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HER

HER

Los inhibidores de HER son compuestos que bloquean la actividad de los receptores del factor de crecimiento epidérmico humano, en particular HER2, que está sobreexpresado en ciertos cánceres de mama y otras malignidades. La inhibición de las vías de señalización de HER es una estrategia clave en las terapias contra el cáncer dirigidas. En CymitQuimica, ofrecemos inhibidores de HER para apoyar su investigación en oncología, terapias dirigidas y señalización celular.

Se han encontrado 10 productos para "HER".

  • Panomifene HCl
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    Panomifene HCl

    CAS:
    Panomifene HCl is a selective anti-estrogenic compound with antitumor activity for the treatment of breast cancer.
    Fórmula:C25H25ClF3NO2
    Pureza:99.53%
    Forma y color:Solid
    Peso molecular:463.92

    Ref: TM-T33876L

  • HER2/neu (654-662) GP2 acetate
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    HER2/neu (654-662) GP2 acetate

    GP2 acetate, from HER2 (654-662), triggers HLA-A2-restricted T cells to attack epithelial cancers.
    Fórmula:C44H81N9O13
    Pureza:98%
    Forma y color:Solid
    Peso molecular:944.17

    Ref: TM-TP1583L

  • Coprelotamab
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    Coprelotamab

    CAS:
    Coprelotamab is a humanized mAb targeting HER2 that inhibits tumor growth by blocking receptor dimerization and mediating ADCC, used for HER2-positive cancer research.
    Pureza:95%
    Forma y color:Transparent Liquid

    Ref: TM-T80596

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    Trastuzumab-anns

    CAS:
    Trastuzumab-anns is a biosimilar of Herceptin and a monoclonal antibody targeting HER2 that is used for HER2-positive breast cancer and gastric cancer.
    Pureza:95%
    Forma y color:Liquid
    Peso molecular:~150 kDa

    Ref: TM-T76971

  • PF-04929113 Mesylate
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    PF-04929113 Mesylate

    CAS:
    PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37
    Fórmula:C26H34F3N5O7S
    Pureza:99% - 99.46%
    Forma y color:Solid
    Peso molecular:617.638

    Ref: TM-T4342

  • PF04929113
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    PF04929113

    CAS:
    PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.
    Fórmula:C25H30F3N5O4
    Pureza:99.04%
    Forma y color:Solid
    Peso molecular:521.532

    Ref: TM-T6341

  • BMS 599626 2HCl
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    BMS 599626 2HCl

    CAS:
    BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100
    Fórmula:C27H29FN8O3Cl2
    Pureza:99.94%
    Forma y color:Soild
    Peso molecular:603.48

    Ref: TM-T5398

  • Anbenitamab
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    Anbenitamab

    CAS:
    Anbenitamab (KN-026) is a HER2 biparatopic bispecific antibody that exerts potent anti-tumor efficacy by inhibiting HER2 signaling and mediating ADCC.
    Forma y color:Liquid

    Ref: TM-T76905

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    Cinrebafusp alfa

    CAS:
    Cinrebafusp alfa is a CD137/HER2 bispecific antibody mediating T cell co-stimulation, with potential in HER2-positive solid tumor research.
    Pureza:95%
    Forma y color:Liquid

    Ref: TM-T80590

  • HER2-IN-12
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    HER2-IN-12

    CAS:
    HER2-IN-12 is a selective HER2 inhibitor; blocks autophosphorylation; inhibits signaling; breast cancer research.
    Fórmula:C17H18BrN5O2S
    Forma y color:Solid
    Peso molecular:436.33

    Ref: TM-T62487