c-Kit
Los inhibidores de c-Kit son compuestos que bloquean la actividad del Receptor del Factor de Células Madre (c-Kit), una tirosina quinasa que desempeña un papel crucial en la supervivencia, proliferación y diferenciación celular, particularmente en células hematopoyéticas. Las mutaciones en c-Kit están vinculadas a varios tipos de cáncer, incluidos los tumores del estroma gastrointestinal (GIST) y la leucemia. En CymitQuimica, ofrecemos inhibidores de c-Kit para apoyar su investigación en oncología, hematología y biología de células madre.
Se han encontrado 117 productos de "c-Kit"
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Anti-C-Kit Antibody (6X205)
Anti-C-Kit Antibody (6X205) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (6X205) can be used in ELISA.Forma y color:Odour LiquidAnti-C-Kit Antibody (3B930)
Anti-C-Kit Antibody (3B930) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3B930) can be used in WB,ELISA,IP.Forma y color:Odour LiquidAnti-C-Kit Antibody-PE (1R766)
Anti-C-Kit Antibody-PE (1R766) is a PE-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-PE (1R766) can be used in FCM.Forma y color:Odour LiquidDovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Fórmula:C21H21FN6OPureza:99.35% - 99.92%Forma y color:SolidPeso molecular:392.43ISCK03
CAS:ISCK03 is a selective SCF/c-Kit inhibitor.Fórmula:C19H21N3O2SPureza:98.39%Forma y color:SolidPeso molecular:355.45JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Fórmula:C15H17ClN6O3Pureza:97.08%Forma y color:SolidPeso molecular:364.79Ref: TM-T22349
1mg38,00€5mg78,00€10mg103,00€25mg172,00€50mg250,00€100mg338,00€200mg464,00€1mL*10mM (DMSO)84,00€OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Fórmula:C22H16F3N3O2SPureza:99.67%Forma y color:SolidPeso molecular:443.44Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Fórmula:C28H30N6OSPureza:97.56% - >99.99%Forma y color:SolidPeso molecular:498.64Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Fórmula:C22H28FN4O6PPureza:98.56%Forma y color:SolidPeso molecular:494.45BLU-263
CAS:BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Fórmula:C27H29FN10OPureza:99.01% - 99.67%Forma y color:SolidPeso molecular:528.58Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.62%Forma y color:SolidPeso molecular:510.36Ref: TM-T8482
1mg74,00€2mg97,00€5mg165,00€10mg274,00€25mg432,00€50mg692,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)202,00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Fórmula:C23H27FN4O4Pureza:98.13%Forma y color:SolidPeso molecular:442.48Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Fórmula:C26H27FN10Pureza:96.59% - 99.7%Forma y color:SolidPeso molecular:498.56Ref: TM-T5109
1mg38,00€5mg80,00€10mg120,00€25mg235,00€50mg354,00€100mg588,00€200mg833,00€1mL*10mM (DMSO)175,00€Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Fórmula:C20H17F3N4O3Pureza:99.34%Forma y color:SolidPeso molecular:418.37Ref: TM-T4191
1mg37,00€2mg52,00€5mg79,00€10mg101,00€25mg177,00€50mg268,00€100mg385,00€1mL*10mM (DMSO)87,00€Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Forma y color:SolidPeso molecular:480.54Ref: TM-T4315
1mg44,00€5mg90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€1mL*10mM (DMSO)90,00€Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Fórmula:C29H29F3N8OPureza:99.39% - 99.95%Forma y color:SolidPeso molecular:562.59Ref: TM-T4320
1mg34,00€5mg63,00€10mg82,00€25mg120,00€50mg155,00€100mg259,00€200mg388,00€500mg642,00€1mL*10mM (DMSO)82,00€AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Fórmula:C24H25N5O4Pureza:97.71% - 98.37%Forma y color:SolidPeso molecular:447.49AZD3229 Tosylate
CAS:AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinalFórmula:C31H34FN7O6SForma y color:SolidPeso molecular:651.71Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Forma y color:SolidPeso molecular:570.64Ref: TM-T3211
1mg49,00€5mg84,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€1mL*10mM (DMSO)90,00€Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Fórmula:C24H27FN6O4Pureza:99.54% - 99.77%Forma y color:SolidPeso molecular:482.51Ref: TM-T7104
5mg49,00€10mg74,00€25mg122,00€50mg202,00€100mg339,00€200mg507,00€500mg800,00€1mL*10mM (DMSO)54,00€
