Receptor de endotelina
Los receptores de endotelina son GPCR que median los efectos de las endotelinas, péptidos vasoconstrictores potentes que desempeñan un papel significativo en la regulación del tono vascular, el control de la presión arterial y la proliferación celular. Los antagonistas de los receptores de endotelina se utilizan en el tratamiento de afecciones como la hipertensión arterial pulmonar y la insuficiencia cardíaca. Estos receptores también son objetivos importantes en la investigación sobre enfermedades cardiovasculares y cáncer. En CymitQuimica, ofrecemos una selección de moduladores de receptores de endotelina de alta calidad para apoyar su investigación en biología cardiovascular, oncología y fisiología vascular.
Se han encontrado 76 productos de "Receptor de endotelina"
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ANP(1-28) Acetate (human, porcine)
CAS:<p>Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.</p>Fórmula:C129H207N45O41S3Pureza:98.24%Forma y color:SolidPeso molecular:3140.5RO 46-8443
CAS:<p>RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.</p>Fórmula:C31H35N3O8SPureza:98.77% - 99.77%Forma y color:SolidPeso molecular:609.69Ambrisentan
CAS:<p>Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not linked to acute liver injury.</p>Fórmula:C22H22N2O4Pureza:99.65% - 99.86%Forma y color:SolidPeso molecular:378.42Ro 46-2005
CAS:<p>Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 nM).</p>Fórmula:C23H27N3O6SPureza:98.02% - 98.8%Forma y color:SolidPeso molecular:473.54Bosentan
CAS:<p>Bosentan is a competitive endothelin receptor antagonist, used for treating pulmonary arterial hypertension.</p>Fórmula:C27H29N5O6SPureza:99.74% - 99.84%Forma y color:Pale Yellow To Off-White SolidPeso molecular:551.614Nebentan potassium
CAS:<p>Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.</p>Fórmula:C24H20KN5O5SPureza:99.05%Forma y color:SolidPeso molecular:529.61Zibotentan
CAS:<p>Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.</p>Fórmula:C19H16N6O4SPureza:97.00% - 97.02%Forma y color:SolidPeso molecular:424.43CH 141
CAS:<p>CH 141 is a new type of peripheral vasodilator.</p>Fórmula:C19H21N3OForma y color:SolidPeso molecular:307.39ZD-1611
CAS:<p>ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.</p>Fórmula:C22H24N4O5SPureza:98%Forma y color:SolidPeso molecular:456.51WS 009B
CAS:<p>WS 009B is an antagonist of the endothelin receptor.</p>Fórmula:C24H25NO11SPureza:98%Forma y color:SolidPeso molecular:535.52Daglutril
CAS:<p>Daglutril is a NEP/ECE inhibitor for treating hypertension, heart failure, and pulmonary issues, blocking big endothelin-1 conversion.</p>Fórmula:C31H38N2O6Forma y color:SolidPeso molecular:534.64WS 009A
CAS:<p>WS 009A is an antagonist of the endothelin receptor.</p>Fórmula:C24H25NO10SPureza:98%Forma y color:SolidPeso molecular:519.52ETA antagonist 1
CAS:<p>ETA antagonist 1 is an antagonist of ETA selective (IC50 of 0.08 μM).</p>Fórmula:C20H25N3O3SPureza:98%Forma y color:SolidPeso molecular:387.5Aminaftone
CAS:<p>Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.</p>Fórmula:C18H15NO4Pureza:96.31% - 99.39%Forma y color:SolidPeso molecular:309.32Atrasentan hydrochloride
CAS:<p>Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).</p>Fórmula:C29H39ClN2O6Pureza:99.75%Forma y color:SolidPeso molecular:547.08PD-156707
CAS:<p>PD-156707 is a selective antagonist of endothelin A receptor.</p>Fórmula:C28H26NaO9Pureza:98%Forma y color:SolidPeso molecular:529.497CI 1020
CAS:<p>endothelin-A receptor (ETA) antagonist</p>Fórmula:C28H26O9Pureza:98%Forma y color:SolidPeso molecular:506.5TBC3711
CAS:<p>TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.</p>Fórmula:C20H21N3O5S2Pureza:98%Forma y color:SolidPeso molecular:447.53BMS-193884
CAS:<p>BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.</p>Fórmula:C20H17N3O4SForma y color:SolidPeso molecular:395.43PD-159020
CAS:<p>PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).</p>Fórmula:C32H25NO8Pureza:98%Forma y color:SolidPeso molecular:551.54
