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Receptor de histamina

Receptor de histamina

Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.

Se han encontrado 358 productos de "Receptor de histamina"

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  • GSK 189254 HCl

    CAS:
    <p>GSK 189254A: histamine H3 antagonist, treats narcolepsy, may improve cognition and help with dementia, neuropathic pain.</p>
    Fórmula:C21H26ClN3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:387.9
  • GSK334429

    CAS:
    <p>GSK334429 is an antagonist of histamine H3 receptor.</p>
    Fórmula:C20H29F3N4O
    Forma y color:Solid
    Peso molecular:398.47
  • Sequifenadine

    CAS:
    <p>Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].</p>
    Fórmula:C22H27NO
    Forma y color:Solid
    Peso molecular:321.46
  • A-940894

    CAS:
    <p>A-940894: Potent H4 receptor antagonist, anti-inflammatory, binds well to human/rat H4, low affinity for H1/H2/H3, good pharmacokinetics.</p>
    Fórmula:C17H21N5
    Forma y color:Solid
    Peso molecular:295.38
  • Loratadine N-oxide

    CAS:
    <p>Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine.</p>
    Fórmula:C22H23ClN2O3
    Forma y color:Solid
    Peso molecular:398.88
  • MK-0249

    CAS:
    <p>MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).</p>
    Fórmula:C23H24F3N3O2
    Pureza:99.90%
    Forma y color:Solid
    Peso molecular:431.45
  • N-Acetylhistamine

    CAS:
    <p>N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine.</p>
    Fórmula:C7H11N3O
    Pureza:99.51%
    Forma y color:Solid
    Peso molecular:153.18
  • Izuforant

    CAS:
    <p>Izuforant (JW1601) has anti-inflammatory effects, binds h5-HT3R (IC50: 9.1 μM), and blocks H4R orally (IC50: 36 nM).</p>
    Fórmula:C12H12BrN7
    Forma y color:Solid
    Peso molecular:334.17
  • A-943931

    CAS:
    <p>A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.</p>
    Fórmula:C17H21N5
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:295.38
  • Pitolisant oxalate

    CAS:
    <p>Pitolisant oxalate is a potent and selective inverse agonist of nonimidazole at the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>
    Fórmula:C19H28ClNO5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:385.88
  • Pirolate

    CAS:
    <p>Pirolate is a receptor of histamine H1.</p>
    Fórmula:C16H15N3O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:329.31
  • Bepotastine tosylate

    CAS:
    <p>Bepotastine tosylate: Oral 2nd-gen H1 antagonist, inhibits histamine effects on NGF; treats conjunctivitis, urticaria.</p>
    Fórmula:C28H33ClN2O6S
    Forma y color:Solid
    Peso molecular:561.09
  • VUF-10497

    CAS:
    <p>VUF-10497: H4 receptor inverse agonist, anti-inflammatory in rats, binds human H1 receptor (pKi=7.57).</p>
    Fórmula:C18H20ClN5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:373.9
  • A331440

    CAS:
    <p>A331440 is an modulator of L-histidine and histamine H3 receptor.</p>
    Fórmula:C22H27N3O
    Forma y color:Solid
    Peso molecular:349.47
  • Phenindamine

    CAS:
    <p>Phenindamine (Nu 1504) is an H1-receptor antagonist which is antihistamine[1].</p>
    Fórmula:C19H19N
    Forma y color:Solid
    Peso molecular:261.36
  • Acreozast

    CAS:
    <p>Acreozast, a histamine release inhibitor, is used potentially for the treatment of asthma and atopic dermatitis.</p>
    Fórmula:C15H14ClN3O6
    Forma y color:Solid
    Peso molecular:367.74
  • CP19

    CAS:
    <p>CP19 blocks histamine receptors; inhibits EBOV and MARV with IC50s of 3.4 μM and 29.5 μM, respectively; antiviral [1].</p>
    Fórmula:C26H30N2O5
    Forma y color:Solid
    Peso molecular:450.53
  • Phenindamine Tartrate

    CAS:
    <p>Phenindamine Tartrate, an antihistamine and anticholinergic, treats colds and allergies like sneezing and rashes.</p>
    Fórmula:C23H25NO6
    Forma y color:Solid
    Peso molecular:411.454
  • INCB38579

    CAS:
    <p>INCB38579: Oral, selective H4 antagonist; crosses brain barrier; IC50s - hH4R: 4.8 nM, mH4R: 42 nM, rH4R: 32 nM; anti-inflammatory and antipruritic.</p>
    Fórmula:C25H34N6O
    Forma y color:Solid
    Peso molecular:434.58
  • Thioperamide

    CAS:
    <p>histamine H3 and H4 antagonist/inverse agonist</p>
    Fórmula:C15H24N4S
    Pureza:98%
    Forma y color:White Solid
    Peso molecular:292.44