AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 575 productos de "AChR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
mAChr-in-1
CAS:<p>mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).</p>Fórmula:C23H25IN2O2Pureza:98%Forma y color:SolidPeso molecular:488.36Darenzepine
CAS:<p>Darenzepine is a muscarinic receptor inhibitor.</p>Fórmula:C21H21N3O2Pureza:99.87%Forma y color:SolidPeso molecular:347.41UB 165 fumarate
CAS:<p>UB 165 fumarate is a nAChR agonist, α4β2 partial, α3β2 full, with a 0.27 nM Ki for [3H]-nicotine in rat brain.</p>Fórmula:C17H19ClN2O4Pureza:99.72%Forma y color:SolidPeso molecular:350.8CDD0102
CAS:<p>CDD0102 is a potent agonist of M1 Muscarinic receptor.</p>Fórmula:C8H12N4OPureza:98%Forma y color:SolidPeso molecular:180.215-Iodo-A-85380 dihydrochloride
CAS:<p>α4β2 and α6β2 nicotinic acetylcholine receptors agonist</p>Fórmula:C9H13Cl2IN2OPureza:98%Forma y color:SolidPeso molecular:363.02Dimethyl-W84 (dibromide)
CAS:<p>Dimethyl-W84, selective M2 muscarinic receptor modulator; slows N-methylscopolamine release, EC50=3 nM.</p>Fórmula:C34H48Br2N4O4Forma y color:SolidPeso molecular:736.59LY 2087101
CAS:<p>Allosteric potentiator of α7, α4β2 and α4β4 nAChRs</p>Fórmula:C15H11FN2OS2Pureza:98%Forma y color:SolidPeso molecular:318.39AR-R 17779 hydrochloride
CAS:<p>AR-R17779 hydrochloride: potent α7 nAChR agonist; K i : 92 nM (α7), 16,000 nM (α4β2); enhances rat cognition; anxiolytic; anti-inflammatory.</p>Fórmula:C9H15ClN2O2Forma y color:SolidPeso molecular:218.68Elucaine
CAS:<p>Elucaine is an antagonist of the muscarinic acetylcholine receptor. It has anti-ulcerative activity.</p>Fórmula:C19H23NO2Pureza:98%Forma y color:SolidPeso molecular:297.39(R,R)-Glycopyrrolate
CAS:<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>Fórmula:C19H28BrNO3Pureza:98%Forma y color:SolidPeso molecular:398.34SIB 1508Y maleate
CAS:<p>neuronal nicotinic ACh receptor agonist</p>Fórmula:C16H18N2O4Pureza:98%Forma y color:SolidPeso molecular:302.33LRE1
CAS:<p>LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor.</p>Fórmula:C12H13ClN4SPureza:>99.99%Forma y color:SolidPeso molecular:280.78Terodiline
CAS:<p>Terodiline is an orally available selective muscarinic M1 receptor and calcium channel antagonist for the study of diseases caused by abnormal bladder function.</p>Fórmula:C20H27NPureza:98.20% - 99.59%Forma y color:SolidPeso molecular:281.44Methacholine bromide
CAS:<p>Methacholine bromide is a potent M3 agonist for diagnosing asthma by identifying bronchial hyperresponsiveness.</p>Fórmula:C8H18BrNO2Forma y color:SolidPeso molecular:240.141Nuvenzepine
CAS:<p>Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.</p>Fórmula:C19H20N4O2Pureza:98%Forma y color:SolidPeso molecular:336.39DA 4626
CAS:<p>DA 4626 is an H2-receptor antagonist with KB values akin to those in standard assays.</p>Fórmula:C14H18N4Pureza:98%Forma y color:SolidPeso molecular:242.32Telenzepine
CAS:<p>Telenzepine is a potent and selective M1 antimuscarinic.</p>Fórmula:C19H22N4O2SPureza:98%Forma y color:SolidPeso molecular:370.47AC260584
CAS:AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).Fórmula:C20H29FN2O2Forma y color:SolidPeso molecular:348.45Neramexane Mesylate
CAS:<p>Neramexane: NMDA & nicotinic receptor blocker with neuroprotective, antidepressant, and cognitive-enhancing effects.</p>Fórmula:C12H27NO3SPureza:98%Forma y color:SolidPeso molecular:265.41Chlorisondamine diiodide
CAS:<p>long lasting nicotinic antagonist</p>Fórmula:C14H20Cl4I2N2Forma y color:SolidPeso molecular:611.94ML381
CAS:<p>ML381 is a M5-orthosteric antagonist with a high selectivity of muscarinic subtype.</p>Fórmula:C21H21N3O4Forma y color:SolidPeso molecular:379.41ML169
CAS:<p>ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM).</p>Fórmula:C21H17BrFN3O4SPureza:98%Forma y color:SolidPeso molecular:506.34Zamifenacin
CAS:<p>Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.</p>Fórmula:C27H29NO3Pureza:98%Forma y color:SolidPeso molecular:415.52BNC375
CAS:<p>BNC375 is a α7 nAChRs type I positive allosteric modulator (EC50: 1.9 μM).</p>Fórmula:C19H23ClN2O3SPureza:98%Forma y color:SolidPeso molecular:394.92(R,R)-Reboxetine mesylate
CAS:<p>(R,R)-Reboxetine mesylate: Antidepressant, high bioavailability, (R,R) enantiomer, selective for noradrenaline, low toxicity.</p>Fórmula:C20H27NO6SForma y color:SolidPeso molecular:409.5M1 ligand 1
CAS:<p>Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.</p>Fórmula:C20H21NO2Forma y color:SolidPeso molecular:307.39Benzatropine
CAS:<p>Benzatropine: Central muscarinic blocker, inhibits dopamine uptake, treats Parkinson's symptoms.</p>Fórmula:C21H25NOPureza:98%Forma y color:SolidPeso molecular:307.43Muscarine iodide
CAS:<p>Muscarinic acetylcholine receptor agonist</p>Fórmula:C9H20INO2Pureza:98%Forma y color:SolidPeso molecular:301.17Tridihexethyl chloride
CAS:<p>Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease.</p>Fórmula:C21H36ClNOForma y color:SolidPeso molecular:353.97TC 2559 difumarate
CAS:<p>partial agonist of α4β2 nicotinic acetylcholine receptor</p>Fórmula:C12H18N2OC4H404Pureza:98%Forma y color:SolidPeso molecular:380.39TC299423
CAS:<p>TC299423 is a novel agonist for nicotinic acetylcholine receptors (nAChRs). TC299423 modestly selectively targets α6β2 subtype.</p>Fórmula:C11H15N3Forma y color:SolidPeso molecular:189.26SM-21 maleate
CAS:<p>Increases release of acetylcholine,σ2 antagonist</p>Fórmula:C22H28ClNO7Pureza:98%Forma y color:SolidPeso molecular:453.91TC 1698 dihydrochloride
CAS:<p>nicotinic α7 receptor agonist</p>Fórmula:C13H18N2Pureza:98%Forma y color:SolidPeso molecular:202.3Beperidium iodide
CAS:<p>Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93).</p>Fórmula:C23H34IN3O3Forma y color:SolidPeso molecular:527.44WIN 62,577
CAS:<p>WIN 62,577 is a allosteric antagonist of mAChR.</p>Fórmula:C29H31N3OPureza:98%Forma y color:SolidPeso molecular:437.58Benzamide Derivative 1
CAS:<p>Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.</p>Fórmula:C22H34ClN3O3Pureza:>99.99%Forma y color:SolidPeso molecular:423.98Alvameline
CAS:<p>Alvameline (Lu25-109) is a partial M1 agonist. Alvameline (Lu25-109) also is a M2/M3 antagonist.</p>Fórmula:C9H15N5Pureza:98%Forma y color:SolidPeso molecular:193.25Muscarine chloride
CAS:<p>Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>Fórmula:C9H20ClNO2Forma y color:SolidPeso molecular:209.71Quifenadine
CAS:<p>Quifenadine, an H1-histamine receptor blocker, has antiarrhythmic properties.</p>Fórmula:C20H23NOPureza:98%Forma y color:SolidPeso molecular:293.4DAU 5884 hydrochloride
CAS:<p>muscarinic M3 receptor antagonist</p>Fórmula:C17H22ClN3O3Pureza:98%Forma y color:SolidPeso molecular:351.83Nelonicline
CAS:<p>Nelonicline is a selective agonist of neuronal nicotinic receptors.</p>Fórmula:C17H19N3OSPureza:98%Forma y color:SolidPeso molecular:313.42BTM-1086
CAS:<p>BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.</p>Fórmula:C21H25N3OSPureza:98%Forma y color:SolidPeso molecular:367.51CP-601932
CAS:<p>CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.</p>Fórmula:C12H12F3NForma y color:SolidPeso molecular:227.23Eucatropine
CAS:<p>Eucatropine, an anticholinergic agent, acts as a potent inhibitor of the muscarinic acetylcholine receptor (mAChR) with an IC 50 value of 0.583 μM.</p>Fórmula:C17H25NO3Forma y color:SolidPeso molecular:291.39Thiochrome
CAS:<p>Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.</p>Fórmula:C12H14N4OSPureza:98%Forma y color:SolidPeso molecular:262.33VU0090157
CAS:<p>VU0090157, a novel allosteric potentiators of M1 muscarinic receptor, may provide novel treatments for schizophrenia and Alzheimer's disease.</p>Fórmula:C19H21N3O7Pureza:98%Forma y color:SolidPeso molecular:403.39S-(+)-Mecamylamine hydrochloride
CAS:<p>Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity.</p>Fórmula:C11H22ClNForma y color:SolidPeso molecular:203.75T761-0184
CAS:<p>T761-0184 is a potent antagonist of α7 nicotinic receptor (nAChR) [1].</p>Fórmula:C16H20FN3OForma y color:SolidPeso molecular:289.35Revatropate
CAS:<p>Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.</p>Fórmula:C19H27NO4SForma y color:SolidPeso molecular:365.49Rispenzepine
CAS:<p>Rispenzepine, a novel mAChRs M1/M3 antagonist, treats immune, infections, and respiratory issues.</p>Fórmula:C19H20N4O2Pureza:98%Forma y color:SolidPeso molecular:336.39
