AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 575 productos de "AChR"
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Flupyrimin
CAS:<p>Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].</p>Fórmula:C13H9ClF3N3OForma y color:SolidPeso molecular:315.68Adenylyl cyclase type 2 agonist-1
CAS:<p>Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.</p>Fórmula:C27H17BrClNO5Forma y color:SolidPeso molecular:550.78RJR-2403 oxalate
CAS:<p>RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.</p>Fórmula:C14H18N2O4Pureza:98%Forma y color:SolidPeso molecular:278.308Bibn 140
CAS:<p>Bibn 140 is a highly selective M2 antagonist, it is used to treat Alzheimer's disease and other cognitive disorders.</p>Fórmula:C32H44N4O3Pureza:98%Forma y color:SolidPeso molecular:532.72AZD 0328
CAS:<p>AZD 0328 is a nicotinic receptor agonist for α7 neurons.</p>Fórmula:C13H16N2OForma y color:SolidPeso molecular:216.28Nelonicline citrate
CAS:<p>Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.</p>Fórmula:C23H27N3O8SForma y color:SolidPeso molecular:505.54Bradanicline
CAS:<p>Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.</p>Fórmula:C22H23N3O2Forma y color:SolidPeso molecular:361.44Asoxime dichloride
CAS:<p>Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.</p>Fórmula:C14H16Cl2N4O3Pureza:99.86%Forma y color:SolidPeso molecular:359.21Camylofine
CAS:<p>Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.</p>Fórmula:C19H32N2O2·2HClPureza:98%Forma y color:SolidPeso molecular:393.4(Rac)-VU 6008667
CAS:<p>(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.</p>Fórmula:C24H17ClF2N2O2Pureza:99.82%Forma y color:SolidPeso molecular:438.85Pentolinium Tartrate
CAS:<p>Pentolinium Tartrate (Pendine) is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.</p>Fórmula:C15H32N2·2C4H5O6Pureza:98%Forma y color:SolidPeso molecular:538.6AF-DX 384 free base
CAS:<p>AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.</p>Fórmula:C27H38N6O2Pureza:98%Forma y color:SolidPeso molecular:478.63Pozanicline
CAS:<p>Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.</p>Fórmula:C11H16N2OPureza:98%Forma y color:SolidPeso molecular:192.26CB-6673567
CAS:<p>CB-6673567 is a selective inhibitor of adenylyl cyclase.</p>Fórmula:C19H14N4O3Forma y color:SolidPeso molecular:346.34NGX-267
CAS:<p>NGX-267, a muscarinic M1 agonist, is used potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive.</p>Fórmula:C10H18N2OSForma y color:SolidPeso molecular:214.33Dac 5945
CAS:<p>DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.</p>Fórmula:C19H30ClN3OPureza:98%Forma y color:SolidPeso molecular:351.91Hexocyclium metilsulfate
CAS:<p>Hexocyclium metilsulfate has anti-gastric secretory effects in humans.</p>Fórmula:C21H36N2O5SPureza:98%Forma y color:SolidPeso molecular:428.59GS 283
CAS:<p>GS 283 is a Ca(2+) antagonist. GS 283 is also a weak histamine and muscarinic receptor blocker in rat and guinea pig tracheal smooth muscles.</p>Fórmula:C17H17NO3Forma y color:SolidPeso molecular:283.32(R)-VU 6008667
CAS:<p>(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).</p>Fórmula:C24H17ClF2N2O2Forma y color:SolidPeso molecular:438.85Anisodine hydrobromide
CAS:<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Fórmula:C17H22BrNO5Forma y color:White Crystals Or Crystalline PowderPeso molecular:400.27Btm 1042
CAS:<p>Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.</p>Fórmula:C21H26ClN3OSForma y color:SolidPeso molecular:403.97Hyoscyamine hydrobromide
CAS:<p>Hyoscyamine hydrobromide is an agent of anticholinergic.</p>Fórmula:C17H24BrNO3Pureza:98%Forma y color:SolidPeso molecular:370.28Sazetidine A dihydrochloride
CAS:<p>α4β2 nicotinic acetylcholine receptor ligand</p>Fórmula:C15H21ClN2O2Pureza:98%Forma y color:SolidPeso molecular:296.79FR 121196
CAS:<p>FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.</p>Fórmula:C12H16FN3O3SForma y color:SolidPeso molecular:301.34Prifuroline
CAS:<p>Prifuroline is an agent of antiarrhythmic.</p>Fórmula:C14H16N2OPureza:98%Forma y color:SolidPeso molecular:228.29Epibatidine 2HCl
CAS:<p>Epibatidine 2HCl is a potent nicotinic agonist.</p>Fórmula:C11H15Cl3N2Pureza:98%Forma y color:SolidPeso molecular:281.61Flutropium Bromide
CAS:<p>Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.</p>Fórmula:C24H29BrFNO3Pureza:98%Forma y color:SolidPeso molecular:478.39Vesamicol
CAS:Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.Fórmula:C17H25NOPureza:98%Forma y color:SolidPeso molecular:259.39Siltenzepine
CAS:<p>Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.</p>Fórmula:C19H20ClN3O4Pureza:98%Forma y color:SolidPeso molecular:389.83L 858051
CAS:<p>L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.</p>Fórmula:C29H48N2O7Forma y color:SolidPeso molecular:536.7DBO-83
CAS:<p>DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.</p>Fórmula:C10H15Cl3N4Pureza:98%Forma y color:SolidPeso molecular:297.61ADX-10061
CAS:<p>ADX-10061 is a dopamine D1 receptor antagonist.</p>Fórmula:C19H20N2O4Forma y color:SolidPeso molecular:340.37JN403
CAS:<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Fórmula:C16H21FN2O2Forma y color:SolidPeso molecular:292.35Tebanicline tosylate
CAS:<p>Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.</p>Fórmula:C16H19ClN2O4SPureza:98%Forma y color:SolidPeso molecular:370.85Terodiline hydrochloride
CAS:<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Fórmula:C20H28ClNPureza:98%Forma y color:SolidPeso molecular:317.9YM-46303
CAS:<p>YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in</p>Fórmula:C20H23ClN2O2Pureza:>99.99%Forma y color:SolidPeso molecular:358.86CHF5407
CAS:<p>CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on</p>Fórmula:C27H25BrF4N2O3SPureza:>99.99%Forma y color:SolidPeso molecular:613.46YM-58790
CAS:<p>YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.</p>Fórmula:C27H31N3O2Pureza:98.59%Forma y color:SoildPeso molecular:429.55Metixene hydrochloride
CAS:<p>Metixene hydrochloride is an anticholinergic antiparkinsonian agent.</p>Fórmula:C20H24ClNSPureza:98%Forma y color:SolidPeso molecular:345.93PQCA
CAS:<p>PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.</p>Fórmula:C22H20N4O3Pureza:99.88%Forma y color:SolidPeso molecular:388.42Penehyclidine hydrochloride
CAS:<p>Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.</p>Fórmula:C20H30ClNO2Pureza:99.79%Forma y color:SolidPeso molecular:351.91PD-102807
CAS:<p>PD-102807 is a selective and competitive M4 muscarinic receptor antagonist for Parkinson's disease research, inhibit airway smooth muscle (ASM) contraction.</p>Fórmula:C23H24N2O4Pureza:98.90%Forma y color:SolidPeso molecular:392.45S 24795
CAS:<p>S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist.</p>Fórmula:C14H13BrINOPureza:99.934%Forma y color:SolidPeso molecular:418.07S16961
CAS:<p>S16961 (S169611) is an agonist of nicotinic receptor.</p>Fórmula:C41H71NO6Pureza:99.69%Forma y color:SolidPeso molecular:674.01Afacifenacin
CAS:<p>Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.</p>Fórmula:C27H26F3N3O2Pureza:99.83%Forma y color:SolidPeso molecular:481.51UP202-56
CAS:<p>UP202-56 is an adenosinergic agonist and is an adenosine analog.</p>Fórmula:C33H37N7O4Pureza:98%Forma y color:SolidPeso molecular:595.69CB-7921220
CAS:<p>CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.</p>Fórmula:C14H12N2O2Pureza:99.59%Forma y color:SolidPeso molecular:240.26Cimetropium Bromide
CAS:<p>Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.</p>Fórmula:C21H28BrNO4Forma y color:SolidPeso molecular:438.36GP531
CAS:<p>GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.</p>Fórmula:C16H21N5O4Forma y color:SolidPeso molecular:347.37GAT107
CAS:<p>GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.</p>Fórmula:C18H17BrN2O2SPureza:99.33%Forma y color:SolidPeso molecular:405.31
