Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1424 productos de "Autofagia"
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JMS-17-2 hydrochloride
CAS:<p>JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.</p>Fórmula:C25H27Cl2N3OForma y color:SolidPeso molecular:456.41Brevilin A
CAS:<p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>Fórmula:C20H26O5Pureza:99.97% - >99.99%Forma y color:SolidPeso molecular:346.42Tempol
CAS:<p>Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.</p>Fórmula:C9H18NO2Pureza:97% - 99.74%Forma y color:4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesPeso molecular:172.25CHIR-99021
CAS:<p>View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.</p>Fórmula:C22H18Cl2N8Pureza:97.94% - ≥95%Forma y color:SolidPeso molecular:465.34Bergapten
CAS:<p>Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.</p>Fórmula:C12H8O4Pureza:99.48% - ≥95%Forma y color:Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)Peso molecular:216.19Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Fórmula:C31H43N3O8Pureza:99.07% - 99.83%Forma y color:Dark Purple SolidPeso molecular:585.69IOWH-032
CAS:<p>IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.</p>Fórmula:C22H15Br2N3O4Pureza:98.92% - ≥95%Forma y color:SolidPeso molecular:545.18Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Forma y color:White PowderPeso molecular:329.39Dantrolene
CAS:<p>Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.</p>Fórmula:C14H10N4O5Pureza:99.97%Forma y color:Crystals From Aq DimethylformamidePeso molecular:314.25Isorhapontigenin
CAS:<p>Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.</p>Fórmula:C15H14O4Pureza:98.49% - 99.85%Forma y color:Off White Crystals PowerPeso molecular:258.27Pinocembrin
CAS:<p>Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.</p>Fórmula:C15H12O4Pureza:99.61% - >99.99%Forma y color:SolidPeso molecular:256.25MW-150 dihydrochloride dihydrate
CAS:<p>MW-150: selective CNS-penetrant p38α MAPK inhibitor, orally active, Ki 101 nM, blocks MK2 phosphorylation in glia.</p>Fórmula:C24H29Cl2N5O2Forma y color:SolidPeso molecular:490.43Cediranib
CAS:<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Fórmula:C25H27FN4O3Pureza:97.21% - 99.94%Forma y color:SolidPeso molecular:450.51Tubastatin A Hydrochloride
CAS:<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Fórmula:C20H21N3O2·HClPureza:97.24% - 99.15%Forma y color:SolidPeso molecular:371.86Quizartinib
CAS:<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Fórmula:C29H32N6O4SPureza:98% - 99.42%Forma y color:SolidPeso molecular:560.67Apigenin
CAS:<p>Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.</p>Fórmula:C15H10O5Pureza:97.64% - 99.66%Forma y color:Yellow Needles From Aqueous Pyridine SolidPeso molecular:270.24U0126-EtOH
CAS:<p>U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!</p>Fórmula:C18H16N6S2·C2H6OPureza:99.72% - 99.88%Forma y color:SolidPeso molecular:426.6Tenovin-6
CAS:<p>Tenovin-6 is a p53 transcriptional activity agonist.</p>Fórmula:C25H34N4O2SPureza:97.71% - >99.99%Forma y color:SolidPeso molecular:454.63AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Fórmula:C21H21N3O2SPureza:97.24% - 99.83%Forma y color:SolidPeso molecular:379.48U0126
CAS:<p>U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.</p>Fórmula:C18H16N6S2Pureza:99.61%Forma y color:White SolidPeso molecular:380.49Torin 1
CAS:<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Fórmula:C35H28F3N5O2Pureza:98.3% - 99.33%Forma y color:SolidPeso molecular:607.62Ligustilide
CAS:<p>3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.</p>Fórmula:C12H14O2Pureza:96.03% - 98.14%Forma y color:Yellow Brown PowderPeso molecular:190.24Pinosylvin
CAS:<p>Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.</p>Fórmula:C14H12O2Pureza:99.89% - 99.91%Forma y color:SolidPeso molecular:212.24Berbamine dihydrochloride
CAS:<p>Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.</p>Fórmula:C37H42Cl2N2O6Pureza:95% - 99.99%Forma y color:SolidPeso molecular:681.65Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Fórmula:C6H9NO6Pureza:98.16%Forma y color:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecular:191.14Entinostat
CAS:<p>Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H20N4O3Pureza:98% - 99.74%Forma y color:SolidPeso molecular:376.41CCT128930 hydrochloride
CAS:<p>CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.</p>Fórmula:C18H21Cl2N5Pureza:98.55%Forma y color:SolidPeso molecular:378.3Gartanin
CAS:<p>Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and PGC-1α pathways.</p>Fórmula:C23H24O6Pureza:99.64% - 99.85%Forma y color:SolidPeso molecular:396.43KB-R7943 mesylate
CAS:<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Fórmula:C17H21N3O6S2Pureza:99.88% - ≥95%Forma y color:SolidPeso molecular:427.5PTC-209 hydrobromide
CAS:<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Fórmula:C17H13Br2N5OS·HBrPureza:99.91%Forma y color:SolidPeso molecular:576.1Autogramin-1
CAS:<p>Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.</p>Fórmula:C23H27N5O5SPureza:97.69% - 99.25%Forma y color:SolidPeso molecular:485.56XL388
CAS:<p>XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.</p>Fórmula:C23H22FN3O4SPureza:99.39% - 99.53%Forma y color:SolidPeso molecular:455.5NSC 185058
CAS:<p>NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.</p>Fórmula:C11H9N3SPureza:99.27%Forma y color:SolidPeso molecular:215.27PF-543 hydrochloride
CAS:<p>PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2</p>Fórmula:C27H32ClNO4SPureza:98.9% - 99.93%Forma y color:SolidPeso molecular:502.1URMC-099
CAS:<p>URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.</p>Fórmula:C27H27N5Pureza:99.32% - 99.98%Forma y color:SolidPeso molecular:421.54Autocamtide-2-related inhibitory peptide
CAS:<p>Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.</p>Fórmula:C64H116N22O19Pureza:>99.99%Forma y color:SolidPeso molecular:1497.74PF-06447475
CAS:<p>PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.</p>Fórmula:C17H15N5OPureza:98.61% - 99.62%Forma y color:SolidPeso molecular:305.33Onjisaponin B
CAS:<p>Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-</p>Fórmula:C75H112O35Pureza:99.20% - 99.972%Forma y color:SolidPeso molecular:1573.67A-867744
CAS:<p>A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).</p>Fórmula:C20H19ClN2O3SPureza:95.66%Forma y color:SolidPeso molecular:402.89Briciclib
CAS:<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Fórmula:C19H23O10PSPureza:98% - 99.84%Forma y color:SolidPeso molecular:474.42TA-01
CAS:<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Fórmula:C20H12F3N3Pureza:99.55% - 99.94%Forma y color:SolidPeso molecular:351.32PI3Kδ-IN-15
CAS:<p>CAL-101 (Idelalisib) is a selective inhibitor of p110δ; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ.</p>Fórmula:C21H16FN7OPureza:99.61%Forma y color:SolidPeso molecular:401.4Lanatoside C
CAS:<p>Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.</p>Fórmula:C49H76O20Pureza:98.3% - >99.99%Forma y color:SolidPeso molecular:985.12Spautin-1
CAS:<p>Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.</p>Fórmula:C15H11F2N3Pureza:97.69% - 98.99%Forma y color:SolidPeso molecular:271.26Sofalcone
CAS:<p>Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.</p>Fórmula:C27H30O6Pureza:97.55%Forma y color:SolidPeso molecular:450.52Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Forma y color:SolidPeso molecular:516.65Nitroprusside disodium dihydrate
CAS:<p>Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.</p>Fórmula:C5H4FeN6Na2O3Pureza:98%Forma y color:Bright RedPeso molecular:297.95UNC1999
CAS:<p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>Fórmula:C33H43N7O2Pureza:99.19% - >99.99%Forma y color:SolidPeso molecular:569.74SAR405
CAS:<p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>Fórmula:C19H21ClF3N5O2Pureza:99.42% - 99.79%Forma y color:SolidPeso molecular:443.85AZ304
CAS:<p>AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).</p>Fórmula:C27H25N5O2Pureza:99.82%Forma y color:SolidPeso molecular:451.52Ivacaftor
CAS:<p>Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,</p>Fórmula:C24H28N2O3Pureza:99% - 99.98%Forma y color:SolidPeso molecular:392.49α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Fórmula:C10H16OPureza:97.02% - 98.41%Forma y color:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecular:152.23Fasudil dihydrochloride
CAS:<p>Fasudil dihydrochloride (HA-1077/AT877) is a RhoA/ROCK inhibitor with kinase-blocking properties and acts as a vasodilator.</p>Fórmula:C14H19Cl2N3O2SForma y color:SolidPeso molecular:364.29Urolithin A
CAS:<p>Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.</p>Fórmula:C13H8O4Pureza:99.14% - 99.67%Forma y color:SolidPeso molecular:228.2Omipalisib
CAS:<p>Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.</p>Fórmula:C25H17F2N5O3SPureza:98% - 99.8%Forma y color:SolidPeso molecular:505.5Vps34-IN-1
CAS:<p>Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.</p>Fórmula:C21H24ClN7OPureza:97.04%Forma y color:SolidPeso molecular:425.91OSI-027
CAS:<p>OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.</p>Fórmula:C21H22N6O3Pureza:97.42%Forma y color:SolidPeso molecular:406.44Nocodazole
CAS:<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Fórmula:C14H11N3O3SPureza:98% - 99.91%Forma y color:Physical Description White Powder (Ntp 1992)Peso molecular:301.32Atorvastatin hemicalcium trihydrate
CAS:<p>Atorvastatin hemicalcium trihydrate, an oral HMG-CoA reductase inhibitor, lowers blood lipids and inhibits SV-SMC with IC50s: 0.39/2.39 μM.</p>Fórmula:C33H35FN2O5Ca·3H2OForma y color:SolidPeso molecular:632.73Aliskiren hydrochloride
CAS:<p>Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is a selective, orally active, renin inhibitor (IC50: 1.5 nM). Cachexia.</p>Fórmula:C30H54ClN3O6Forma y color:SolidPeso molecular:588.23Nesolicaftor
CAS:<p>Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.</p>Fórmula:C18H18N4O4Pureza:99.79%Forma y color:SolidPeso molecular:354.36SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Fórmula:C14H8N2OPureza:97.63% - 99.82%Forma y color:SolidPeso molecular:220.23XCT790
CAS:<p>XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).</p>Fórmula:C23H13F9N4O3SPureza:99% - 99.61%Forma y color:SolidPeso molecular:596.42Lithocholic acid
CAS:<p>Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!</p>Fórmula:C24H40O3Pureza:99.69% - 99.93%Forma y color:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecular:376.57EIPA
CAS:<p>EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.</p>Fórmula:C11H18ClN7OPureza:96.62% - 99.981%Forma y color:Off-White To Yellow SolidPeso molecular:299.76SBI-0206965
CAS:<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Fórmula:C21H21BrN4O5Pureza:99.13%Forma y color:SolidPeso molecular:489.32Crenolanib
CAS:<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Fórmula:C26H29N5O2Pureza:98.40% - 99.73%Forma y color:SolidPeso molecular:443.544,4'-Dimethoxychalcone
CAS:<p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>Fórmula:C17H16O3Pureza:99.57%Forma y color:SolidPeso molecular:268.31AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Fórmula:C17H14N2O3Pureza:98.6% - 99.39%Forma y color:Yellow SolidPeso molecular:294.3PF-06454589
CAS:<p>PF-06454589 is a potent inhibitor of LRRK2.</p>Fórmula:C14H16N6OPureza:99.06%Forma y color:SolidPeso molecular:284.32Lumacaftor
CAS:<p>Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.</p>Fórmula:C24H18F2N2O5Pureza:99.48% - 99.68%Forma y color:SolidPeso molecular:452.41ULK-101
CAS:<p>ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.</p>Fórmula:C22H16F4N4OSPureza:97.55% - 99.94%Forma y color:SolidPeso molecular:460.45Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Fórmula:C20H23BCl2N2O9Pureza:98.37% - >99.99%Forma y color:SolidPeso molecular:517.12Regorafenib mesylate
CAS:<p>Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.</p>Fórmula:C22H19ClF4N4O6SForma y color:SolidPeso molecular:578.92MLN9708 analogues
CAS:<p>MLN2238 inhibits 20S proteasome's β5 site (Ki50=0.93 nM, IC50=3.4 nM), active form of Ixazomib Citrate in solutions/plasma.</p>Fórmula:C20H23BCl2N2O9Pureza:98.24% - 99.23%Forma y color:SolidPeso molecular:517.12Tepotinib hydrochloride(1 : x)
CAS:<p>Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for selected NSCLC patients with METex14</p>Fórmula:C29H29ClN6O2Pureza:99.81%Forma y color:SolidPeso molecular:529.04Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Forma y color:SolidPeso molecular:384.27Trifluoperazine
CAS:<p>Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.</p>Fórmula:C21H24F3N3SPureza:98.3% - 99.46%Forma y color:White To Yellowish Crystalline PowderPeso molecular:407.5E-64
CAS:<p>E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.</p>Fórmula:C15H27N5O5Pureza:98% - 99.95%Forma y color:White SolidPeso molecular:357.41Paeonol
CAS:<p>Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.</p>Fórmula:C9H10O3Pureza:98.55% - 99.56%Forma y color:White To Beige Crystalline PowderPeso molecular:166.17Hoechst 33342 trihydrochloride
CAS:<p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>Fórmula:C27H31Cl3N6OPureza:98.73% - ≥98%Forma y color:SolidPeso molecular:561.93SN-38
CAS:<p>SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).</p>Fórmula:C22H20N2O5Pureza:98% - 99.97%Forma y color:Light-Yellow SolidPeso molecular:392.4Vps34-PIK-III
CAS:<p>Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.</p>Fórmula:C17H17N7Pureza:98.39% - 98.43%Forma y color:SolidPeso molecular:319.36UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Fórmula:C30H31F3N8O3SPureza:98.72% - 99.52%Forma y color:SolidPeso molecular:640.68LYS01
CAS:<p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>Fórmula:C23H23Cl2N5Pureza:98.28%Forma y color:SolidPeso molecular:440.37Rottlerin
CAS:<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Fórmula:C30H28O8Pureza:97.41% - 99.44%Forma y color:Orange To Brown PowderPeso molecular:516.54Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Fórmula:C20H15Cl3N2OS·HNO3Pureza:98.66% - 99.65%Forma y color:SolidPeso molecular:500.78Meglutol
CAS:<p>Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.</p>Fórmula:C6H10O5Pureza:99.73% - 99.94%Forma y color:SolidPeso molecular:162.14Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Forma y color:SolidPeso molecular:393.89Olaparib
CAS:<p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>Fórmula:C24H23FN4O3Pureza:98% - >99.99%Forma y color:SolidPeso molecular:434.46Azithromycin
CAS:<p>Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!</p>Fórmula:C38H72N2O12Pureza:99.9% - 99.97%Forma y color:White To Off-White Solid CrystallinePeso molecular:748.98MRT68921 dihydrochloride
CAS:<p>MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).</p>Fórmula:C25H36Cl2N6OPureza:98.91% - 99.92%Forma y color:SolidPeso molecular:507.499MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Fórmula:C26H41N3O5Pureza:95% - 99.99%Forma y color:White To Off-White PowderPeso molecular:475.62Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Fórmula:C31H33FN6O3Pureza:99.07% - 99.66%Forma y color:SolidPeso molecular:556.63Clinofibrate
CAS:<p>Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.</p>Fórmula:C28H36O6Pureza:>99.99%Forma y color:White Crystalline PowderPeso molecular:468.58Venetoclax
CAS:<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Fórmula:C45H50ClN7O7SPureza:98.00% - 99.97%Forma y color:SolidPeso molecular:868.44Sevelamer hydrochloride
CAS:<p>Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption</p>Fórmula:(C3H7N·C3H5ClO·HCl)xPureza:98%Forma y color:SolidPeso molecular:186.08Idelalisib
CAS:<p>Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).</p>Fórmula:C22H18FN7OPureza:98% - 99.39%Forma y color:SolidPeso molecular:415.42Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Fórmula:C32H46O8Pureza:97.1% - 99.33%Forma y color:SolidPeso molecular:558.7PATULIN
CAS:<p>Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.</p>Fórmula:C7H6O4Pureza:99.91% - 99.98%Forma y color:Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallinePeso molecular:154.12
