CSF-1R
Los inhibidores de CSF-1R son compuestos que atacan e inhiben el receptor del factor estimulante de colonias 1 (CSF-1R), una tirosina quinasa receptora involucrada en la regulación de macrófagos y otras células inmunitarias. La inhibición de CSF-1R tiene un potencial terapéutico en enfermedades caracterizadas por una actividad excesiva de los macrófagos, como el cáncer, la inflamación y los trastornos autoinmunes. En CymitQuimica, ofrecemos inhibidores de CSF-1R para apoyar su investigación en inmunología, oncología e inflamación.
Se han encontrado 42 productos para "CSF-1R".
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Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Forma y color:SolidPeso molecular:480.54PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Forma y color:Yellow SolidPeso molecular:419.48GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Fórmula:C21H23N7O2S·HClPureza:99.87%Forma y color:SolidPeso molecular:473.98PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Fórmula:C26H30Cl2N6O4Pureza:98.65%Forma y color:SolidPeso molecular:561.46PLX5622
CAS:PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.Fórmula:C21H19F2N5OPureza:98% - 99.97%Forma y color:SolidPeso molecular:395.4053Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFórmula:C21H18FN5OPureza:98% - 98.24%Forma y color:White SolidPeso molecular:375.3989Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFórmula:C20H15ClF3N5Pureza:98.34% - 99.45%Forma y color:White SolidPeso molecular:417.815Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Fórmula:C23H25N7O2Pureza:99.05% - 99.57%Forma y color:SolidPeso molecular:431.4903AZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Fórmula:C23H27FN6O3Pureza:99.55% - 99.78%Forma y color:SolidPeso molecular:454.4973Sotuletinib
CAS:Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Fórmula:C20H22N4O3SPureza:97.43% - 99.82%Forma y color:Yellow SolidPeso molecular:398.479OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Fórmula:C22H16F3N3O2SPureza:99.67%Forma y color:White SolidPeso molecular:443.442cFMS Receptor Inhibitor II
CAS:cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFórmula:C23H20N4OPureza:99.8%Forma y color:SolidPeso molecular:368.4311GW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Fórmula:C20H22N4O3Pureza:99.48% - >99.99%Forma y color:Yellow SolidPeso molecular:366.41Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Fórmula:C21H21FN6OPureza:99.35% - 99.92%Forma y color:SolidPeso molecular:392.43CSF1R Protein, Feline, Recombinant (His & SUMO)
CSF1R Protein, Feline, Recombinant (His & SUMO) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:70.8 kDa (predicted)CSF1R Protein, Cynomolgus, Recombinant (hFc)
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCFForma y color:Lyophilized PowderPeso molecular:105-130 KDa (reducing condition)CSF1R Protein, Cynomolgus, Recombinant (His)
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCFForma y color:Lyophilized PowderPeso molecular:80-120 KDa (reducing condition)Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Fórmula:C27H21N3O3Pureza:99.22%Forma y color:SolidPeso molecular:435.4739Anti-CSF1R Antibody (8O797)
Anti-CSF1R Antibody (8O797) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (8O797) can be used in ELISA.Forma y color:Odour LiquidAnti-CSF1R Antibody (2I506)
Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.Forma y color:Odour Liquid
