DPP-4
Los inhibidores de DPP-4 son compuestos que inhiben la Dipeptidil Peptidasa-4, una enzima implicada en la inactivación de las hormonas incretinas, que regulan el metabolismo de la glucosa. Al inhibir DPP-4, estos compuestos ayudan a prolongar la acción de las hormonas incretinas, mejorando la secreción de insulina y reduciendo los niveles de glucosa en sangre. Los inhibidores de DPP-4 se utilizan ampliamente en el tratamiento de la diabetes tipo 2 y en investigaciones centradas en trastornos metabólicos. En CymitQuimica, ofrecemos inhibidores de DPP-4 para apoyar su investigación en endocrinología, manejo de la diabetes y enfermedades metabólicas.
Se han encontrado 91 productos para "DPP-4".
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DPP-4/GPR119 modulator 1
CAS:Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.Fórmula:C30H39ClN10O3Forma y color:SolidPeso molecular:623.15MPO-IN-6
MPO-IN-6 (compound ADC) is an electrophilic agent with excellent antioxidant and anti-inflammatory properties. It acts as an inhibitor of myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD), with IC50 values of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 may serve as a potential cardiovascular protective agent.Fórmula:C16H12N2O6Forma y color:SolidPeso molecular:328.06954Hypoglycemic agent 4
Hypoglycemic agent 4 (Compound 5b) is an orally active tetrahydroacridine derivative with blood sugar-lowering properties. It demonstrates strong binding affinity to critical diabetes targets: DPP-IV, SGLT1, and GLUT2. Hypoglycemic agent 4 effectively inhibits glucose diffusion and reduces fasting blood glucose levels in Streptozotocin-induced diabetic rats, comparable to Gliclazide. It is applicable in type 2 diabetes research.VAMP
VAMP is a tetrapeptide that acts as a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor, exhibiting an IC50 of 1.00 μM and a Kd of 6.89 μM. It effectively targets the DPP-IV-GLP-1 axis and is utilized in the research of type 2 diabetes.Fórmula:C18H32N4O5SForma y color:SolidPeso molecular:416.535Sitagliptin fenilalanil hydrochloride
CAS:Sitagliptin fenilalanil hydrochloride is an orally active DPP-4 inhibitor. Sitagliptin fenilalanil hydrochloride is used in diabetes research.Fórmula:C25H25ClF6N6O2Pureza:98.32%Forma y color:White SolidPeso molecular:590.95Fotagliptin
CAS:Fotagliptin is a dipeptidyl peptidase IV inhibitor.Fórmula:C17H19FN6OForma y color:SolidPeso molecular:342.37SGLT2-IN-5
SGLT2-IN-5 (Compound 99) is an orally active SGLT2 inhibitor with IC₅₀ values of 0.8 nM for SGLT2, 23 nM for SGLT1, and 58 nM for DPP4. In diabetic rat models, SGLT2-IN-5 effectively regulates blood glucose and increases the levels of active GLP-1. It is suitable for research on type 2 diabetes.Dutogliptin tartrate
CAS:Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Fórmula:C14H26BN3O9Pureza:98%Forma y color:SolidPeso molecular:391.18Linagliptin Methyldimer
CAS:Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.Fórmula:C50H56N16O4Pureza:99.91%Forma y color:SolidPeso molecular:945.08(-)-Sitagliptin Carbamoyl Glucuronide
CAS:Minor phase II metabolite of DPP-4 inhibitor sitagliptin, found in rat and dog plasma.Fórmula:C23H23F6N5O9Forma y color:SolidPeso molecular:627.453Sitagliptin fenilalanil
CAS:Sitagliptin fenilalanil is a DPP-4 (dipeptidyl peptidase-4) inhibitor that inhibits DPP-4 enzyme activity.Fórmula:C25H24F6N6O2Pureza:98.82%Forma y color:SolidPeso molecular:554.49DPP4/CD26 Protein, Mouse, Recombinant (His)
DPP4/CD26 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:85.69 kDa (predicted); 100-120 kDa (due to glycosylation)DPP4/CD26 Protein, Mouse, Recombinant (hFc)
DPP4/CD26 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Pureza:99% - > 95 % as determined by SDS-PAGE.Forma y color:White Lyophilized PowderPeso molecular:112.9 kDa (predicted)Retagliptin
CAS:Retagliptin is a DPP-4 inhibitor potentially used to treat Type 2 diabetes.Fórmula:C19H18F6N4O3Forma y color:SolidPeso molecular:464.36Nateglinide-D5
CAS:Nateglinide D5 is a deuterium labeled Nateglinide.Fórmula:C19H27NO3Pureza:98%Forma y color:SolidPeso molecular:322.45Saxagliptin hydrochloride
CAS:Saxagliptin: oral DPP-4 inhibitor, enhances incretins, manages type 2 diabetes by reducing glucose levels.Fórmula:C18H26ClN3O2Forma y color:SolidPeso molecular:351.87Alogliptin-13CD3
CAS:Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.Fórmula:C18H21N5O2Pureza:98%Forma y color:SolidPeso molecular:343.4Teneligliptin-D8
CAS:Teneligliptin D8 a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting inhibitor of DPP-4.Fórmula:C22H30N6OSPureza:98%Forma y color:SolidPeso molecular:434.63Diprotin A TFA
CAS:Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).Fórmula:C19H32F3N3O6Forma y color:SolidPeso molecular:455.47YS110
CAS:YS110 is a humanized anti-CD26 (DPP4) IgG1 monoclonal antibody. It induces CD26 nuclear translocation via the caveolin pathway and inhibits tumor cell proliferation by delaying the G2/M cell cycle transition. Additionally, YS110 blocks the binding of MERS CoV S1 to CD26, thereby preventing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. This compound is applicable in research on cancer and infections, including malignant mesothelioma and MERS.
