CSF-1R
Los inhibidores de CSF-1R son compuestos que atacan e inhiben el receptor del factor estimulante de colonias 1 (CSF-1R), una tirosina quinasa receptora involucrada en la regulación de macrófagos y otras células inmunitarias. La inhibición de CSF-1R tiene un potencial terapéutico en enfermedades caracterizadas por una actividad excesiva de los macrófagos, como el cáncer, la inflamación y los trastornos autoinmunes. En CymitQuimica, ofrecemos inhibidores de CSF-1R para apoyar su investigación en inmunología, oncología e inflamación.
Se han encontrado 42 productos de "CSF-1R"
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Edicotinib
CAS:<p>Edicotinib (JNJ-527) is a blood-brain permeable, selective CSF-1R inhibitor, with lesser inhibitory effects on KIT and FLT3.Cost-effective and quality-assured.</p>Fórmula:C27H35N5O2Pureza:98.58% - 99.72%Forma y color:SolidPeso molecular:461.6CSF1R-IN-2
CAS:<p>CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).</p>Fórmula:C20H20FN7O2Pureza:99.29%Forma y color:SolidPeso molecular:409.42CSF1R-IN-1
CAS:<p>CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.</p>Fórmula:C25H20F3N5O2Pureza:97.02% - 98.56%Forma y color:SolidPeso molecular:479.45Anti-CSF1R Antibody (8O797)
<p>Anti-CSF1R Antibody (8O797) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (8O797) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-CSF1R Antibody (4Y587)
<p>Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.</p>Forma y color:Odour LiquidPLX647
CAS:<p>PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).</p>Fórmula:C21H17F3N4Pureza:99.38%Forma y color:SolidPeso molecular:382.38CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
<p>CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:83.04 kDa (predicted); 110.87 kDa (reducing conditions)CSF1R Protein, Human, Recombinant (mFc)
<p>CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:81.5 kDa (predicted)CSF1R Protein, Human, Recombinant (His & GST)
<p>CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.</p>Forma y color:Lyophilized PowderPeso molecular:76 kDa (predicted); 75 kDa (reducing conditions)CSF1R Protein, Cynomolgus, Recombinant (hFc)
<p>Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF</p>Forma y color:Lyophilized PowderPeso molecular:105-130 KDa (reducing condition)CSF1R Protein, Mouse, Recombinant (hFc)
<p>CSF1R Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:81.9 kDa (predicted)CSF1R Protein, Human, Recombinant
<p>CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.</p>Forma y color:Lyophilized PowderPeso molecular:55.1 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation)CSF1R Protein, Human, Recombinant (hFc)
<p>CSF1R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:81.2 kDa (predicted)CSF1R Protein, Mouse, Recombinant (His)
<p>CSF1R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:56.8 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation)CSF1R Protein, Mouse, Recombinant (His), Biotinylated
<p>CSF1R Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:56.8 kDa (predicted)CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
<p>CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:SDS-PAGE: 97.7%; SEC-HPLC: 99.7%Forma y color:Lyophilized PowderPeso molecular:56 kDa (predicted); 85-95 kDa (reducing condition, due to glycosylation)CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)
<p>CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:25.3 kDa (predicted)CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
<p>CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:31.1 kDa (predicted)CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
<p>CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:57.76 kDa (predicted); 82.52 kDa (reducing conditions)CSF1R Protein, Cynomolgus, Recombinant (His)
<p>Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF</p>Forma y color:Lyophilized PowderPeso molecular:80-120 KDa (reducing condition)Anti-CSF1R Antibody (5C535)
<p>Anti-CSF1R Antibody (5C535) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (5C535) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-CSF1R Antibody (1R707)
<p>Anti-CSF1R Antibody (1R707) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (1R707) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-CSF1R Antibody (2I506)
<p>Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-CSF1R Antibody-FITC (4Y587)
<p>Anti-CSF1R Antibody-FITC (4Y587) is a FITC-conjugated Mouse antibody targeting CSF1R. Anti-CSF1R Antibody-FITC (4Y587) can be used in FCM.</p>Forma y color:Odour LiquidAnti-CSF1R Antibody (7V18)
<p>Anti-CSF1R Antibody (7V18) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (7V18) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-CSF1R Antibody (5B661)
<p>Anti-CSF1R Antibody (5B661) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (5B661) can be used in ELISA,ELISA(Cap).</p>Forma y color:Odour LiquidPLX5622
CAS:<p>PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.</p>Fórmula:C21H19F2N5OPureza:98% - 99.92%Forma y color:SolidPeso molecular:395.41Sotuletinib
CAS:<p>Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.</p>Fórmula:C20H22N4O3SPureza:97.43% - 99.82%Forma y color:SolidPeso molecular:398.48Ki20227
CAS:<p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Forma y color:SolidPeso molecular:480.54cFMS Receptor Inhibitor II
CAS:<p>cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor</p>Fórmula:C23H20N4OPureza:99.8%Forma y color:SolidPeso molecular:368.43AZD7507
CAS:<p>AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.</p>Fórmula:C23H27FN6O3Pureza:99.55% - 99.78%Forma y color:SolidPeso molecular:454.5PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Forma y color:SolidPeso molecular:419.48GW2580
CAS:<p>GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.</p>Fórmula:C20H22N4O3Pureza:99.48% - >99.99%Forma y color:SolidPeso molecular:366.41OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Fórmula:C22H16F3N3O2SPureza:99.67%Forma y color:SolidPeso molecular:443.44Dovitinib
CAS:<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Fórmula:C21H21FN6OPureza:99.35% - 99.92%Forma y color:SolidPeso molecular:392.43Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Fórmula:C21H18FN5OPureza:98% - 98.24%Forma y color:SolidPeso molecular:375.4Pexidartinib
CAS:<p>Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential</p>Fórmula:C20H15ClF3N5Pureza:98.34% - 99.45%Forma y color:SolidPeso molecular:417.81PRN1371
CAS:<p>PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).</p>Fórmula:C26H30Cl2N6O4Pureza:98.65%Forma y color:SolidPeso molecular:561.46Vimseltinib
CAS:<p>Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).</p>Fórmula:C23H25N7O2Pureza:99.05% - 99.57%Forma y color:SolidPeso molecular:431.49GW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Fórmula:C21H23N7O2S·HClPureza:99.87%Forma y color:SolidPeso molecular:473.98CSF1R Protein, Feline, Recombinant (His & SUMO)
<p>CSF1R Protein, Feline, Recombinant (His & SUMO) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:70.8 kDa (predicted)Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Fórmula:C27H21N3O3Pureza:99.22%Forma y color:SolidPeso molecular:435.47
