HER
Los inhibidores de HER son compuestos que bloquean la actividad de los receptores del factor de crecimiento epidérmico humano, en particular HER2, que está sobreexpresado en ciertos cánceres de mama y otras malignidades. La inhibición de las vías de señalización de HER es una estrategia clave en las terapias contra el cáncer dirigidas. En CymitQuimica, ofrecemos inhibidores de HER para apoyar su investigación en oncología, terapias dirigidas y señalización celular.
Se han encontrado 13 productos para "HER".
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Panomifene HCl
CAS:Panomifene HCl is a selective anti-estrogenic compound with antitumor activity for the treatment of breast cancer.Fórmula:C25H25ClF3NO2Pureza:99.53%Forma y color:SolidPeso molecular:463.92HER2/neu (654-662) GP2 acetate
GP2 acetate, from HER2 (654-662), triggers HLA-A2-restricted T cells to attack epithelial cancers.Fórmula:C44H81N9O13Pureza:98%Forma y color:SolidPeso molecular:944.17Ref: TM-TP1583L
1mg181,00€5mg393,00€10mg589,00€25mg1.060,00€50mg1.591,00€100mg2.386,00€200mg3.580,00€Coprelotamab
CAS:Coprelotamab is a humanized mAb targeting HER2 that inhibits tumor growth by blocking receptor dimerization and mediating ADCC, used for HER2-positive cancer research.Pureza:95%Forma y color:Transparent LiquidTrastuzumab-anns
CAS:Trastuzumab-anns is a biosimilar of Herceptin and a monoclonal antibody targeting HER2 that is used for HER2-positive breast cancer and gastric cancer.Pureza:95%Forma y color:LiquidPeso molecular:~150 kDaPF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Fórmula:C26H34F3N5O7SPureza:99% - 99.46%Forma y color:SolidPeso molecular:617.638Ref: TM-T4342
1mg72,00€2mg95,00€5mg150,00€1mL*10mM (DMSO)220,00€10mg272,00€25mg396,00€50mg583,00€100mg832,00€500mg1.683,00€PF04929113
CAS:PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.Fórmula:C25H30F3N5O4Pureza:99.04%Forma y color:SolidPeso molecular:521.532Ref: TM-T6341
1mg36,00€2mg50,00€5mg78,00€1mL*10mM (DMSO)91,00€10mg113,00€25mg184,00€50mg334,00€100mg499,00€BMS 599626 2HCl
CAS:BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100Fórmula:C27H29FN8O3Cl2Pureza:99.94%Forma y color:SoildPeso molecular:603.48Runimotamab
CAS:Runimotamab is a T-cell-engaging bispecific antibody targeting HER2 and CD3 that promotes T-cell-mediated killing of HER2-expressing tumor cells for research on HER2-expressing cancers and tumor spheroid models.Pureza:99%Forma y color:Odour LiquidAnbenitamab
CAS:Anbenitamab (KN-026) is a HER2 biparatopic bispecific antibody that exerts potent anti-tumor efficacy by inhibiting HER2 signaling and mediating ADCC.Forma y color:LiquidCinrebafusp alfa
CAS:Cinrebafusp alfa is a CD137/HER2 bispecific antibody mediating T cell co-stimulation, with potential in HER2-positive solid tumor research.Pureza:95%Forma y color:LiquidCaxmotabart
CAS:Caxmotabart is a humanized monoclonal antibody targeting ERBB2 (HER2/CD340). Caxmotabart is used for research on HER2-targeted antibody binding assays and tumor biology.Pureza:95%Forma y color:Odour LiquidPeso molecular:~148 kDaNezutatug
CAS:Nezutatug is a humanized monoclonal antibody targeting HER3 which inhibits receptor dimerization and tumor-cell growth for research on HER3 signaling and tumor biology.Pureza:95%Forma y color:LiquidHER2-IN-12
CAS:HER2-IN-12 is a selective HER2 inhibitor; blocks autophosphorylation; inhibits signaling; breast cancer research.Fórmula:C17H18BrN5O2SForma y color:SolidPeso molecular:436.33
