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Células madre

Células madre

Los inhibidores de células madre son compuestos que actúan específicamente sobre las células madre y sus vías de señalización, afectando su capacidad para autorrenovarse y diferenciarse. Estos inhibidores son cruciales en la investigación centrada en controlar el comportamiento de las células madre, comprender los procesos de desarrollo y desarrollar terapias para enfermedades como el cáncer, donde se cree que las células madre juegan un papel clave. En CymitQuimica, ofrecemos una variedad de inhibidores de células madre para apoyar su investigación en medicina regenerativa, biología del desarrollo y oncología.

Se han encontrado 486 productos de "Células madre"

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  • Brepocitinib P-Tosylate

    CAS:
    <p>Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).</p>
    Fórmula:C25H29F2N7O4S
    Pureza:99.82% - 99.97%
    Forma y color:Solid
    Peso molecular:561.6
  • CWP232228

    CAS:
    <p>CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.</p>
    Fórmula:C33H34N7Na2O7P
    Pureza:98.87%
    Forma y color:Solid
    Peso molecular:717.63
  • Garetosmab

    CAS:
    <p>Garetosmab (REGN 2477), a human IgG4 monoclonal antibody, inhibits activin A for potential cancer treatment and FOP study.</p>
    Pureza:> 95% - > 95%
    Forma y color:Liquid
    Peso molecular:146 kDa
  • ROCK inhibitor-2

    CAS:
    <p>ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).</p>
    Fórmula:C21H20N2O2
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:332.4
  • Golidocitinib

    CAS:
    <p>Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: &gt;14.7, &gt;30 μM).</p>
    Fórmula:C25H31N9O2
    Pureza:98.87% - 99.88%
    Forma y color:Solid
    Peso molecular:489.57
  • NGP555

    CAS:
    <p>NGP555 is a modulator of γ-secretase.</p>
    Fórmula:C23H23FN4S
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:406.52
  • Silmitasertib sodium salt

    CAS:
    <p>Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).</p>
    Fórmula:C19H11ClN3NaO2
    Pureza:99.49% - 99.62%
    Forma y color:Solid
    Peso molecular:371.75
  • JW74

    CAS:
    <p>JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).</p>
    Fórmula:C24H20N6O2S
    Pureza:95.00%
    Forma y color:Solid
    Peso molecular:456.52
  • 1(R),2(S)-epoxy Cannabidiol

    CAS:
    <p>1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.</p>
    Fórmula:C21H30O3
    Forma y color:Solid
    Peso molecular:330.46
  • GSK-3β inhibitor 1

    CAS:
    <p>GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.</p>
    Fórmula:C14H10N2O
    Pureza:99.40%
    Forma y color:Solid
    Peso molecular:222.24
  • Wnt/β-catenin agonist 3

    CAS:
    <p>Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.</p>
    Fórmula:C16H15ClN4O2
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:330.77
  • Wnt/Hedgehog/Notch Compound Library


    <p>A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;</p>
    Forma y color:Odour Solid
  • Wnt pathway inhibitor 3

    CAS:
    <p>Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studies</p>
    Fórmula:C21H17BrN2O5
    Pureza:99.69%
    Forma y color:Soild
    Peso molecular:457.27
  • Jagged-1 (188-204)

    CAS:
    <p>Jagged-1 (188-204)is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin.</p>
    Fórmula:C93H127N25O26S3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2107.4
  • YAP-TEAD-IN-1 acetate


    <p>YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.</p>
    Fórmula:C95H148ClN23O23S2
    Pureza:98.11% - 99.57%
    Forma y color:Soild
    Peso molecular:2079.92
  • Carboxylesterase-IN-2

    CAS:
    <p>Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 &lt;= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.</p>
    Fórmula:C13H12N4OS
    Pureza:99.92%
    Forma y color:Soild
    Peso molecular:272.33
  • Casein kinase 1δ-IN-6

    CAS:
    <p>CK1δ-IN-6: potent, selective CK-1δ inhibitor, IC50 23 nM, neuroprotective, anti-inflammatory, for neurodegenerative research.</p>
    Fórmula:C16H10ClF3N2OS
    Pureza:99%
    Forma y color:Soild
    Peso molecular:370.78
  • ABC99

    CAS:
    <p>ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.</p>
    Fórmula:C22H21ClN4O5
    Pureza:99.89%
    Forma y color:Soild
    Peso molecular:456.88
  • WAY-656935

    CAS:
    <p>WAY-656935 inhibits ROCK.</p>
    Fórmula:C20H28ClN3O3S
    Pureza:98.1%
    Forma y color:Solid
    Peso molecular:425.97
  • Epigenetics Compound Library


    <p>Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new</p>
    Forma y color:Odour Solid