Células madre
Los inhibidores de células madre son compuestos que actúan específicamente sobre las células madre y sus vías de señalización, afectando su capacidad para autorrenovarse y diferenciarse. Estos inhibidores son cruciales en la investigación centrada en controlar el comportamiento de las células madre, comprender los procesos de desarrollo y desarrollar terapias para enfermedades como el cáncer, donde se cree que las células madre juegan un papel clave. En CymitQuimica, ofrecemos una variedad de inhibidores de células madre para apoyar su investigación en medicina regenerativa, biología del desarrollo y oncología.
Se han encontrado 484 productos de "Células madre"
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BD750
CAS:<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Fórmula:C14H13N3OSPureza:99.02%Forma y color:SolidPeso molecular:271.34BMS986260
CAS:<p>BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).</p>Fórmula:C18H12ClFN6OPureza:97.67%Forma y color:SolidPeso molecular:382.78LY900009
CAS:<p>LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.</p>Fórmula:C23H27N3O4Pureza:97.07%Forma y color:SolidPeso molecular:409.48BMP signaling agonist sb4
CAS:<p>BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)</p>Fórmula:C14H10BrNOSPureza:99.48% - 99.805%Forma y color:SolidPeso molecular:320.2IMR-1
CAS:<p>IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.</p>Fórmula:C15H15NO5S2Pureza:97.96% - 98.38%Forma y color:SolidPeso molecular:353.41Fz7-21
CAS:<p>Fz7-21, a peptide antagonist of FZD7, inhibits Wnt/β-catenin signaling (IC50=50-100nM) in cells with WNT3A.</p>Fórmula:C83H114N18O23S2Pureza:99.8%Forma y color:SolidPeso molecular:1796.03I3MT-3
CAS:<p>I3MT-3 (HMPSNE) is a selective inhibitor of 3MST, targeting active site cysteine residues and permeating cell membranes.</p>Fórmula:C17H14N2O2SPureza:99.76%Forma y color:SolidPeso molecular:310.37TTP 22
CAS:<p>TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.</p>Fórmula:C16H14N2O2S2Pureza:97.08% - 97.78%Forma y color:SolidPeso molecular:330.42RKI-1447
CAS:<p>RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.</p>Fórmula:C16H14N4O2SPureza:98% - 99.73%Forma y color:SolidPeso molecular:326.37KY19382
CAS:<p>KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may help in metabolic disease research.</p>Fórmula:C17H11Cl2N3O2Pureza:98.06%Forma y color:SolidPeso molecular:360.19DMAT
CAS:<p>DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).</p>Fórmula:C9H7Br4N3Pureza:99.48%Forma y color:SolidPeso molecular:476.79JANEX-1
CAS:<p>JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.</p>Fórmula:C16H15N3O3Pureza:98% - 99.81%Forma y color:SolidPeso molecular:297.31KYA1797K
CAS:<p>KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.</p>Fórmula:C17H11N2O6S2·KPureza:97.57% - 99.33%Forma y color:SolidPeso molecular:442.51ML116
CAS:<p>ML116 is a potent and selective STAT3 inhibitor.</p>Fórmula:C18H19N3SPureza:99.49%Forma y color:SolidPeso molecular:309.43LY2090314
CAS:<p>LY2090314, a potent GSK-3α/β blocker (IC50: 1.5/0.9 nM), could boost platinum chemo. Tested in leukemia and advanced cancers.</p>Fórmula:C28H25FN6O3Pureza:99.21% - 99.91%Forma y color:SolidPeso molecular:512.53FLI-06
CAS:FLI-06 is a Notch signaling inhibitor (EC50: 2.3 μM).Fórmula:C25H30N2O5Pureza:99.81% - ≥98%Forma y color:SolidPeso molecular:438.52SAR407899 hydrochloride
CAS:<p>SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and</p>Fórmula:C14H17ClN2O2Pureza:99.15%Forma y color:SolidPeso molecular:280.75MYF-01-37
CAS:<p>MYF-01-37 (1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one) is a novel covalent TEAD inhibitor.</p>Fórmula:C15H17F3N2OPureza:99.46% - 99.5%Forma y color:SolidPeso molecular:298.3SRI-011381 hydrochloride
CAS:<p>SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.</p>Fórmula:C20H32ClN3OPureza:99.32% - 99.41%Forma y color:SolidPeso molecular:365.94Y-27632 dihydrochloride
CAS:<p>View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.</p>Fórmula:C14H21N3O·2HClPureza:97.96% - 99.98%Forma y color:SolidPeso molecular:320.26
