Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1424 productos de "Autofagia"
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CXCR2 antagonist 8
CAS:<p>CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.</p>Fórmula:C14H13N3O5Forma y color:SolidPeso molecular:303.27Tetrahydrocurcumin D6
CAS:<p>Tetrahydrocurcumin D6 is a deuterium labeled Tetrahydrocurcumin. Tetrahydrocurcumin displays inhibitory activity for CYP2C9 and CYP3A4.</p>Fórmula:C21H24O6Pureza:98%Forma y color:SolidPeso molecular:378.45TRAF6 peptide TFA
<p>TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA.</p>Fórmula:C145H238N34O44·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:3161.64 (free acid)Manzamine A
CAS:<p>Manzamine A, from marine sponges, blocks GSK-3, halts cancer growth, prevents bacterial infections, and reduces tau phosphorylation.</p>Fórmula:C36H44N4OPureza:98%Forma y color:SolidPeso molecular:548.775PS372424 hydrochloride
CAS:<p>PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.</p>Fórmula:C33H45ClN6O4Pureza:95.03%Forma y color:SolidPeso molecular:625.2Erlotinib-d6 hydrochloride
CAS:<p>Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.</p>Fórmula:C22H24ClN3O4Pureza:98%Forma y color:SolidPeso molecular:435.93Idelalisib D5
CAS:<p>Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ.</p>Fórmula:C22H18FN7OPureza:98%Forma y color:SolidPeso molecular:420.45Ladarixin
CAS:<p>Ladarixin (DF 2156A free base) is an orally active, non-competitive CXCR1/CXCR2 allosteric inhibitor that suppresses AKT, NF-κB, and angiogenesis.</p>Fórmula:C11H12F3NO6S2Pureza:99.36%Forma y color:SolidPeso molecular:375.34Silibinin-d3
<p>Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.</p>Fórmula:C25H22O10Forma y color:SolidPeso molecular:485.46Curcumin-d6
CAS:<p>Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-a</p>Fórmula:C21H20O6Pureza:98%Forma y color:SolidPeso molecular:374.422Isoniazid-d4
CAS:<p>Isoniazid-d4 is a deuterium isotope marker for Isoniazid.Isoniazid is a prodrug that must be activated by the bacterial peroxidase KatG, and is bactericidal.</p>Fórmula:C6H3D4N3OForma y color:SolidPeso molecular:141.16Binimetinib-13C-d3
<p>Binimetinib-13C-d3 (MEK162) is an isotopically labelled compound of Binimetinib.Binimetinib (ARRY-162) is a selective MEK1/2 inhibitor melanoma.</p>Fórmula:C17H15BrF2N4O3Forma y color:SolidPeso molecular:445.24Regorafenib-d3
CAS:<p>Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.</p>Fórmula:C21H15ClF4N4O3Pureza:98%Forma y color:SolidPeso molecular:485.83Loperamide-d6 hydrochloride
CAS:<p>Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.</p>Fórmula:C29H34Cl2N2O2Pureza:98%Forma y color:SolidPeso molecular:519.54THZ-P1-2
CAS:<p>THZ-P1-2 is a PI5P4K inhibitor with anti-leukemic activity and can be used in the study of leukemia.</p>Fórmula:C31H29N7O2Forma y color:SolidPeso molecular:531.61Peptide R TFA
<p>Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.</p>Fórmula:C39H57N13O8S2·xC2HF3O2Forma y color:SolidPeso molecular:900.08 (free base)Br-DAPI
CAS:<p>IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.</p>Fórmula:C16H14BrN5Pureza:100%Forma y color:SolidPeso molecular:356.22Imatinib D4
CAS:<p>Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.</p>Fórmula:C29H31N7OPureza:98%Forma y color:SolidPeso molecular:497.63OR-1855
CAS:<p>OR-1855 is an active Levosimendan metabolite, has effect on human myometrial contractility.</p>Fórmula:C11H13N3OPureza:98%Forma y color:Pale Yellow SolidPeso molecular:203.24Brivanib
CAS:<p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against</p>Fórmula:C19H19FN4O3Pureza:98.87%Forma y color:SolidPeso molecular:370.38
