CymitQuimica logo
PYK2

PYK2

Los inhibidores de PYK2 son compuestos que inhiben la quinasa tirosina rica en prolina 2 (PYK2), una tirosina quinasa no receptora involucrada en procesos celulares como la adhesión, migración y supervivencia. PYK2 está implicada en la metástasis del cáncer y trastornos neurológicos. En CymitQuimica, ofrecemos inhibidores de PYK2 para apoyar su investigación en metástasis del cáncer, neurobiología y señalización celular.

Se han encontrado 7 productos de "PYK2"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
  • BT-Amide
    Targetmol
    + Info

    BT-Amide

    <p>BT-Amide is an orally active Pyk2 kinase (Pyk2kinase) inhibitor with an IC50 of 44.69 nM. It prevents glucocorticoid-induced bone loss and demonstrates bone-protective activity in C57BL/6 mice.</p>
    Fórmula:C29H38ClN7O11P2
    Forma y color:Solid
    Peso molecular:758.053

    Ref: TM-T204768

  • PF-562271 besylate
    Targetmol
    + Info

    PF-562271 besylate

    CAS:
    <p>PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.</p>
    Fórmula:C21H20F3N7O3S·C6H6O3S
    Pureza:97.65% - 99.01%
    Forma y color:Solid
    Peso molecular:665.66

    Ref: TM-T6177

  • PF-431396
    Targetmol
    + Info

    PF-431396

    CAS:
    <p>PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).</p>
    Fórmula:C22H21F3N6O3S
    Pureza:98.83% - 99.82%
    Forma y color:Solid
    Peso molecular:506.5

    Ref: TM-T2314

  • PF-562271 hydrochloride
    Targetmol
    + Info

    PF-562271 hydrochloride

    CAS:
    <p>PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.</p>
    Fórmula:C21H20F3N7O3SHCl
    Pureza:97.08%
    Forma y color:Solid
    Peso molecular:543.95

    Ref: TM-T21768

  • PF-562271
    Targetmol
    + Info

    PF-562271

    CAS:
    <p>PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).</p>
    Fórmula:C21H20F3N7O3S
    Pureza:97.17% - >99.99%
    Forma y color:Solid
    Peso molecular:507.49

    Ref: TM-T2465

  • NVP-TAE 226
    Targetmol
    + Info

    NVP-TAE 226

    CAS:
    <p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>
    Fórmula:C23H25ClN6O3
    Pureza:98.07% - 98.78%
    Forma y color:Solid
    Peso molecular:468.94

    Ref: TM-T1918

  • PF-4618433
    Targetmol
    + Info

    PF-4618433

    CAS:
    <p>PF-4618433 is a selective PYK2 inhibitor with osteogenic activity.</p>
    Fórmula:C24H27N7O2
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:445.52

    Ref: TM-T22397