Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1424 productos de "Autofagia"
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Metformin-d6 hydrochloride
CAS:<p>Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.</p>Fórmula:C4H12ClN5Pureza:98.1%Forma y color:SolidPeso molecular:171.66OR-1855
CAS:<p>OR-1855 is an active Levosimendan metabolite, has effect on human myometrial contractility.</p>Fórmula:C11H13N3OPureza:98%Forma y color:Pale Yellow SolidPeso molecular:203.24Peptide R TFA
<p>Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.</p>Fórmula:C39H57N13O8S2·xC2HF3O2Forma y color:SolidPeso molecular:900.08 (free base)Gefitinib-d8
CAS:<p>Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.</p>Fórmula:C22H24ClFN4O3Pureza:98%Forma y color:SolidPeso molecular:454.95LY2510924
CAS:<p>LY2510924 is an effective and selective CXCR4 antagonist. It blocks SDF-1 binding to CXCR4 (IC50: 0.079 nM).</p>Fórmula:C62H88N14O10Forma y color:SolidPeso molecular:1189.45Pemetrexed disodium heptahydrate
CAS:<p>Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits TS, DHFR and GARFT, inhibits precursor purine and pyrimidine nucleotides.</p>Fórmula:C20H33N5Na2O13Pureza:99.783%Forma y color:SolidPeso molecular:597.49Brivanib
CAS:<p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against</p>Fórmula:C19H19FN4O3Pureza:98.87%Forma y color:SolidPeso molecular:370.38IKK 16 hydrochloride
CAS:<p>IKK 16 hydrochloride, a potent IKK1/2 and LRRK2 inhibitor, IC50s: 40-200 nM and 50 nM respectively.</p>Fórmula:C28H30ClN5OSForma y color:SolidPeso molecular:520.09Regorafenib-d3
CAS:<p>Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.</p>Fórmula:C21H15ClF4N4O3Pureza:98%Forma y color:SolidPeso molecular:485.83Cediranib maleate
CAS:<p>Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.</p>Fórmula:C29H31FN4O7Forma y color:SolidPeso molecular:566.58Resveratrol analog 1
CAS:<p>Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.</p>Fórmula:C14H11FO2Pureza:98.42%Forma y color:SolidPeso molecular:230.23Rupatadine
CAS:<p>Rupatadine (UR-12592, rupatadine) is a potent and orally available dual antagonist of PAF and histamine H1 receptors ,allergic and anti-inflammatory.</p>Fórmula:C26H26ClN3Pureza:99.87%Forma y color:SolidPeso molecular:415.96Dexamethasone-d5
CAS:<p>Dexamethasone-d5 is a deuterated compound of Dexamethasone.</p>Fórmula:C22H24D5FO5Forma y color:SolidPeso molecular:397.49Silibinin-d3
<p>Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.</p>Fórmula:C25H22O10Forma y color:SolidPeso molecular:485.46Pyrazinamide-d3
CAS:<p>Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.</p>Fórmula:C5D3H2N3OForma y color:SolidPeso molecular:126.13Binimetinib-13C-d3
<p>Binimetinib-13C-d3 (MEK162) is an isotopically labelled compound of Binimetinib.Binimetinib (ARRY-162) is a selective MEK1/2 inhibitor melanoma.</p>Fórmula:C17H15BrF2N4O3Forma y color:SolidPeso molecular:445.24V-9302 hydrochloride
CAS:<p>V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5.</p>Fórmula:C34H39ClN2O4Pureza:97.31%Forma y color:SolidPeso molecular:575.14Loperamide-d6 hydrochloride
CAS:<p>Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.</p>Fórmula:C29H34Cl2N2O2Pureza:98%Forma y color:SolidPeso molecular:519.54Afatinib D6
CAS:<p>Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.</p>Fórmula:C24H25ClFN5O3Forma y color:SolidPeso molecular:491.98Trimetazidine
CAS:<p>Trimetazidine is a antianginal agent that selectively inhibits the mitochondrial enzyme LC 3-KAT, thereby preventing β-oxidation of free fatty acids.</p>Fórmula:C14H22N2O3Pureza:99.9%Forma y color:Hite Or Off-White Crystalline PowderPeso molecular:266.34
