Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1424 productos de "Autofagia"
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Schisandrol B
CAS:<p>Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.</p>Fórmula:C23H28O7Pureza:99.14% - 99.95%Forma y color:SolidPeso molecular:416.46Eupatilin
CAS:<p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>Fórmula:C18H16O7Pureza:98.53% - 99%Forma y color:SolidPeso molecular:344.32Lapatinib tosylate
CAS:<p>Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).</p>Fórmula:C36H34ClFN4O7S2Forma y color:SolidPeso molecular:753.26Brefeldin A
CAS:<p>Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).</p>Fórmula:C16H24O4Pureza:96.45% - 99.89%Forma y color:White SolidPeso molecular:280.36Sanguinarine
CAS:<p>Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.</p>Fórmula:C20H14NO4Pureza:99.04% - 99.76%Forma y color:SolidPeso molecular:332.33LYN-1604
CAS:<p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>Fórmula:C33H43Cl2N3O2Pureza:98%Forma y color:SolidPeso molecular:584.62Idarubicin
CAS:<p>Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.</p>Fórmula:C26H27NO9Forma y color:SolidPeso molecular:497.49Tropifexor
CAS:<p>Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.</p>Fórmula:C29H25F4N3O5SPureza:99.3% - 99.85%Forma y color:SolidPeso molecular:603.58MRT68921 HCl
CAS:<p>MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).</p>Fórmula:C25H34N6O·HClPureza:99.86% - 99.98%Forma y color:SolidPeso molecular:471.04ABT-737
CAS:<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Fórmula:C42H45ClN6O5S2Pureza:98.15% - >99.99%Forma y color:SolidPeso molecular:813.43Dinoprost tromethamine salt
CAS:<p>Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.</p>Fórmula:C24H45NO8Pureza:99.73%Forma y color:Natural Form Crystals SolidPeso molecular:475.62Dorsomorphin
CAS:<p>Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.</p>Fórmula:C24H25N5OPureza:98% - 99.06%Forma y color:SolidPeso molecular:399.49Calcimycin
CAS:<p>Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.</p>Fórmula:C29H37N3O6Pureza:98%Forma y color:SolidPeso molecular:523.62Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Fórmula:C15H22N2OPureza:99.89%Forma y color:SolidPeso molecular:246.35Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Forma y color:SolidPeso molecular:532.61FIPI HCl
CAS:<p>FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.</p>Fórmula:C23H25ClFN5O2Forma y color:SolidPeso molecular:457.93URB-597
CAS:<p>URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.</p>Fórmula:C20H22N2O3Pureza:97.20% - 98.24%Forma y color:SolidPeso molecular:338.4TG101209
CAS:<p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>Fórmula:C26H35N7O2SPureza:99% - >99.99%Forma y color:SolidPeso molecular:509.67Cucurbitacin E
CAS:<p>Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.</p>Fórmula:C32H44O8Pureza:98.88% - 99.87%Forma y color:SolidPeso molecular:556.69Everolimus
CAS:<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Fórmula:C53H83NO14Pureza:97.76% - 99.78%Forma y color:Off-White To Light Yellow PowdPeso molecular:958.22
