Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1424 productos de "Autofagia"
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CXCR4 antagonist 1
CAS:<p>CXCR4 antagonist 1 is a potent inhibitor of the CXCR4 receptor, with notable anti-HIV activity.</p>Fórmula:C27H43N7Forma y color:SolidPeso molecular:465.69(3R,5S)-Fluvastatin
CAS:<p>(3R,5S)-Fluvastatin, a synthetic HMG-CoA reductase inhibitor (IC50: 8 nM), activates Nrf2 for antioxidant defense.</p>Fórmula:C24H26FNO4Forma y color:SolidPeso molecular:411.47MW-150 hydrochloride
CAS:<p>MW-150 hydrochloride is a selective p38α MAPK inhibitor with a 101 nM Ki, offering good CNS penetration and oral bioavailability.</p>Fórmula:C24H24ClN5Forma y color:SolidPeso molecular:417.93Bacilotetrin C analogue
<p>Bacilotetrin C analogue is a variant of Bacilotetrin C. It exhibits cytotoxicity against the triple-negative breast cancer cell line MDA-MB-231, with an IC50 of 0.48 μM. This compound induces autophagy (autophagy) in tumor cells and possesses antitumor activity.</p>Fórmula:C44H76N6O10Forma y color:SolidPeso molecular:849.11MeCY5-NHS ester triethylamine
<p>MeCY5-NHS ester (potassium) is a reactive dye optimized for labeling proteins and nucleic acids [1].</p>Fórmula:C42H56N4O10S2Forma y color:SolidPeso molecular:841.04p62-ZZ Ligand-Linker Conjugate 1
CAS:<p>p62-ZZ Ligand-Linker Conjugate 1 is a conjugate of the p62-ZZ domain ligand and linker. This compound is utilized in the synthesis of AUTOTACVinclozolinM2-2204.</p>Fórmula:C31H42N2O6Forma y color:SolidPeso molecular:538.68Syntide 2
CAS:<p>Syntide-2 is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 µM).</p>Fórmula:C68H122N20O18Pureza:98%Forma y color:Lyophilized SolidPeso molecular:1507.82Cyanine 5 Tyramide methyl indole
<p>Cyanine 5 Tyramide is a red dye used in HRP assays and nucleic acid hybridization. Store away from light.</p>Fórmula:C40H47N3O8S2Forma y color:SolidPeso molecular:761.95Chlorotris(triphenylphosphine)copper
CAS:<p>Chlorotris (triphenylphosphine) copper (CuCl(TPP)₃) is a metal complex that targets DNA. Through non-covalent interactions of its copper (I) center, such as groove-binding, it affects DNA function and exhibits inhibitory activity against bacteria, fungi, and tumor cells. Chlorotris (triphenylphosphine) copper holds potential for research as an antimicrobial, antitumor, and antioxidant agent.</p>Fórmula:C54H45ClCuP3Forma y color:SolidPeso molecular:885.86Fasudil
CAS:<p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>Fórmula:C14H17N3O2SPureza:99.79% - 99.84%Forma y color:SolidPeso molecular:291.37Hexidium iodide
CAS:<p>Hexidium iodide fluoresces, stains mammalian cells & gram-positive bacteria, and binds to DNA with EDTA. Excitation/emission: ~518/600 nm.</p>Fórmula:C25H28IN3Forma y color:SolidPeso molecular:497.424ALX 40-4C
CAS:<p>ALX40-4C is a small peptide inhibitor of the chemokine receptor CXCR4 that can inhibit X4 strains of HIV-1.</p>Fórmula:C56H113N37O10Pureza:98%Forma y color:SolidPeso molecular:1464.74PROTAC EGFR degrader 4
CAS:<p>PROTAC EGFR degrader 4 targets mutant EGFR, degrades del19 and L858R/T790M (DC50: 0.51, 126 nM), and inhibits HCC827, H1975 cell growth (IC50: 0.83, 203.1 nM).</p>Fórmula:C55H70N12O4SForma y color:SolidPeso molecular:995.29Tricyclic cytosine tC
CAS:<p>Tricyclic cytosine (tC) is a fluorescent analog of cytosine designed for RNA imaging within live cells, facilitating the study of RNA synthesis, degradation,</p>Fórmula:C15H15N3O5SForma y color:SolidPeso molecular:349.36JH-XII-03-02
CAS:<p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>Fórmula:C43H51N9O10Pureza:98%Forma y color:SolidPeso molecular:853.92Desfluoro-ezetimibe
CAS:<p>Desfluoro-ezetimibe: a defluorinated ezetimibe impurity; a stable, potent cholesterol blocker and Nrf2 activator.</p>Fórmula:C24H22FNO3Pureza:98%Forma y color:SolidPeso molecular:391.43Acetyl coenzyme A
CAS:<p>Acetyl coenzyme A (Acetyl-CoA) is a pivotal molecule connecting multiple cellular metabolic pathways in the tricarboxylic acid cycle, fatty acid synthesis</p>Fórmula:C23H38N7O17P3SForma y color:SolidPeso molecular:809.57PI3K-AKT-mTOR Compound Library
<p>A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with</p>Forma y color:Odour SolidCTCE-9908
CAS:<p>CXCR4 blocker; triggers cell division failure in ovarian cancer, boosts taxol and docetaxel treatment effects, proven in mice.</p>Fórmula:C86H147N27O23Pureza:98%Forma y color:SolidPeso molecular:1927.27CXCR4 antagonist 2
CAS:<p>CXCR4 antagonist 2 is a CXCR4 antagonist with an IC 50 value of 47 nM.</p>Fórmula:C25H36N6Forma y color:SolidPeso molecular:420.605
