Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1424 productos de "Autofagia"
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Cyclovirobuxine D
CAS:<p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>Fórmula:C26H46N2OPureza:97.78% - 98%Forma y color:SolidPeso molecular:402.66Berberine hydrogen sulphate
CAS:<p>Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.</p>Fórmula:C20H19NO8SPureza:99% - 99.79%Forma y color:Yellow Crystals Off-White To Yellow PowderPeso molecular:433.43Tenovin-1
CAS:<p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>Fórmula:C20H23N3O2SPureza:99.33%Forma y color:SolidPeso molecular:369.48Reversine
CAS:<p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>Fórmula:C21H27N7OPureza:98% - 98.42%Forma y color:SolidPeso molecular:393.49Galangin
CAS:<p>Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.</p>Fórmula:C15H10O5Pureza:98.24% - 99.93%Forma y color:Yellowish Needle-Like CrystalPeso molecular:270.24Gemcitabine hydrochloride
CAS:<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Forma y color:White Crystalline Granular OdorlessPeso molecular:299.66JNJ-42165279
CAS:<p>JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.</p>Fórmula:C18H17ClF2N4O3Pureza:99.67% - 99.88%Forma y color:SolidPeso molecular:410.8Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Fórmula:C29H27F3N6OPureza:98% - 99.60%Forma y color:SolidPeso molecular:532.56Purmorphamine
CAS:<p>Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.</p>Fórmula:C31H32N6O2Pureza:97.19% - 99.48%Forma y color:Light Tan SolidPeso molecular:520.62LC3-mHTT-IN-AN2
CAS:<p>LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.</p>Fórmula:C15H10O4Pureza:98.82% - ≥98%Forma y color:SolidPeso molecular:254.24SAR405
CAS:<p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>Fórmula:C19H21ClF3N5O2Pureza:99.42% - 99.79%Forma y color:SolidPeso molecular:443.85Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Fórmula:C9H10O4Pureza:99.88%Forma y color:White Crystal Or PowderPeso molecular:182.17GSK621
CAS:<p>GSK621 is a specific and potent AMPK activator.</p>Fórmula:C26H20ClN3O5Pureza:97.02% - 97.05%Forma y color:SolidPeso molecular:489.91Regorafenib
CAS:<p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>Fórmula:C21H15ClF4N4O3Pureza:98% - 99.95%Forma y color:SolidPeso molecular:482.82Neflamapimod
CAS:<p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>Fórmula:C19H9Cl2F2N3OSPureza:97.88% - 99.75%Forma y color:SolidPeso molecular:436.26Enalaprilat Dihydrate
CAS:<p>Enalaprilat Dihydrate (MK-422 Dihydrate) （IC50=1.94 nM） is a potent angiotensin-converting enzyme (ACE) inhibitor.</p>Fórmula:C18H24N2O5·2H2OPureza:99.46% - 99.78%Forma y color:SolidPeso molecular:348.43BDO
CAS:<p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>Fórmula:C18H17NO5Pureza:97.76%Forma y color:SolidPeso molecular:327.33Mavorixafor trihydrochloride
CAS:<p>Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.</p>Fórmula:C21H30Cl3N5Pureza:98.00%Forma y color:SolidPeso molecular:458.86Mirdametinib
CAS:<p>Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.</p>Fórmula:C16H14F3IN2O4Pureza:99.11% - 99.63%Forma y color:White PowderPeso molecular:482.19KN-92 phosphate
CAS:<p>KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.</p>Fórmula:C24H28ClN2O7PSPureza:99.86%Forma y color:SolidPeso molecular:554.98WYC-209
CAS:<p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>Fórmula:C20H20N2O3SPureza:99.77%Forma y color:SolidPeso molecular:368.45Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Forma y color:SolidPeso molecular:718.08DBEQ
CAS:<p>DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.</p>Fórmula:C22H20N4Pureza:98.93% - ≥95%Forma y color:SolidPeso molecular:340.42Pseudolaric Acid B
CAS:<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Fórmula:C23H28O8Pureza:98.91% - 99.84%Forma y color:SolidPeso molecular:432.46Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Fórmula:C21H17ClF4N4O4Pureza:99.69%Forma y color:SolidPeso molecular:500.83Oleanolic Acid
CAS:<p>Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.</p>Fórmula:C30H48O3Pureza:97.04% - 98.51%Forma y color:SolidPeso molecular:456.7GW 4064
CAS:<p>GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).</p>Fórmula:C28H22Cl3NO4Pureza:98% - 99.94%Forma y color:SolidPeso molecular:542.84Fangchinoline
CAS:<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Fórmula:C37H40N2O6Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:608.72AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Fórmula:C22H24N4O4Pureza:99.79% - 99.95%Forma y color:SolidPeso molecular:408.45JZL195
CAS:<p>JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.</p>Fórmula:C24H23N3O5Pureza:99.81%Forma y color:SolidPeso molecular:433.46ZSTK474
CAS:<p>PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential</p>Fórmula:C19H21F2N7O2Pureza:98.29% - 99.95%Forma y color:White PowderPeso molecular:417.41Obeticholic Acid
CAS:<p>Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.</p>Fórmula:C26H44O4Pureza:99.88% - 99.97%Forma y color:SolidPeso molecular:420.63Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Forma y color:SolidPeso molecular:432.4BC1618
CAS:<p>BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.</p>Fórmula:C24H24F3NO2Pureza:99.95%Forma y color:SolidPeso molecular:415.45Genipin
CAS:<p>Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.</p>Fórmula:C11H14O5Pureza:99.09% - 99.21%Forma y color:SolidPeso molecular:226.234,4'-Dimethoxychalcone
CAS:<p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>Fórmula:C17H16O3Pureza:99.57%Forma y color:SolidPeso molecular:268.31Typhaneoside
CAS:<p>Typhaneoside (Aervitrin) is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.</p>Fórmula:C34H42O20Pureza:98.92% - 99.95%Forma y color:SolidPeso molecular:770.69sbp-7455
CAS:<p>SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.</p>Fórmula:C16H17F3N4O2Pureza:97.90% - 99.842%Forma y color:SolidPeso molecular:354.33SNX2112
CAS:<p>SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.</p>Fórmula:C23H27F3N4O3Pureza:98.75% - 99.46%Forma y color:SolidPeso molecular:464.48BX795
CAS:<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Fórmula:C23H26IN7O2SPureza:98% - 99.57%Forma y color:SolidPeso molecular:591.47Hoechst 33342 trihydrochloride
CAS:<p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>Fórmula:C27H31Cl3N6OPureza:98.73% - ≥98%Forma y color:SolidPeso molecular:561.93PI-103
CAS:<p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>Fórmula:C19H16N4O3Pureza:97.79% - 99.3%Forma y color:SolidPeso molecular:348.36Rasagiline Mesylate
CAS:<p>Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.</p>Fórmula:C13H17NO3SPureza:99.33%Forma y color:White PowderPeso molecular:267.34Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Fórmula:C18H22O4Pureza:97.82% - 99.91%Forma y color:SolidPeso molecular:302.36Dioscin
CAS:<p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>Fórmula:C45H72O16Pureza:99.85% - 99.87%Forma y color:SolidPeso molecular:869.04Elubrixin HCl
CAS:<p>Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist.</p>Fórmula:C17H18Cl3FN4O4SForma y color:SolidPeso molecular:499.77Piperlongumine
CAS:<p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>Fórmula:C17H19NO5Pureza:97.03% - 99.90%Forma y color:SolidPeso molecular:317.34Oxyresveratrol
CAS:<p>1.</p>Fórmula:C14H12O4Pureza:98.09% - 99.69%Forma y color:Yellow SolidPeso molecular:244.24LC3-mHTT-IN-AN1
CAS:<p>LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B.</p>Fórmula:C15H9Br2NO3Pureza:97.26%Forma y color:SolidPeso molecular:411.04Tezacaftor
CAS:<p>Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.</p>Fórmula:C26H27F3N2O6Pureza:98.84% - >99.99%Forma y color:SolidPeso molecular:520.5AS-605240
CAS:<p>AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).</p>Fórmula:C12H7N3O2SPureza:97% - 99.91%Forma y color:SolidPeso molecular:257.273-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Fórmula:C3H3BrO3Pureza:95% - 99.644%Forma y color:White To Pale Yellow Crystalline PowderPeso molecular:166.96ML327
CAS:<p>ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).</p>Fórmula:C19H18N4O4Pureza:98.47%Forma y color:SolidPeso molecular:366.37Dorsomorphin
CAS:<p>Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.</p>Fórmula:C24H25N5OPureza:98% - 99.06%Forma y color:SolidPeso molecular:399.49Rac-Belinostat
CAS:<p>Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.</p>Fórmula:C15H14N2O4SPureza:99.67% - 99.96%Forma y color:SolidPeso molecular:318.35PHA-665752
CAS:<p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.</p>Fórmula:C32H34Cl2N4O4SPureza:97.05% - 98.82%Forma y color:SolidPeso molecular:641.61Alisertib
CAS:<p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.</p>Fórmula:C27H20ClFN4O4Pureza:98.31% - >99.99%Forma y color:SolidPeso molecular:518.92LYS01
CAS:<p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>Fórmula:C23H23Cl2N5Pureza:98.28%Forma y color:SolidPeso molecular:440.37Polydatin
CAS:<p>Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.</p>Fórmula:C20H22O8Pureza:97.2% - 98.94%Forma y color:White Fine PowderPeso molecular:390.38Juglanin
CAS:<p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>Fórmula:C20H18O10Pureza:98.8% - 99.33%Forma y color:SolidPeso molecular:418.35Tubastatin A
CAS:<p>Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.</p>Fórmula:C20H21N3O2Pureza:97.22% - 99.51%Forma y color:SolidPeso molecular:335.4Meglutol
CAS:<p>Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.</p>Fórmula:C6H10O5Pureza:99.73% - 99.94%Forma y color:SolidPeso molecular:162.14Retro-2
CAS:<p>Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.</p>Fórmula:C19H16N2OSPureza:98.15%Forma y color:SolidPeso molecular:320.41NVP-AEW541
CAS:<p>NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based</p>Fórmula:C27H29N5OPureza:98.7% - 99.86%Forma y color:SolidPeso molecular:439.55Lys05
CAS:<p>Lys05, a potent autophagy inhibitor, outperforms HCQ in cancer treatment, showing promise for drug development.</p>Fórmula:C23H26Cl5N5Pureza:99.13% - 99.55%Forma y color:SolidPeso molecular:549.75MK-2206 dihydrochloride
CAS:<p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>Fórmula:C25H23Cl2N5OPureza:99.228% - 99.94%Forma y color:SolidPeso molecular:480.39Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Fórmula:C19H18O9Pureza:99.64% - 99.85%Forma y color:SolidPeso molecular:390.34Fasudil dihydrochloride
CAS:<p>Fasudil dihydrochloride (HA-1077/AT877) is a RhoA/ROCK inhibitor with kinase-blocking properties and acts as a vasodilator.</p>Fórmula:C14H19Cl2N3O2SForma y color:SolidPeso molecular:364.29Diosgenin glucoside
CAS:<p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>Fórmula:C33H52O8Pureza:97.17% - 99.44%Forma y color:SolidPeso molecular:576.76PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Forma y color:SolidPeso molecular:237.32Quisinostat dihydrochloride
CAS:<p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>Fórmula:C21H28Cl2N6O2Pureza:97.13%Forma y color:SolidPeso molecular:467.39MRT68921 dihydrochloride
CAS:<p>MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).</p>Fórmula:C25H36Cl2N6OPureza:98.91% - 99.92%Forma y color:SolidPeso molecular:507.499FIPI HCl
CAS:<p>FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.</p>Fórmula:C23H25ClFN5O2Forma y color:SolidPeso molecular:457.93Schisandrol B
CAS:<p>Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.</p>Fórmula:C23H28O7Pureza:99.14% - 99.95%Forma y color:SolidPeso molecular:416.46Lapatinib tosylate
CAS:<p>Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).</p>Fórmula:C36H34ClFN4O7S2Forma y color:SolidPeso molecular:753.26Brefeldin A
CAS:<p>Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).</p>Fórmula:C16H24O4Pureza:96.45% - 99.89%Forma y color:White SolidPeso molecular:280.36Sanguinarine
CAS:<p>Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.</p>Fórmula:C20H14NO4Pureza:99.04% - 99.76%Forma y color:SolidPeso molecular:332.33Idarubicin
CAS:<p>Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.</p>Fórmula:C26H27NO9Forma y color:SolidPeso molecular:497.49FIPI
CAS:<p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>Fórmula:C23H24FN5O2Pureza:97.21% - 98.68%Forma y color:SolidPeso molecular:421.47MRT68921 HCl
CAS:<p>MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).</p>Fórmula:C25H34N6O·HClPureza:99.86% - 99.98%Forma y color:SolidPeso molecular:471.04ABT-737
CAS:<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Fórmula:C42H45ClN6O5S2Pureza:98.15% - >99.99%Forma y color:SolidPeso molecular:813.43Dinoprost tromethamine salt
CAS:<p>Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.</p>Fórmula:C24H45NO8Pureza:99.73%Forma y color:Natural Form Crystals SolidPeso molecular:475.62Calcimycin
CAS:<p>Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.</p>Fórmula:C29H37N3O6Pureza:98%Forma y color:SolidPeso molecular:523.62Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Fórmula:C15H22N2OPureza:99.89%Forma y color:SolidPeso molecular:246.35Fasudil hydrochloride hydrate
CAS:<p>Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.</p>Fórmula:C28H38Cl2N6O5S2Forma y color:SolidPeso molecular:673.67Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Forma y color:SolidPeso molecular:532.61Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Fórmula:C51H82O21Pureza:99.51% - 99.63%Forma y color:SolidPeso molecular:1031.18Quercitrin
CAS:<p>Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.</p>Fórmula:C21H20O11Pureza:98.89% - 99.66%Forma y color:Yellow Crystals From Dil Methanol Or Ethanol SolidPeso molecular:448.38Everolimus
CAS:<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Fórmula:C53H83NO14Pureza:97.76% - 99.78%Forma y color:Off-White To Light Yellow PowdPeso molecular:958.22Vandetanib
CAS:<p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>Fórmula:C22H24BrFN4O2Pureza:99.7% - >99.99%Forma y color:White SolidPeso molecular:475.35Nutlin-3a
CAS:<p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C30H30Cl2N4O4Pureza:95.62% - 99.71%Forma y color:SolidPeso molecular:581.49PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Forma y color:SolidPeso molecular:369.22Schisandrin
CAS:<p>Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.</p>Fórmula:C24H32O7Pureza:98.97% - 99.32%Forma y color:White PowderPeso molecular:432.51NS1643
CAS:<p>NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.</p>Fórmula:C15H10F6N2O3Pureza:98.37% - 99.31%Forma y color:SolidPeso molecular:380.24GLPG1837
CAS:<p>GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.</p>Fórmula:C16H20N4O3SPureza:99.64% - 99.91%Forma y color:SolidPeso molecular:348.42DPN
CAS:<p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>Fórmula:C15H13NO2Pureza:99.01%Forma y color:Off-White SolidPeso molecular:239.27Tacrolimus monohydrate
CAS:<p>Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.</p>Fórmula:C44H71NO13Pureza:97.07% - 98.05%Forma y color:SolidPeso molecular:822.05UBCS039
CAS:<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Fórmula:C16H13N3Pureza:98.31%Forma y color:SolidPeso molecular:247.29Capivasertib
CAS:<p>Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.</p>Fórmula:C21H25ClN6O2Pureza:97.59% - 99.6%Forma y color:SolidPeso molecular:428.92Carbamazepine
CAS:<p>Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.</p>Fórmula:C15H12N2OPureza:99.78% - 99.79%Forma y color:SolidPeso molecular:236.27
