NMDAR
Los inhibidores del receptor de N-Metil-D-Aspartato (NMDAR) son compuestos que bloquean la actividad de los NMDARs, un subtipo de receptores de glutamato que desempeñan un papel crítico en la plasticidad sináptica, el aprendizaje y la memoria. La sobreactivación de los NMDARs está implicada en la excitotoxicidad, que puede llevar a daño neuronal y está asociada con condiciones como el accidente cerebrovascular, el trauma craneoencefálico y enfermedades neurodegenerativas. Los inhibidores de NMDAR son herramientas esenciales para estudiar la excitotoxicidad y para desarrollar terapias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de NMDAR para apoyar su investigación en función sináptica, neuroprotección y trastornos cognitivos.
Se han encontrado 28 productos de "NMDAR"
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Mephenesin
CAS:<p>Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.</p>Fórmula:C10H14O3Pureza:99.49%Forma y color:SolidPeso molecular:182.22SDZ 220-040 ammonium
<p>SDZ 220-040 ammonium is a competitive glutamate ionotropic receptor NMDA antagonist used in the study of neurological disorders.</p>Fórmula:C16H19Cl2N2O6PPureza:98.47%Forma y color:SolidPeso molecular:437.21L-689560
CAS:<p>L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.</p>Fórmula:C17H15Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:380.23S1R agonist 2
CAS:<p>S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.</p>Fórmula:C21H27NOPureza:98.85%Forma y color:SolidPeso molecular:309.45GluN2B receptor modulator-1
CAS:<p>GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.</p>Fórmula:C17H15F3N4O2SPureza:99.56%Forma y color:SolidPeso molecular:396.39QNZ46
CAS:<p>QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist.</p>Fórmula:C24H17N3O6Pureza:99.65%Forma y color:SolidPeso molecular:443.41Flutriafol
CAS:<p>Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist</p>Fórmula:C16H13F2N3OPureza:98.75%Forma y color:SolidPeso molecular:301.29DNQX disodium salt
CAS:<p>DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptor</p>Fórmula:C8H2N4Na2O6Pureza:98.93%Forma y color:SolidPeso molecular:296.1Dizocilpine Maleate
CAS:<p>Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor with Kd of 37.2 nM in rat brain membranes.</p>Fórmula:C20H19NO4Pureza:99% - 99.96%Forma y color:White SolidPeso molecular:337.38Rapastinel Trifluoroacetate
CAS:<p>Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties.</p>Fórmula:C20H32F3N5O8Pureza:99.01% - 99.77%Forma y color:SolidPeso molecular:527.49ZL006
CAS:<p>ZL006 is an effective inhibitor of nNOS/PSD-95 interaction. ZL006 also inhibits NMDA receptor-mediated NO synthesis.</p>Fórmula:C14H11Cl2NO4Pureza:98.29%Forma y color:SolidPeso molecular:328.15Traxoprodil
CAS:<p>Traxoprodil (CP101606) is a selective NMDA antagonist and protects hippocampal neurons (IC50: 10 nM).</p>Fórmula:C20H25NO3Pureza:99.89%Forma y color:SolidPeso molecular:327.42(-)-Dizocilpine maleate
CAS:<p>(-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.</p>Fórmula:C20H19NO4Pureza:>99.99%Forma y color:White SolidPeso molecular:337.37Acamprosate
CAS:<p>Acamprosate, alcohol dependence treatment. Affordable Excellence: Reliable Quality You Can Trust</p>Fórmula:C5H11NO4SPureza:98.30%Forma y color:SolidPeso molecular:181.21Glypromate acetate(32302-76-4 free base)
<p>Glypromate acetate is a neuroprotective agent, is a weak NMDA receptor agonist.</p>Fórmula:C14H23N3O8Pureza:99.94%Forma y color:SolidPeso molecular:361.35Flupirtine maleate
CAS:<p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>Fórmula:C15H17FN4O2·C4H4O4Pureza:99.5% - 99.9%Forma y color:Off-White Crystalline PowderPeso molecular:420.39L-701324
CAS:<p>L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.</p>Fórmula:C21H14ClNO3Pureza:98.63% - >99.99%Forma y color:SolidPeso molecular:363.79TCN 201
CAS:<p>TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.</p>Fórmula:C21H17ClFN3O4SPureza:98.5%Forma y color:SolidPeso molecular:461.89Eliprodil
CAS:<p>Eliprodil (SL-820715), NR2B-NMDA receptor blocker (IC50: 1 uM), less potent on NR2A/NR2C (IC50>100 uM), explored for Parkinson's and movement issues.</p>Fórmula:C20H23ClFNOPureza:99.53% - 99.77%Forma y color:SolidPeso molecular:347.85Radiprodil
CAS:<p>Radiprodil (RGH-896) is an oral NMDA NR2B antagonist for potential DPNP neuropathic pain treatment.</p>Fórmula:C21H20FN3O4Pureza:99.74%Forma y color:SolidPeso molecular:397.4MDL-29951
CAS:<p>MDL-29951 is a novel glycine antagonist of NMDA receptor activation.</p>Fórmula:C12H9Cl2NO4Pureza:98.79% - 99.49%Forma y color:SolidPeso molecular:302.11Dizocilpine
CAS:<p>MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.</p>Fórmula:C16H15NPureza:99.85% - 99.97%Forma y color:SolidPeso molecular:221.3Gavestinel sodium
CAS:<p>Gavestinel (GV 150526): potent, selective oral NMDA antagonist; binds glycine site, pKi 8.5; studied for acute ischemic stroke.</p>Fórmula:C18H11Cl2N2NaO3Pureza:99.04%Forma y color:SolidPeso molecular:397.19UK-240455
CAS:<p>UK-240455: Potent NMDA glycine antagonist with neuroprotection and motor function benefits in Parkinson's.</p>Fórmula:C11H11Cl2N3O5SPureza:98.34% - 99.84%Forma y color:SolidPeso molecular:368.19CGP 37849
CAS:<p>CGP 37849: oral NMDA antagonist (Ki=35 nM), anticonvulsant, with antidepressant/anxiolytic effects.</p>Fórmula:C6H12NO5PPureza:99.87%Forma y color:White SolidPeso molecular:209.14Dalzanemdor
CAS:<p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>Fórmula:C27H43F3O2Pureza:98.2% - >99.99%Forma y color:SolidPeso molecular:456.62CGP 78608 hydrochloride
CAS:<p>CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).</p>Fórmula:C11H14BrClN3O5PPureza:99.85%Forma y color:SolidPeso molecular:414.58R-(+)-EU-1180-453
CAS:<p>R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.</p>Fórmula:C22H21FN2O3Pureza:99.63%Forma y color:SolidPeso molecular:380.41
