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Acetil-CoA Carboxilasa

Acetil-CoA Carboxilasa

Los inhibidores de Acetil-CoA Carboxilasa (ACC) son compuestos que inhiben la actividad de ACC, una enzima clave en la biosíntesis de ácidos grasos al convertir acetil-CoA en malonil-CoA. Inhibir ACC puede reducir la síntesis de lípidos, lo que hace que estos inhibidores sean valiosos en la investigación relacionada con trastornos metabólicos, obesidad y cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de ACC para apoyar su investigación en vías metabólicas, metabolismo de lípidos y desarrollo terapéutico.

Se han encontrado 35 productos de "Acetil-CoA Carboxilasa"

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  • CMS-121

    CAS:
    CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor.
    Fórmula:C20H19NO3
    Pureza:98.71%
    Forma y color:Solid
    Peso molecular:321.37
  • CP-610431

    CAS:
    CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.
    Fórmula:C30H37N3O2
    Forma y color:Solid
    Peso molecular:471.645
  • Lipid Metabolism Compound Library


    <p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>
    Forma y color:Odour Solid
  • Fluazifop-P-butyl

    CAS:
    Fluazifop-P-butyl is an arylophenoxypropionate group graminicide that functions as an inhibitor of acetyl-CoA carboxylase (ACCase)[1].
    Fórmula:C19H20F3NO4
    Forma y color:Light Yellow Liquid
    Peso molecular:383.36
  • Spiromesifen

    CAS:
    Spiromesifen is a useful miticide and insecticide in plant breeding. It is particuarly useful against spider mites and whiteflies in vitro.
    Fórmula:C23H30O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:370.48
  • MK-4074

    CAS:
    MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).
    Fórmula:C33H31N3O6
    Forma y color:Solid
    Peso molecular:565.62
  • Sethoxydim

    CAS:
    <p>Sethoxydim is an effective herbicide.</p>
    Fórmula:C17H29NO3S
    Forma y color:Oily Liquid Sethoxydim Is An Oily Odorless Liquid Non Corrosive Used As An Herbicide
    Peso molecular:327.48
  • Clodinafop-propargyl

    CAS:
    Clodinafop-propargyl is used to control grass weeds in cereals postemergence, targeting species like Avena and Lolium.
    Fórmula:C17H13ClFNO4
    Pureza:98.85%
    Forma y color:White Crystal Powder
    Peso molecular:349.74
  • Quizalofop-p-ethyl

    CAS:
    <p>Quizalofop-p-ethyl ((R)-Quizalofop ethyl) is a selective post-emergent herbicide for annual and perennial weeds, acetyl-CoA carboxylase (ACCase) inhibitor.</p>
    Fórmula:C19H17ClN2O4
    Pureza:97.87%
    Forma y color:White Powder Crystal
    Peso molecular:372.80
  • Cyhalofop-butyl

    CAS:
    Cyhalofop-butyl is an ACCase (acetyl-coenzyme A carboxylase) inhibitor and herbicide that suppresses plant lipid synthesis at the meristematic level.
    Fórmula:C20H20FNO4
    Pureza:99.83%
    Forma y color:Solid
    Peso molecular:357.38
  • CP-640186

    CAS:
    CP-640186 is an isozyme-nonselective ACCase inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.
    Fórmula:C30H35N3O3
    Pureza:99.87%
    Forma y color:Solid
    Peso molecular:485.62
  • ND-646

    CAS:
    ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2,
    Fórmula:C28H32N4O7S
    Pureza:98.64%
    Forma y color:Solid
    Peso molecular:568.64
  • Firsocostat

    CAS:
    <p>Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM).</p>
    Fórmula:C28H31N3O8S
    Pureza:98% - 98.46%
    Forma y color:Solid
    Peso molecular:569.63
  • CP-640186 hydrochloride

    CAS:
    <p>CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat</p>
    Fórmula:C30H36ClN3O3
    Pureza:98.86%
    Forma y color:Solid
    Peso molecular:522.08
  • Olumacostat Glasaretil

    CAS:
    Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
    Fórmula:C26H43NO7
    Pureza:97.79% - 99.34%
    Forma y color:Solid
    Peso molecular:481.62
  • PF-05221304

    CAS:
    PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
    Fórmula:C28H30N4O5
    Pureza:98.82% - 99.50%
    Forma y color:Solid
    Peso molecular:502.56
  • Haloxyfop

    CAS:
    (±)-Haloxyfop (Haloxyfop Acid) is a herbicide.
    Fórmula:C15H11ClF3NO4
    Pureza:99.96% - >99.99%
    Forma y color:Solid
    Peso molecular:361.7
  • TOFA

    CAS:
    TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).
    Fórmula:C19H32O4
    Pureza:97.52% - 98.98%
    Forma y color:Solid
    Peso molecular:324.45
  • ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)


    Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
    Forma y color:Lyophilized Powder
    Peso molecular:67.6 kDa (predicted)
  • ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)


    Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
    Forma y color:Lyophilized Powder
    Peso molecular:69.9 kDa (predicted)