Células madre
Los inhibidores de células madre son compuestos que actúan específicamente sobre las células madre y sus vías de señalización, afectando su capacidad para autorrenovarse y diferenciarse. Estos inhibidores son cruciales en la investigación centrada en controlar el comportamiento de las células madre, comprender los procesos de desarrollo y desarrollar terapias para enfermedades como el cáncer, donde se cree que las células madre juegan un papel clave. En CymitQuimica, ofrecemos una variedad de inhibidores de células madre para apoyar su investigación en medicina regenerativa, biología del desarrollo y oncología.
Se han encontrado 484 productos de "Células madre"
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TP0427736
CAS:<p>TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x > ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.</p>Fórmula:C14H10N4S2Pureza:97.26%Forma y color:SolidPeso molecular:298.39Stafib-2
CAS:<p>Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM,</p>Fórmula:C28H26N2O12P2Pureza:98.48%Forma y color:SolidPeso molecular:644.46GSK-3β inhibitor 8
CAS:<p>GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine</p>Fórmula:C20H20ClN5OSPureza:98.46%Forma y color:SolidPeso molecular:413.92JAK kinase-IN-1
CAS:<p>JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32</p>Fórmula:C17H19F2N7OSPureza:98%Forma y color:SolidPeso molecular:407.44ROCK-IN-8
CAS:<p>ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research,</p>Fórmula:C30H25FN4O4SPureza:98%Forma y color:SolidPeso molecular:556.61Casein kinase 1δ-IN-10
CAS:<p>Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).</p>Fórmula:C21H17N3O3Pureza:98%Forma y color:SolidPeso molecular:359.38JW 67
CAS:<p>JW 67 is an inhibitor of canonical Wnt pathway signaling.</p>Fórmula:C21H18N2O6Pureza:99.02%Forma y color:SolidPeso molecular:394.38ABBV-712
CAS:<p>ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseases</p>Fórmula:C24H28N4O5Pureza:98%Forma y color:SolidPeso molecular:452.5JAK2-IN-4
CAS:<p>JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.</p>Fórmula:C23H27N5O4SPureza:98%Forma y color:SolidPeso molecular:469.56DT-6
CAS:<p>DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing</p>Fórmula:C89H130N20O29S2Pureza:98%Forma y color:SolidPeso molecular:2008.23Casein Kinase II Inhibitor IV
CAS:<p>Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.</p>Fórmula:C24H23N5O3Pureza:99.65% - 99.75%Forma y color:SolidPeso molecular:429.47A 1070722
CAS:<p>A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, potential brain GSK-3 PET radiotracer.</p>Fórmula:C17H13F3N4O2Pureza:99.9%Forma y color:SolidPeso molecular:362.31ROCK2-IN-2
CAS:<p>ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).</p>Fórmula:C18H12N6OSPureza:99.65%Forma y color:SolidPeso molecular:360.39YAP-TEAD-IN-2
CAS:<p>YAP-TEAD-IN-2 (compound 6) serves as a potent inhibitor of the YAP-TEAD protein-protein interaction (PPI), demonstrating an inhibitory concentration 50 (IC50)</p>Fórmula:C25H24ClFN2O4Pureza:98%Forma y color:SolidPeso molecular:470.92Antitumor agent-73
CAS:<p>Antitumor Agent-73, derived from Diosgenin, blocks STAT3 and activates Pdia3, showing strong cancer cell line efficacy.</p>Fórmula:C50H82BrO4PPureza:98%Forma y color:SolidPeso molecular:858.06inS3-54A18
CAS:<p>inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects.</p>Fórmula:C23H16ClNO2Pureza:99.68%Forma y color:SolidPeso molecular:373.83ROCK2-IN-6 hydrochloride
CAS:<p>ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂，适用于研究ROCK介导的疾病、自身免疫性病症与炎症。</p>Fórmula:C26H22ClF2N7OPureza:98%Forma y color:SolidPeso molecular:521.95TGFβ-IN-5
CAS:<p>TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.</p>Fórmula:C20H16N4Pureza:99.29% - 99.5%Forma y color:SolidPeso molecular:312.37STAT6-IN-3
CAS:<p>STAT6-IN-3 (Compound 18a) serves as an inhibitor of STAT6 with an IC50 value of 44 nM, specifically targeting the Src Homology 2 (SH2) domain.</p>Fórmula:C32H35IN3O7PPureza:98%Forma y color:SolidPeso molecular:731.51Casein kinase 1δ-IN-4
CAS:<p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>Fórmula:C16H12N6SPureza:98%Forma y color:SolidPeso molecular:320.37
