nicotinic acetylcholine receptorFórmula:C12H18N2OC4H404Pureza:98%Forma y color:SolidPeso molecular:380.39TC299423
CAS:<p>TC299423 is a novel agonist for nicotinic acetylcholine receptors (nAChRs). TC299423 modestly selectively targets α6β2 subtype.</p>Fórmula:C11H15N3Forma y color:SolidPeso molecular:189.26SM-21 maleate
CAS:<p>Increases release of acetylcholine,σ2 antagonist</p>Fórmula:C22H28ClNO7Pureza:98%Forma y color:SolidPeso molecular:453.91TC 1698 dihydrochloride
CAS:<p>nicotinic α7 receptor agonist</p>Fórmula:C13H18N2Pureza:98%Forma y color:SolidPeso molecular:202.3Beperidium iodide
CAS:<p>Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93).</p>Fórmula:C23H34IN3O3Forma y color:SolidPeso molecular:527.44WIN 62,577
CAS:<p>WIN 62,577 is a allosteric antagonist of mAChR.</p>Fórmula:C29H31N3OPureza:98%Forma y color:SolidPeso molecular:437.58Benzamide Derivative 1
CAS:Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.Fórmula:C22H34ClN3O3Pureza:>99.99%Forma y color:SolidPeso molecular:423.98Muscarine chloride
CAS:<p>Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>Fórmula:C9H20ClNO2Forma y color:SolidPeso molecular:209.71PHA 543613
CAS:<p>PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.</p>Fórmula:C15H17N3O2Pureza:99.43% - 99.96%Forma y color:SolidPeso molecular:271.31rel-(1R,2R)-Vesamicol Hydrochloride
CAS:<p>Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.</p>Fórmula:C17H26ClNOPureza:99.88%Forma y color:SolidPeso molecular:295.85Temiverine hydrochloride
CAS:Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.Fórmula:C24H36ClNO3Pureza:99.26% - 99.43%Forma y color:SolidPeso molecular:422NB001
CAS:<p>NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.</p>Fórmula:C12H20N6OPureza:99.69%Forma y color:Off-White To Pale Pink SolidPeso molecular:264.33JNJ-39393406
CAS:<p>JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.</p>Fórmula:C19H18F2N6O3Pureza:98.5%Forma y color:SolidPeso molecular:416.38Desformylflustrabromine hydrochloride
CAS:<p>Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.</p>Fórmula:C17H12INO5Pureza:98.12%Forma y color:SolidPeso molecular:437.19Aceclidine
CAS:<p>Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular</p>Fórmula:C9H15NO2Pureza:>99.99%Forma y color:SolidPeso molecular:169.22Dimethindene
CAS:<p>Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.</p>Fórmula:C20H24N2Pureza:98.3% - 98.99%Forma y color:SolidPeso molecular:292.42Posatirelin
CAS:<p>Posatirelin, a synthetic peptide, modulates and nourishes brain systems, aiding in vascular dementia research.</p>Fórmula:C17H28N4O4Pureza:98.08% - 98.87%Forma y color:SolidPeso molecular:352.43ASM-024
CAS:<p>ASM-024, a synthetic piperazine, activates nicotinic and β2-adrenergic receptors for potential asthma and bronchitis treatment with anti-inflammatory effects.</p>Fórmula:C15H25N2Pureza:99.74%Forma y color:SolidPeso molecular:233.37AQW051
CAS:<p>AQW051 (VQW-765) is an oral α7-nAChR activator for cognitive impairments, used in anxiety disorder studies.</p>Fórmula:C19H22N2OPureza:99.94%Forma y color:SolidPeso molecular:294.39Tribendimidine
CAS:<p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>Fórmula:C28H32N6Pureza:≥98%Forma y color:SolidPeso molecular:452.59Oxotremorine M iodide
CAS:<p>Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.</p>Fórmula:C11H19IN2OPureza:99.57%Forma y color:SolidPeso molecular:322.19Iperoxo
CAS:<p>Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.</p>Fórmula:C10H17IN2O2Pureza:99.81%Forma y color:SolidPeso molecular:324.16Xanomeline
CAS:<p>Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.</p>Fórmula:C14H23N3OSPureza:99.61%Forma y color:SolidPeso molecular:281.42NKY80
CAS:<p>NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues.</p>Fórmula:C12H11N3O2Pureza:99.88%Forma y color:SolidPeso molecular:229.23McN-A 343
CAS:<p>McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.</p>Fórmula:C14H18Cl2N2O2Pureza:99.65%Forma y color:SolidPeso molecular:317.21Thonzylamine hydrochloride
CAS:<p>Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.</p>Fórmula:C16H23ClN4OPureza:99.67%Forma y color:White Crystalline PowderPeso molecular:322.83PF-03635659
CAS:<p>PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.</p>Fórmula:C28H32N2O3Pureza:98.39% - 99.83%Forma y color:SolidPeso molecular:444.57CP-810123
CAS:<p>CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.</p>Fórmula:C14H18N4OPureza:98.63% - 99.60%Forma y color:SolidPeso molecular:258.32SCH-900271
CAS:<p>SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.</p>Fórmula:C14H16N2O4Pureza:98.82% - 99.93%Forma y color:SolidPeso molecular:276.29Otenzepad
CAS:Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.Fórmula:C24H31N5O2Pureza:99.79%Forma y color:SolidPeso molecular:421.54GSK233705
CAS:<p>GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.</p>Fórmula:C24H29BrN2Pureza:99.87% - 99.98%Forma y color:SolidPeso molecular:425.4Xanomeline oxalate
CAS:<p>Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.</p>Fórmula:C16H25N3O5SPureza:99.1%Forma y color:SolidPeso molecular:371.45ICL-CCIC-0019
CAS:<p>ICL-CCIC-0019 inhibits ChoKα, causes G1 arrest, ER stress, and cancer cell apoptosis.</p>Fórmula:C26H44Br2N4Pureza:99.54%Forma y color:SolidPeso molecular:572.46APS3
CAS:<p>APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].</p>Fórmula:C18H7Cl2F6N5O5S2Forma y color:SolidPeso molecular:622.31Adenylyl cyclase-IN-1
CAS:<p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>Fórmula:C9H8N2S3Forma y color:SolidPeso molecular:240.37Homatropine hydrochloride
CAS:<p>Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive</p>Fórmula:C16H22ClNO3Forma y color:SolidPeso molecular:311.8Tiotropium Bromide hydrate
CAS:<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Fórmula:C19H24BrNO5S2Pureza:98.44% - 99.41%Forma y color:SolidPeso molecular:490.43PTAC oxalate
CAS:<p>muscarinic receptor ligand</p>Fórmula:C14H21N3O4S2Pureza:98%Forma y color:SolidPeso molecular:359.46mAChR antagonist 1
CAS:<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Fórmula:C19H22N2O2Forma y color:SolidPeso molecular:310.39AR420626
CAS:<p>AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.</p>Fórmula:C21H18Cl2N2O3Pureza:98.62%Forma y color:SolidPeso molecular:417.29Muscarine tosylate
CAS:<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Fórmula:C16H27NO5SForma y color:SolidPeso molecular:345.45Cynandione A
CAS:Cynandione A is an acetophenone derived from Cynanchum wilfordii with anti-inflammatory activity.Fórmula:C16H14O6Pureza:99.62%Forma y color:SolidPeso molecular:302.28UFP-512
CAS:<p>UFP-512 is a selective delta-opioid (DOP) receptor agonist.</p>Fórmula:C31H33N5O5Pureza:98%Forma y color:SolidPeso molecular:555.62A-424274
CAS:<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Fórmula:C14H15N3Pureza:98%Forma y color:SolidPeso molecular:225.29L 687306
CAS:<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Fórmula:C11H15N3OForma y color:SolidPeso molecular:205.26BMS-933043
CAS:<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Fórmula:C16H19N7OPureza:98%Forma y color:SolidPeso molecular:325.37VU0453595
CAS:<p>VU0453595 is a M1 positive allosteric modulator (PAM).</p>Fórmula:C18H15FN4OPureza:99.91%Forma y color:SolidPeso molecular:322.343-Bromocytisine
CAS:<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Fórmula:C11H13BrN2OPureza:99.974%Forma y color:SolidPeso molecular:269.14LG 50643
CAS:<p>LG 50643 is a muscarinic antagonist.</p>Fórmula:C24H34INO2Pureza:98%Forma y color:SolidPeso molecular:495.44VU 0255035
CAS:<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Forma y color:SolidPeso molecular:432.52ABT-418 hydrochloride
CAS:<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Fórmula:C9H15ClN2OForma y color:SolidPeso molecular:202.68Zamifenacin fumarate
CAS:<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Fórmula:C31H33NO7Pureza:99.88%Forma y color:SolidPeso molecular:531.6LY2033298
CAS:<p>LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.</p>Fórmula:C13H14ClN3O2SPureza:99.06%Forma y color:SolidPeso molecular:311.79Timepidium bromide
CAS:<p>Timepidium bromide is an agent of anticholinergic.</p>Fórmula:C17H22BrNOS2Pureza:98%Forma y color:SolidPeso molecular:400.4N-Demethyl MK-6884
CAS:<p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>Fórmula:C24H23N5OForma y color:SolidPeso molecular:397.47Tematropium
CAS:Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.Fórmula:C21H31NO8SPureza:99.89%Forma y color:SolidPeso molecular:457.54Metoquizine
CAS:<p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>Fórmula:C22H27N5OPureza:98%Forma y color:SolidPeso molecular:377.48LY593093
CAS:<p>LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.</p>Fórmula:C32H30FN3O2Pureza:98%Forma y color:SolidPeso molecular:507.6TAAR1 agonist 2
CAS:<p>TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.</p>Fórmula:C9H11NOForma y color:SolidPeso molecular:149.19VU6005806
CAS:<p>VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.</p>Fórmula:C17H16F3N7O2SPureza:98%Forma y color:SolidPeso molecular:439.41VU6007496
CAS:<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Fórmula:C25H27N5O2Forma y color:SolidPeso molecular:429.51WIN 62577
CAS:<p>WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.</p>Fórmula:C29H31N3OForma y color:SolidPeso molecular:437.5761,9-Dideoxyforskolin
CAS:<p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>Fórmula:C22H34O5Pureza:98%Forma y color:SolidPeso molecular:378.5Dihydro-β-erythroidine hydrobromide
CAS:<p>Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).</p>Fórmula:C16H22BrNO3Pureza:98%Forma y color:White SolidPeso molecular:356.26(-)-Cevimeline hydrochloride hemihydrate
<p>(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.</p>Fórmula:C10H19ClNO1·5SPureza:98%Forma y color:SolidPeso molecular:244.78(+)-Sparteine sulfate pentahydrate
<p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>Fórmula:C15H38N2O9SForma y color:SolidPeso molecular:422.54nAChR antagonist 1
CAS:<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Fórmula:C19H22N4O2Forma y color:SolidPeso molecular:338.4(S)-Albuterol
CAS:<p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>Fórmula:C13H21NO3Forma y color:SolidPeso molecular:239.311Dihydro-β-erythroidine
CAS:<p>Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolytic</p>Fórmula:C16H21NO3Forma y color:SolidPeso molecular:275.34Lu 26-046
CAS:<p>Lu 26-046 is a muscarinic receptor agonist.</p>Fórmula:C10H12N2OSForma y color:SolidPeso molecular:208.28(+)-Cevimeline hydrochloride hemihydrate
<p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>Fórmula:C10H19ClNO1·5SPureza:98%Forma y color:SolidPeso molecular:244.78CHF-6366
CAS:<p>CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>Fórmula:C42H48N6O8Forma y color:SolidPeso molecular:764.87UB 165
CAS:<p>Subtype-selective nicotinic agonist</p>Fórmula:C13H15ClN2Pureza:98%Forma y color:SolidPeso molecular:234.72TDI-11861
CAS:<p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>Fórmula:C22H25ClF2N6O3Forma y color:SolidPeso molecular:494.92VU6016235
CAS:VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.Fórmula:C21H22N4OSForma y color:SolidPeso molecular:378.49AChE/BChE-IN-10
CAS:<p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>Fórmula:C26H30N2O2Pureza:99.55% - 99.88%Forma y color:SoildPeso molecular:402.53VU6000918
CAS:<p>VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.</p>Fórmula:C18H17F2N5OSForma y color:SolidPeso molecular:389.42Lupinine
CAS:<p>Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.</p>Fórmula:C10H19NOPureza:99.95%Forma y color:SolidPeso molecular:169.26Oxitropium Bromide
CAS:<p>Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.</p>Fórmula:C19H26BrNO4Pureza:98%Forma y color:SolidPeso molecular:412.32
