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Receptor de endotelina

Receptor de endotelina

Los receptores de endotelina son GPCR que median los efectos de las endotelinas, péptidos vasoconstrictores potentes que desempeñan un papel significativo en la regulación del tono vascular, el control de la presión arterial y la proliferación celular. Los antagonistas de los receptores de endotelina se utilizan en el tratamiento de afecciones como la hipertensión arterial pulmonar y la insuficiencia cardíaca. Estos receptores también son objetivos importantes en la investigación sobre enfermedades cardiovasculares y cáncer. En CymitQuimica, ofrecemos una selección de moduladores de receptores de endotelina de alta calidad para apoyar su investigación en biología cardiovascular, oncología y fisiología vascular.

Se han encontrado 86 productos de "Receptor de endotelina"

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  • Sulfisoxazole

    CAS:
    Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.
    Fórmula:C11H13N3O3S
    Pureza:99.87% - 99.98%
    Forma y color:White To Cream Powder
    Peso molecular:267.30

    Ref: TM-T0750

    1g
    71,00€
    200mg
    34,00€
    500mg
    50,00€
    1mL*10mM (DMSO)
    33,00€
  • Enrasentan

    CAS:
    Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure and protects myocardial function.
    Fórmula:C29H30O8
    Pureza:97.9% - 98.39%
    Forma y color:Solid
    Peso molecular:506.54

    Ref: TM-T31640

    1mg
    185,00€
    5mg
    459,00€
    10mg
    657,00€
    25mg
    1.031,00€
  • Atrial Natriuretic Peptide (ANP) (1-28), rat

    CAS:
    Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
    Fórmula:C128H205N45O39S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3062.41

    Ref: TM-TP1221

    1mg
    1.378,00€
  • Atrial natriuretic factor (1-28) (rat) TFA


    ANP (1-28), rat (TFA) inhibits Ang II-induced endothelin-1 secretion; main circulating ANP form in rats.
    Fórmula:C130H206N45F3O41S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3176.43

    Ref: TM-TP1218

    1mg
    217,00€
    5mg
    770,00€
  • ACT-373898

    CAS:

    ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ETA) and ETBdual antagonist macitentan .1

    Fórmula:C15H17BrN4O5S
    Forma y color:Solid
    Peso molecular:445.29

    Ref: TM-T35623

    1mg
    92,00€
    5mg
    275,00€
    10mg
    464,00€
    25mg
    944,00€
  • IRL-1038

    CAS:
    ETB endothelin receptor antagonist
    Fórmula:C68H92N14O15S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1409.67

    Ref: TM-TP2262

    1mg
    A consultar
    100mg
    A consultar
    500mg
    A consultar
  • [Ala1,3,11,15]-Endothelin

    CAS:
    Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
    Fórmula:C109H163N25O32S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2368

    Ref: TM-TP2099

    5mg
    477,00€
  • Nebentan

    CAS:

    Nebentan (YM598) is an oral, selective ETA antagonist; Ki: 0.697 nM (ETA), 569 nM (ETB); may slow cor pulmonale, myocardial infarction.

    Fórmula:C24H21N5O5S
    Forma y color:Solid
    Peso molecular:491.52

    Ref: TM-T36007

    5mg
    187,00€
    10mg
    315,00€
    25mg
    552,00€
  • SB234551

    CAS:
    SB234551 is a selective antagonist of endothelin ETA receptor.
    Fórmula:C34H34N2O9
    Forma y color:Solid
    Peso molecular:614.64

    Ref: TM-T28683

    25mg
    A consultar
    50mg
    A consultar
    100mg
    A consultar
  • IRL-3630

    CAS:
    IRL 3460 is an enantiomer.
    Fórmula:C31H40N4O6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:596.74

    Ref: TM-T25541

    25mg
    A consultar
    50mg
    A consultar
    100mg
    A consultar
  • Sarafotoxin S6b

    CAS:
    non-selective endothelin receptor agonist
    Fórmula:C110H163N27O34S5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2567.96

    Ref: TM-TP2290

    1mg
    A consultar
    100mg
    A consultar
    500mg
    A consultar
  • Sarafotoxin S6c

    CAS:
    Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).
    Fórmula:C103H147N27O37S5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2516

    Ref: TM-TP2120

    100µg
    888,00€
  • PD 142893

    CAS:
    PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.
    Fórmula:C50H65N7O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:924.09

    Ref: TM-T25922

    25mg
    1.369,00€
  • IRL-1620

    CAS:
    IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).
    Fórmula:C86H117N17O27
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1820.974

    Ref: TM-T15595

    500µg
    909,00€
  • Sarafotoxin S6a

    CAS:
    Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.
    Fórmula:C105H156N28O34S5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2514.85

    Ref: TM-TP2119

    1mg
    485,00€
  • BQ-123 TFA


    BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.
    Fórmula:C33H43F3N6O9
    Forma y color:Solid
    Peso molecular:724.72

    Ref: TM-T73877

    5mg
    A consultar
    50mg
    A consultar
  • [Ala2] Endothelin-3, human

    CAS:
    [Ala2] Endothelin-3, a linear ET-3 analog with Ala replacing Cys, stimulates endothelial cell migration.
    Fórmula:C120H166N26O32S4
    Forma y color:Solid
    Peso molecular:2613.02

    Ref: TM-T76305

    5mg
    A consultar
    50mg
    A consultar
  • Endothelin 1 (swine, human), Alexa Fluor 488-labeled


    Synthetic human/swine Endothelin 1 peptide, tagged with Alexa Fluor 488, acts as a strong vasoconstrictor via ET A/B receptors.
    Forma y color:Solid
    Peso molecular:2848.4

    Ref: TM-T76081

    5mg
    A consultar
    50mg
    A consultar
  • [Lys4] Sarafotoxin S6c

    CAS:
    [Lys4] Sarafotoxin S6c: potent partial endothelin receptor agonist; causes pig coronary contraction, EC50=1.5 nM.
    Fórmula:C105H153N27O36S5
    Forma y color:Solid
    Peso molecular:2529.82

    Ref: TM-T76302

    5mg
    A consultar
    50mg
    A consultar
  • Endothelin-2 (49-69), human TFA


    Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.
    Fórmula:C117H161N26F3O34S4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2660.94

    Ref: TM-TP2143

    100mg
    A consultar
    500mg
    A consultar
  • Methylsolfonyl 25(S)-Δ7-dafachronic acid


    Methylsulfonyl 25(S)-Δ7-dafachronic acid (compound 3) is a selective ssDAF-12 agonist with an IC50 value of 0.41 μM. It exhibits low cytotoxicity in HepG2 cells, with an IC50 value greater than 200 μM. Methylsulfonyl 25(S)-Δ7-dafachronic acid is applicable in the study of parasitic diseases.
    Fórmula:C28H45NO4S
    Peso molecular:491.30693

    Ref: TM-T209317

    10mg
    A consultar
    50mg
    A consultar
  • Endothelin 1 (swine, human) (TFA)

    CAS:
    Synthetic human/swine Endothelin 1 (TFA) peptide; a potent vasoconstrictor acting on ET A and ET B receptors.
    Fórmula:C111H160F3N25O34S5
    Peso molecular:2605.93

    Ref: TM-T75731

    5mg
    A consultar
    50mg
    A consultar
  • Bosentan-d4

    CAS:
    Bosentan-d4: deuterium version of Bosentan, competitive ET A/B antagonist, Ki: 4.7nM (ET A), 95nM (ET B) in human SMC.
    Fórmula:C27H25D4N5O6S
    Forma y color:Solid
    Peso molecular:555.64

    Ref: TM-T73820

    5mg
    898,00€
  • ANP (1-30), frog

    CAS:
    ANP (1-30), frog, a peptide fragment sourced from atrial natriuretic peptide of frog origin, exhibits natriuretic, diuretic, and vasorelaxant properties.
    Fórmula:C131H217N49O41S4
    Forma y color:Solid
    Peso molecular:3262.69

    Ref: TM-T76386

    5mg
    A consultar
    50mg
    A consultar
  • Big endothelin-1 (rat 1-39)

    CAS:
    Big endothelin-1 (rat 1-39), a 39-residue peptide, induces a diuretic and natriuretic response in conscious Sprague-Dawley rats and elevates blood pressure in
    Forma y color:Solid

    Ref: TM-T82886

    5mg
    A consultar
    50mg
    A consultar
  • [Asn18] Endothelin-1, human

    CAS:
    [Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1].
    Fórmula:C109H164N26O31S5
    Peso molecular:2494.96

    Ref: TM-T76329

    5mg
    A consultar
    50mg
    A consultar
  • Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

    CAS:
    Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate is an NPR-A agonist and ANP hormone. Carperitide increases cGMP levels and reduces the heart's workload.
    Fórmula:C129H207N45O41S3
    Pureza:99.78%
    Forma y color:Soild
    Peso molecular:3140.5

    Ref: TM-TP1219

    1mg
    175,00€
    5mg
    434,00€
    10mg
    622,00€
    25mg
    973,00€
    50mg
    1.314,00€
    100mg
    1.773,00€
    200mg
    2.395,00€
  • IRL-1038 acetate


    IRL-1038 acetate is a potent ETB endothelin receptor antagonist.
    Fórmula:C70H96N14O17S2
    Pureza:97.51%
    Forma y color:Soild
    Peso molecular:1469.73

    Ref: TM-TP2262L

    1mg
    409,00€
    5mg
    947,00€
    10mg
    1.415,00€
    25mg
    2.422,00€
    50mg
    3.258,00€
  • IRL-1038 TFA


    IRL-1038 TFA is an ETB receptor antagonist used in the study of cardiovascular disease.
    Fórmula:C70H93F3N14O17S2
    Pureza:98.79%
    Forma y color:Solid
    Peso molecular:1523.7

    Ref: TM-TP2262L1

    1mg
    38,00€
    5mg
    59,00€
    10mg
    83,00€
  • IRL-1620 acetate


    IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.
    Fórmula:C88H121N17O29
    Pureza:96.64%
    Forma y color:Solid
    Peso molecular:1881

    Ref: TM-T15595L

    1mg
    180,00€
    5mg
    445,00€
    10mg
    652,00€
    25mg
    1.026,00€
    50mg
    1.378,00€
    100mg
    1.863,00€
  • Atrial natriuretic peptide (3-28) (human)

    CAS:
    Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation of
    Fórmula:C118H187N43O36S3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2880.21

    Ref: TM-T80438

    5mg
    A consultar
    50mg
    A consultar
  • Sulfatroxazole

    CAS:
    Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of the ETA receptor with an IC50 of 0.26 μM.
    Fórmula:C11H13N3O3S
    Forma y color:Solid
    Peso molecular:267.3

    Ref: TM-T203689

    10mg
    A consultar
    50mg
    A consultar
  • BQ-3020 ammonium


    BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2
    Fórmula:C96H140N20O25S·xNH3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2006.32 (free base)

    Ref: TM-T78096

    5mg
    A consultar
    50mg
    A consultar
  • Endothelin-3 (Rat,Human) (TFA)


    Endothelin-3 (Rat, Human) (TFA) is a 21-amino acid vasoactive peptide of endothelial origi, an agonist for the endothelin receptor type B (EDNRB).
    Fórmula:C123H169F3N26O35S4·xC2HF3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2757.07 (free base)

    Ref: TM-TP1173

    1mg
    567,00€
  • Sitaxsentan sodium

    CAS:
    Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.
    Fórmula:C18H14ClN2O6S2·Na
    Pureza:98.39% - 99.01%
    Forma y color:Solid
    Peso molecular:476.89

    Ref: TM-T6672

    5mg
    35,00€
    10mg
    58,00€
    25mg
    101,00€
    50mg
    170,00€
    100mg
    273,00€
    200mg
    398,00€
    1mL*10mM (DMSO)
    38,00€
  • Bosentan

    CAS:
    Bosentan is a competitive endothelin receptor antagonist, used for treating pulmonary arterial hypertension.
    Fórmula:C27H29N5O6S
    Pureza:99.74% - 99.84%
    Forma y color:Pale Yellow To Off-White Solid
    Peso molecular:551.614

    Ref: TM-T6264

    10mg
    38,00€
    25mg
    56,00€
    50mg
    81,00€
    100mg
    127,00€
    200mg
    207,00€
    500mg
    310,00€
    1mL*10mM (DMSO)
    88,00€
  • Darusentan

    CAS:
    Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteries
    Fórmula:C22H22N2O6
    Pureza:98.72%
    Forma y color:Solid
    Peso molecular:410.43

    Ref: TM-T5458

    2mg
    46,00€
    5mg
    69,00€
    10mg
    105,00€
    25mg
    183,00€
    50mg
    304,00€
    100mg
    437,00€
    200mg
    615,00€
    1mL*10mM (DMSO)
    71,00€
  • BQ-123

    CAS:
    BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
    Fórmula:C31H42N6O7
    Pureza:99.22% - ≥95%
    Forma y color:Solid
    Peso molecular:610.7

    Ref: TM-T6792

    1mg
    88,00€
    5mg
    202,00€
    10mg
    329,00€
    25mg
    548,00€
    50mg
    782,00€
    100mg
    1.035,00€
    1mL*10mM (DMSO)
    274,00€
  • Ambrisentan sodium

    CAS:
    Ambrosentan (BSF 208075) sodium is a selective and oral effective antagonist of ET type A receptor ( ETAR ).
    Fórmula:C22H21N2NaO4
    Forma y color:Solid
    Peso molecular:400.41

    Ref: TM-T61921

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • BQ-788 sodium salt

    CAS:
    BQ-788 sodium salt is a potent and selective antagonist of ETB receptor(ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells).
    Fórmula:C34H51N5NaO7
    Forma y color:Solid
    Peso molecular:664.8

    Ref: TM-T10595L

    2mg
    256,00€
    25mg
    879,00€
    50mg
    1.144,00€
    100mg
    1.738,00€
  • Atrasentan sodium

    CAS:
    Atrasentan (ABT-627) is an oral ETA receptor blocker with potential cancer-fighting properties, inhibiting angiogenesis and tumor growth.
    Fórmula:C29H37N2NaO6
    Forma y color:Solid
    Peso molecular:532.61

    Ref: TM-T70198

    25mg
    1.586,00€
    50mg
    2.072,00€
    100mg
    2.660,00€
  • Ro 46-2005

    CAS:
    Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 nM).
    Fórmula:C23H27N3O6S
    Pureza:98.02% - 98.8%
    Forma y color:Solid
    Peso molecular:473.54

    Ref: TM-T3194

    5mg
    43,00€
    10mg
    75,00€
    25mg
    124,00€
    50mg
    200,00€
    100mg
    288,00€
    200mg
    414,00€
    1mL*10mM (DMSO)
    47,00€
  • RO 46-8443

    CAS:
    RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.
    Fórmula:C31H35N3O8S
    Pureza:98.77% - 99.77%
    Forma y color:Solid
    Peso molecular:609.69

    Ref: TM-T3474

    1mg
    38,00€
    2mg
    50,00€
    5mg
    84,00€
    10mg
    119,00€
    25mg
    236,00€
    50mg
    334,00€
    100mg
    495,00€
    500mg
    1.054,00€
  • Bosentan (hydrate)

    CAS:
    Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
    Fórmula:C27H29N5O6S·H2O
    Pureza:99.31% - 99.86%
    Forma y color:White Powder
    Peso molecular:569.63

    Ref: TM-T6265

    25mg
    47,00€
    50mg
    60,00€
    100mg
    96,00€
    1mL*10mM (DMSO)
    64,00€
  • Ambrisentan

    CAS:
    Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not linked to acute liver injury.
    Fórmula:C22H22N2O4
    Pureza:99.65% - 99.86%
    Forma y color:Solid
    Peso molecular:378.42

    Ref: TM-T1655

    5mg
    35,00€
    10mg
    46,00€
    25mg
    77,00€
    50mg
    105,00€
    100mg
    157,00€
    200mg
    224,00€
    1mL*10mM (DMSO)
    42,00€
  • Atrasentan

    CAS:
    Atrasentan (ABT-627) is an endothelin receptor antagonist that can inhibit the activity of ETA.Cost-effective and quality-assured.
    Fórmula:C29H38N2O6
    Pureza:97.65% - 99.08%
    Forma y color:Solid
    Peso molecular:510.62

    Ref: TM-TQ0259

    1mg
    46,00€
    5mg
    90,00€
    10mg
    130,00€
    25mg
    250,00€
    50mg
    356,00€
    100mg
    580,00€
    200mg
    798,00€
    1mL*10mM (DMSO)
    109,00€
  • Aprocitentan

    CAS:
    Aprocitentan (ACT-132577) is ETA and ETB antagonist .
    Fórmula:C16H14Br2N6O4S
    Pureza:99.17%
    Forma y color:Solid
    Peso molecular:546.19

    Ref: TM-T7817

    1mg
    58,00€
    5mg
    116,00€
    10mg
    170,00€
    25mg
    311,00€
    50mg
    439,00€
    100mg
    655,00€
    200mg
    887,00€
    1mL*10mM (DMSO)
    142,00€
  • Sparsentan

    CAS:
    Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM,
    Fórmula:C32H40N4O5S
    Pureza:97.94% - 98.69%
    Forma y color:Solid
    Peso molecular:592.75

    Ref: TM-T5355

    2mg
    39,00€
    5mg
    58,00€
    10mg
    94,00€
    25mg
    170,00€
    50mg
    259,00€
    100mg
    380,00€
    200mg
    540,00€
    1mL*10mM (DMSO)
    77,00€
  • BMS 182874 hydrochloride

    CAS:
    BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.
    Fórmula:C17H20ClN3O3S
    Pureza:97.01%
    Forma y color:Solid
    Peso molecular:381.88

    Ref: TM-T21790

    1mg
    77,00€
    2mg
    92,00€
    5mg
    140,00€
    10mg
    205,00€
    25mg
    343,00€
    50mg
    477,00€
    100mg
    665,00€
    200mg
    897,00€
    1mL*10mM (DMSO)
    146,00€
  • ANP(1-28) Acetate (human, porcine)

    CAS:
    Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.
    Fórmula:C129H207N45O41S3
    Pureza:98.24%
    Forma y color:Solid
    Peso molecular:3140.5

    Ref: TM-TP1220L

    1mg
    185,00€
    5mg
    459,00€
    10mg
    657,00€
    25mg
    1.026,00€
    50mg
    1.388,00€
    100mg
    1.872,00€
    200mg
    2.527,00€
  • Macitentan

    CAS:
    Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).
    Fórmula:C19H20Br2N6O4S
    Pureza:98% - >99.99%
    Forma y color:Solid
    Peso molecular:588.27

    Ref: TM-T2561

    10mg
    44,00€
    25mg
    52,00€
    50mg
    56,00€
    100mg
    84,00€
    500mg
    170,00€
    1mL*10mM (DMSO)
    40,00€
  • Endothelin-2 (49-69), human

    CAS:
    Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
    Fórmula:C115H160N26O32S4
    Pureza:98.26%
    Forma y color:Solid
    Peso molecular:2546.92

    Ref: TM-TP1174

    1mg
    188,00€
    5mg
    405,00€
    10mg
    562,00€
    25mg
    843,00€
    50mg
    A consultar
  • Nebentan potassium

    CAS:
    Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.
    Fórmula:C24H20KN5O5S
    Pureza:99.05%
    Forma y color:Solid
    Peso molecular:529.61

    Ref: TM-T36008

    1mg
    55,00€
    2mg
    81,00€
    5mg
    117,00€
    10mg
    187,00€
    25mg
    329,00€
    50mg
    530,00€
    100mg
    718,00€
    200mg
    938,00€
    1mL*10mM (DMSO)
    140,00€
  • Zibotentan

    CAS:
    Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
    Fórmula:C19H16N6O4S
    Pureza:97.00% - 97.02%
    Forma y color:Solid
    Peso molecular:424.43

    Ref: TM-T6258

    1mg
    43,00€
    2mg
    57,00€
    5mg
    92,00€
    10mg
    144,00€
    25mg
    283,00€
    50mg
    A consultar
    1mL*10mM (DMSO)
    93,00€
  • TBC3711

    CAS:
    TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.
    Fórmula:C20H21N3O5S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:447.53

    Ref: TM-T15232

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • ZD-1611

    CAS:
    ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.
    Fórmula:C22H24N4O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:456.51

    Ref: TM-T17287

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • CH 141

    CAS:
    CH 141 is a new type of peripheral vasodilator.
    Fórmula:C19H21N3O
    Forma y color:Solid
    Peso molecular:307.39

    Ref: TM-T30859

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • ABT-546

    CAS:
    ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.
    Fórmula:C30H48N2O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:532.71

    Ref: TM-T10225

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • BMS-193884

    CAS:
    BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.
    Fórmula:C20H17N3O4S
    Forma y color:Solid
    Peso molecular:395.43

    Ref: TM-T30501

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • CI 1020

    CAS:
    endothelin-A receptor (ETA) antagonist
    Fórmula:C28H26O9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:506.5

    Ref: TM-T22663

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • PD-156707

    CAS:
    PD-156707 is a selective antagonist of endothelin A receptor.
    Fórmula:C28H26NaO9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:529.497

    Ref: TM-T28343

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • WS 009B

    CAS:
    WS 009B is an antagonist of the endothelin receptor.
    Fórmula:C24H25NO11S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:535.52

    Ref: TM-T24081

    25mg
    1.369,00€
  • Daglutril

    CAS:
    Daglutril is a NEP/ECE inhibitor for treating hypertension, heart failure, and pulmonary issues, blocking big endothelin-1 conversion.
    Fórmula:C31H38N2O6
    Forma y color:Solid
    Peso molecular:534.64

    Ref: TM-T27119

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Atrasentan hydrochloride

    CAS:
    Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).
    Fórmula:C29H39ClN2O6
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:547.08

    Ref: TM-TQ0270

    1mg
    49,00€
    5mg
    97,00€
    10mg
    137,00€
    25mg
    264,00€
    50mg
    376,00€
    1mL*10mM (DMSO)
    116,00€
  • Avosentan

    CAS:
    Avosentan(Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.
    Fórmula:C23H21N5O5S
    Pureza:98.31% - 99.47%
    Forma y color:Solid
    Peso molecular:479.51

    Ref: TM-TQ0282

    1mg
    38,00€
    5mg
    80,00€
    10mg
    101,00€
    25mg
    205,00€
    50mg
    356,00€
    100mg
    522,00€
    1mL*10mM (DMSO)
    84,00€
  • PD-159020

    CAS:
    PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).
    Fórmula:C32H25NO8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:551.54

    Ref: TM-T12382

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • WS 009A

    CAS:
    WS 009A is an antagonist of the endothelin receptor.
    Fórmula:C24H25NO10S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:519.52

    Ref: TM-T24053

    25mg
    1.444,00€
  • ETA antagonist 1

    CAS:
    ETA antagonist 1 is an antagonist of ETA selective (IC50 of 0.08 μM).
    Fórmula:C20H25N3O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:387.5

    Ref: TM-T12157

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Aminaftone

    CAS:
    Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.
    Fórmula:C18H15NO4
    Pureza:96.31% - 99.39%
    Forma y color:Solid
    Peso molecular:309.32

    Ref: TM-T14219

    1mg
    200,00€
    5mg
    552,00€
    10mg
    685,00€
    25mg
    905,00€
  • FR 139317

    CAS:
    highly potent and selective ETA endothelin receptor antagonist
    Fórmula:C33H44N6O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:604.74

    Ref: TM-T22791

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • BMS 182874

    CAS:
    BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.
    Fórmula:C17H19N3O3S
    Pureza:99.73%
    Forma y color:Solid
    Peso molecular:345.42

    Ref: TM-T26841

    1mg
    35,00€
    5mg
    74,00€
    10mg
    109,00€
    25mg
    182,00€
    50mg
    259,00€
    100mg
    356,00€
    200mg
    490,00€
  • Edonentan

    CAS:
    Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.
    Fórmula:C28H32N4O5S
    Pureza:98.07% - 99.6%
    Forma y color:Solid
    Peso molecular:536.64

    Ref: TM-T31605

    1mg
    563,00€
    5mg
    1.121,00€
    10mg
    1.254,00€
    25mg
    1.434,00€
  • SB-209670

    CAS:
    SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.
    Fórmula:C29H28O9
    Pureza:98.29% - 99.40%
    Forma y color:Solid
    Peso molecular:520.53

    Ref: TM-T34541

    1mg
    333,00€
    5mg
    787,00€
    10mg
    1.074,00€
    25mg
    1.510,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
    500mg
    4.655,00€
    1mL*10mM (DMSO)
    797,00€
  • Sitaxsentan

    CAS:
    Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.
    Fórmula:C18H15ClN2O6S2
    Pureza:97.99% - 98.71%
    Forma y color:Solid
    Peso molecular:454.9

    Ref: TM-T12924

    1mg
    270,00€
    5mg
    700,00€
    10mg
    900,00€
    25mg
    1.170,00€
    50mg
    1.440,00€
    100mg
    1.800,00€
    500mg
    3.600,00€
  • L-749329

    CAS:
    L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.
    Fórmula:C28H29NO8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:539.6

    Ref: TM-T27776

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • Clazosentan

    CAS:
    Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.
    Fórmula:C25H23N9O6S
    Pureza:95.39% - >99.99%
    Forma y color:Solid
    Peso molecular:577.57

    Ref: TM-T64084

    1mg
    79,00€
    5mg
    178,00€
    10mg
    279,00€
    25mg
    628,00€
    50mg
    1.017,00€
    100mg
    1.311,00€
    200mg
    1.768,00€
    1mL*10mM (DMSO)
    230,00€
  • K-8794

    CAS:
    K-8794 is an orally active and selective endothelin receptor ETB antagonist that can be utilized in cardiovascular disease research.
    Fórmula:C36H38N6O6S
    Forma y color:Solid
    Peso molecular:682.789

    Ref: TM-T204123

    10mg
    A consultar
    50mg
    A consultar
  • Edonentan hydrate

    CAS:
    Edonentan (BMS 207940) hydrate effectively blocks the endothelin A (ETA) receptor as a potent and selective antagonist, featuring a K i of 10 pM. It exhibits complete (100%) oral bioavailability in rats [1].
    Fórmula:C28H34N4O6S
    Forma y color:Solid
    Peso molecular:554.66

    Ref: TM-T86338

    25mg
    1.690,00€
    50mg
    2.210,00€
    100mg
    2.879,00€
  • Diosuxentan

    CAS:
    Diosuxentan is an inhibitor of ETA and is utilized in research pertaining to cardiovascular, renal, and neuronal inflammatory diseases.
    Fórmula:C20H21BrN6O7S
    Forma y color:Solid
    Peso molecular:569.39

    Ref: TM-T211846

    10mg
    A consultar
    50mg
    A consultar
  • BMS-248360

    CAS:
    BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.
    Fórmula:C36H45N5O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:659.84

    Ref: TM-T14672

    25mg
    A consultar
    50mg
    A consultar
    100mg
    A consultar
  • JKC 302

    CAS:
    JKC 302 is an ET-A receptor antagonist that partially inhibits the contraction of tracheal rings in asthmatic rats induced by ET-1.
    Fórmula:C30H42N6O6
    Forma y color:Solid
    Peso molecular:582.69

    Ref: TM-TP3818

    10mg
    A consultar
    50mg
    A consultar
  • Macitentan (n-butyl analogue)

    CAS:
    Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.
    Fórmula:C20H21Br2N5O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:587.29

    Ref: TM-T11935

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • IRL 2500

    CAS:
    IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.
    Fórmula:C36H35N3O4
    Pureza:99.36%
    Forma y color:White Crystalline Solid
    Peso molecular:573.68

    Ref: TM-T15596

    2mg
    42,00€
    5mg
    60,00€
    10mg
    87,00€
    25mg
    172,00€
    50mg
    250,00€
    100mg
    350,00€
    1mL*10mM (DMSO)
    73,00€
  • Tezosentan

    CAS:
    Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).
    Fórmula:C27H27N9O6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:605.63

    Ref: TM-T17064

    25mg
    2.025,00€
    50mg
    2.737,00€
    100mg
    3.565,00€
  • BQ-788

    CAS:
    BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.
    Fórmula:C34H51N5O7
    Pureza:98.81%
    Forma y color:Solid
    Peso molecular:641.8

    Ref: TM-T10595

    1mg
    137,00€
    2mg
    188,00€
    5mg
    329,00€
    10mg
    472,00€
    25mg
    753,00€
    50mg
    1.017,00€
    100mg
    1.378,00€
    500mg
    2.737,00€
    1mL*10mM (DMSO)
    360,00€
  • Patecibart

    CAS:

    Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).

    Pureza:98%
    Forma y color:Liquid

    Ref: TM-T81538

    ne
    Descatalogado
    1mg
    Descatalogado
    5mg
    Descatalogado
    50mg
    Descatalogado
    Producto descatalogado