Células madre
Los inhibidores de células madre son compuestos que actúan específicamente sobre las células madre y sus vías de señalización, afectando su capacidad para autorrenovarse y diferenciarse. Estos inhibidores son cruciales en la investigación centrada en controlar el comportamiento de las células madre, comprender los procesos de desarrollo y desarrollar terapias para enfermedades como el cáncer, donde se cree que las células madre juegan un papel clave. En CymitQuimica, ofrecemos una variedad de inhibidores de células madre para apoyar su investigación en medicina regenerativa, biología del desarrollo y oncología.
Se han encontrado 484 productos de "Células madre"
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CK2α-IN-1
CAS:<p>CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can</p>Fórmula:C16H11N3O4SPureza:98%Forma y color:SolidPeso molecular:341.34ELN318463 racemate
CAS:<p>ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.</p>Fórmula:C19H20BrClN2O3SPureza:99.69%Forma y color:SolidPeso molecular:471.8JAK-IN-10
CAS:<p>JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.</p>Fórmula:C20H18FN5O3SPureza:99.53%Forma y color:SolidPeso molecular:427.45H-1152
CAS:<p>H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).</p>Fórmula:C16H21N3O2SPureza:98%Forma y color:SolidPeso molecular:319.42Wnt pathway activator 2
CAS:<p>Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.</p>Fórmula:C17H15NO4Pureza:99.41%Forma y color:SolidPeso molecular:297.31JA310
CAS:<p>JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].</p>Fórmula:C17H19N7OForma y color:SolidPeso molecular:337.38γ-secretase modulator 1
CAS:<p>gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies about the treatment of Alzheimer's disease.</p>Fórmula:C24H24N4OSPureza:99.75% - 99.96%Forma y color:SolidPeso molecular:416.54TEAD-IN-2
CAS:<p>TEAD-IN-2 is a potent and bifunctional TEAD inhibitor to induce TEAD protein degradation via the ubiquitination pathway, with anticancer potential.</p>Fórmula:C16H18BrF3N2OForma y color:SolidPeso molecular:391.23GSK-3β inhibitor 12
CAS:<p>GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3β</p>Fórmula:C14H13N3OSPureza:98.58%Forma y color:SolidPeso molecular:271.34JAK3/BTK-IN-1
CAS:<p>JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important</p>Fórmula:C25H28N8OPureza:97.89%Forma y color:SolidPeso molecular:456.54CAY10746
CAS:<p>CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.</p>Fórmula:C26H23N3O5Pureza:99.04%Forma y color:SolidPeso molecular:457.48PI-828
CAS:<p>PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.</p>Fórmula:C19H18N2O3Pureza:99.95%Forma y color:SolidPeso molecular:322.36EHT 1610
CAS:<p>EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.</p>Fórmula:C18H14FN5O2SPureza:98.59%Forma y color:SolidPeso molecular:383.4Miclxin
CAS:<p>Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potent</p>Fórmula:C26H27N5O2Pureza:99.17% - 99.99%Forma y color:SolidPeso molecular:441.52CRT0066854 hydrochloride
CAS:<p>CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.</p>Fórmula:C24H27Cl2N5SPureza:99.63%Forma y color:SolidPeso molecular:488.48CID-5056270
CAS:<p>CID-5056270 has anticancer activity and can inhibit lung cancer, anal cancer, bladder cancer, cervical cancer, vulvar cancer, penile cancer, Burkitt's lymphoma</p>Fórmula:C17H13N3O3SPureza:99.6%Forma y color:SolidPeso molecular:339.37DIF-3
CAS:<p>DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.</p>Fórmula:C13H17ClO4Pureza:99.57%Forma y color:SolidPeso molecular:272.72AS 1892802
CAS:<p>AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.</p>Fórmula:C20H19N3O2Pureza:99.86%Forma y color:SolidPeso molecular:333.38GSK-3β inhibitor 11
CAS:<p>GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM.</p>Fórmula:C20H15N3O4SPureza:97.33%Forma y color:SolidPeso molecular:393.42XL413 xHCl
CAS:<p>BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215</p>Fórmula:C14H12ClN3O2·xHClPureza:99.37% - 99.67%Forma y color:SolidPeso molecular:326.18
