HER
Los inhibidores de HER son compuestos que bloquean la actividad de los receptores del factor de crecimiento epidérmico humano, en particular HER2, que está sobreexpresado en ciertos cánceres de mama y otras malignidades. La inhibición de las vías de señalización de HER es una estrategia clave en las terapias contra el cáncer dirigidas. En CymitQuimica, ofrecemos inhibidores de HER para apoyar su investigación en oncología, terapias dirigidas y señalización celular.
Se han encontrado 12 productos para "HER".
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Panomifene HCl
CAS:Panomifene HCl is a selective anti-estrogenic compound with antitumor activity for the treatment of breast cancer.Fórmula:C25H25ClF3NO2Pureza:99.53%Forma y color:SolidPeso molecular:463.92Trastuzumab β
CAS:Trastuzumab beta (ABP 980), a biosimilar McAb, targets HER2 for HER2+ breast and gastric cancer research.Forma y color:LiquidHER2/neu (654-662) GP2 acetate
GP2 acetate, from HER2 (654-662), triggers HLA-A2-restricted T cells to attack epithelial cancers.Fórmula:C44H81N9O13Pureza:98%Forma y color:SolidPeso molecular:944.17Ref: TM-TP1583L
1mg175,00€5mg394,00€10mg590,00€25mg1.060,00€50mg1.591,00€100mg2.387,00€200mg3.580,00€Coprelotamab
CAS:Coprelotamab is a humanized mAb targeting HER2 that inhibits tumor growth by blocking receptor dimerization and mediating ADCC, used for HER2-positive cancer research.Pureza:95%Forma y color:Transparent LiquidABP-102
ABP-102 (CT P72) is a bispecific t-cell adduct (BiTE) that acts as a CD3 modulator and selective HER2 modulator for targeting HER2 overexpressing tumors.Forma y color:Odour LiquidPF04929113
CAS:PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.Fórmula:C25H30F3N5O4Pureza:99.04%Forma y color:SolidPeso molecular:521.53Ref: TM-T6341
1mg37,00€2mg50,00€5mg79,00€1mL*10mM (DMSO)92,00€10mg113,00€25mg177,00€50mg334,00€100mg500,00€PF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Fórmula:C26H34F3N5O7SPureza:99% - 99.46%Forma y color:SolidPeso molecular:617.63Ref: TM-T4342
1mg73,00€2mg95,00€5mg150,00€1mL*10mM (DMSO)220,00€10mg273,00€25mg396,00€50mg583,00€100mg832,00€500mg1.684,00€BMS 599626 2HCl
CAS:BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100Fórmula:C27H29FN8O3Cl2Pureza:99.94%Forma y color:SoildPeso molecular:603.48Zanidatamab
CAS:Zanidatamab (ZW25) is a bispecific, humanized monoclonal antibody that targets two distinct epitopes (ECD2 and ECD4) of the HER2 receptor, exhibiting anti-tumorPureza:95%Forma y color:Transparent LiquidAnbenitamab
CAS:Anbenitamab (KN-026) is a HER2 biparatopic bispecific antibody that exerts potent anti-tumor efficacy by inhibiting HER2 signaling and mediating ADCC.Forma y color:LiquidCinrebafusp alfa
CAS:Cinrebafusp alfa is a CD137/HER2 bispecific antibody mediating T cell co-stimulation, with potential in HER2-positive solid tumor research.Pureza:95%Forma y color:LiquidHER2-IN-12
CAS:HER2-IN-12 is a selective HER2 inhibitor; blocks autophosphorylation; inhibits signaling; breast cancer research.Fórmula:C17H18BrN5O2SForma y color:SolidPeso molecular:436.33
