Tie-2
Los inhibidores de Tie-2 son compuestos que se dirigen al receptor Tie-2, una tirosina quinasa involucrada en la angiogénesis y la integridad vascular. La señalización de Tie-2 es crucial para el mantenimiento de los vasos sanguíneos, y su desregulación está asociada con el cáncer y las enfermedades vasculares. En CymitQuimica, ofrecemos inhibidores de Tie-2 para apoyar su investigación en angiogénesis, biología vascular y terapias contra el cáncer dirigidas.
Se han encontrado 24 productos para "Tie-2".
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CE-245677
CAS:CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases. With a cellular IC50s of 4.7 and 1 nM.Fórmula:C24H22Cl2N6O3Pureza:98.99% - 99.23%Forma y color:SolidPeso molecular:513.376TIE2 Protein, Human, Recombinant (aa 23-745, His)
TIE2 Protein, Human, Recombinant (aa 23-745, His) is expressed in HEK293 mammalian cells with C-6xHis tag.Forma y color:White Lyophilized PowderPeso molecular:100-120 KDa (reducing condition)Anti-TIE2 Antibody-FITC (9U826)
Anti-TIE2 Antibody-FITC (9U826) is a FITC-conjugated Rabbit antibody targeting TIE2. Anti-TIE2 Antibody-FITC (9U826) can be used in FCM.Forma y color:Odour LiquidAnti-TIE2 Antibody (9U826)
Anti-TIE2 Antibody (9U826) is a Rabbit antibody targeting TIE2. Anti-TIE2 Antibody (9U826) can be used in ELISA(Cap),FCM,ICC/IF.Forma y color:Odour LiquidAnti-TIE2 Antibody-PE (1E654)
Anti-TIE2 Antibody-PE (1E654) is a PE-conjugated Mouse antibody targeting TIE2. Anti-TIE2 Antibody-PE (1E654) can be used in FCM.Forma y color:Odour LiquidAnti-TIE2 Antibody (7A105)
Anti-TIE2 Antibody (7A105) is a Mouse antibody targeting TIE2. Anti-TIE2 Antibody (7A105) can be used in ELISA.Forma y color:Odour LiquidAnti-TIE2 Antibody-PE (9U826)
Anti-TIE2 Antibody-PE (9U826) is a PE-conjugated Rabbit antibody targeting TIE2. Anti-TIE2 Antibody-PE (9U826) can be used in FCM.Forma y color:Odour LiquidAnti-TIE2 Antibody-FITC (1E654)
Anti-TIE2 Antibody-FITC (1E654) is a FITC-conjugated Mouse antibody targeting TIE2. Anti-TIE2 Antibody-FITC (1E654) can be used in FCM.Forma y color:Odour LiquidTIE2 Protein, Human, Recombinant (hFc)
TIE2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Forma y color:White Lyophilized PowderPeso molecular:120-150 KDa (reducing condition)TIE2 Protein, Mouse, Recombinant (His), Biotinylated
TIE2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:82.03 kDa (predicted); 88.1 kDa (reducing conditions)TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST)
TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST) is expressed in Baculovirus insect cells with His and GST tag.Forma y color:Lyophilized PowderPeso molecular:68.2kDa (predicted); 68 kDa (reducing conditions)TIE2 Protein, Mouse, Recombinant (hFc)
TIE2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:107.7 kDa (predicted)Anti-TIE2 Antibody-APC (9U826)
Anti-TIE2 Antibody-APC (9U826) is a APC-conjugated Rabbit antibody targeting TIE2. Anti-TIE2 Antibody-APC (9U826) can be used in FCM.Forma y color:Odour LiquidAnti-TIE2 Antibody-APC (1E654)
Anti-TIE2 Antibody-APC (1E654) is a APC-conjugated Mouse antibody targeting TIE2. Anti-TIE2 Antibody-APC (1E654) can be used in FCM.Forma y color:Odour LiquidAnti-Human TIE2/CD202b Antibody
Anti-TIE2/CD202b Antibody is a mAb targeting CD202b that inhibits vascular development and tumor angiogenesis by blocking angiopoietin signaling.Peso molecular:146.34 kDa (Predicted)Razuprotafib
CAS:Razuprotafib (AKB-9778) inhibits HPTPß (IC50: 50 nM), activates Tie-2, and guards against acute kidney injury.Fórmula:C26H26N4O6S3Pureza:98.53% - 99.76%Forma y color:White SolidPeso molecular:586.703Tie2 kinase inhibitor 1
CAS:Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effectiveFórmula:C26H21N3O2SPureza:99.51%Forma y color:SolidPeso molecular:439.529Vanucizumab
CAS:Vanucizumab is a bispecific humanised monoclonal antibody that simultaneously inhibits the receptor interactions of VEGF-A and Angiopoietin-2 (Ang-2)Pureza:95%Forma y color:LiquidPeso molecular:146.89 kDa (Predicted)CE-245677 mesylate
CAS:CE-245677 mesylate is a selective Tie2 kinase inhibitor with oral activity and potential anti-tumor effects, useful in pain research.Fórmula:C25H26Cl2N6O6SPureza:99.42%Forma y color:SolidPeso molecular:609.48ASKG-712
ASKG-712 (AM712) is a recombinant humanized monoclonal antibody (mAb) combined with an Ang-2 antagonist peptide fusion protein. It is utilized in research focused on wet age-related macular degeneration and diabetic macular edema.
