Glutaminasa
Los inhibidores de la glutaminasa son compuestos que inhiben la glutaminasa, una enzima que cataliza la conversión de glutamina en glutamato, un paso crítico en el metabolismo celular, especialmente en las células cancerosas. La glutaminasa desempeña un papel clave en la provisión de energía y precursores biosintéticos para las células en rápida proliferación. Los inhibidores de la glutaminasa son importantes para explorar las dependencias metabólicas en las células cancerosas y desarrollar posibles estrategias terapéuticas. En CymitQuimica, proporcionamos inhibidores de la glutaminasa para apoyar su investigación en metabolismo del cáncer, bioenergética celular y descubrimiento terapéutico.
Se han encontrado 46 productos de "Glutaminasa"
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ZM39923
CAS:ZM39923 is an effective JAK3 inhibitor (IC50=79 nM), simultaneously inhibiting TGM2 and Factor XIIIa (IC50=10/25 nM).Fórmula:C23H25NOPureza:98%Forma y color:SolidPeso molecular:331.45NC9 TG2 inhibitor
CAS:NC9 is an irreversible inhibitor of transglutaminase 2 (TG2) and also inhibits Factor XIIIA (FXIIIA).Fórmula:C35H47N5O8SPureza:98%Forma y color:SolidPeso molecular:697.84AA9 TG2 inhibitor
CAS:AA9 is a novel transglutaminase (TG2) inhibitor.Fórmula:C32H36N4O5Forma y color:SolidPeso molecular:556.65AA10 TG2 inhibitor
CAS:AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).Fórmula:C32H36N4O5Forma y color:SolidPeso molecular:556.65GLS1 Inhibitor-3
CAS:GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.Fórmula:C30H32N10O2SForma y color:SolidPeso molecular:596.71VA4 TG2 inhibitor
CAS:VA4 is a novel irreversible TG2 transamidase site-specific inhibitor.Fórmula:C33H41N5O6SForma y color:SolidPeso molecular:635.77α-Glucosidase-IN-5
CAS:α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM.Fórmula:C15H13NO3Forma y color:SolidPeso molecular:255.27Glutaminase-IN-4
CAS:Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor (IC50: 2.3 μM).Fórmula:C23H22N6O2S2Forma y color:SolidPeso molecular:478.59Duazomycin
CAS:Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.Fórmula:C8H11N3O4Forma y color:SolidPeso molecular:213.19CP4d inhibitor
CAS:CP4d is a novel reversible tg2 transamidase site-specific inhibitorFórmula:C18H13N5O5Forma y color:SolidPeso molecular:379.33THDP-17
CAS:THDP-17 is a inhibitor of glutaminase. THDP-17 shows a partial uncompetitive inhibition in vitro.Fórmula:C12H16N2SPureza:98%Forma y color:SolidPeso molecular:220.33JHU-083
CAS:JHU-083 is a glutaminase antagonist that improves cognition and normalizes aberrant hippocampal glutaminase activity in APOE4 mice.Fórmula:C14H24N4O4Pureza:97.89% - 99.53%Forma y color:SolidPeso molecular:312.37GLS1 Inhibitor
CAS:GLS1 inhibitor blocks glutaminase 1 (IC50=0.021 μM), hinders NCI H1703 NSCLC cell growth in vitro (GI50=0.011 μM), and suppresses tumors in mice.Fórmula:C19H21N7O2SForma y color:SolidPeso molecular:411.48IPN60090
CAS:IPN60090: potent oral GLS1 inhibitor, IC50 of 31 nM, potential for anticancer and immunomodulation.Fórmula:C24H27F3N8O3Pureza:99.76%Forma y color:SolidPeso molecular:532.52Ref: TM-T11412
1mg105,00€5mg250,00€1mL*10mM (DMSO)283,00€10mg393,00€25mg635,00€50mg944,00€100mg1.254,00€TG2-IN-3h
CAS:TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitorFórmula:C21H26N4O4SPureza:99.34% - 99.76%Forma y color:SolidPeso molecular:430.52TG-2-IN-1
CAS:TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].Fórmula:C8H13ClN2OSPureza:98.43%Forma y color:SolidPeso molecular:220.72UPGL00004
CAS:UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.Fórmula:C25H26N8O2S2Pureza:97.93%Forma y color:SolidPeso molecular:534.66Sirpiglenastat
CAS:Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.Fórmula:C22H27N5O5Pureza:98.01% - 98.37%Forma y color:SolidPeso molecular:441.48KCC009
CAS:KCC009 is a potent and selective Transglutaminase 2 Inhibitor.Fórmula:C21H22BrN3O5Forma y color:SolidPeso molecular:476.32ZED-1227
CAS:ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Diseas
Fórmula:C26H36N6O6Pureza:99.04%Forma y color:SolidPeso molecular:528.6
