
Receptor de histamina
Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.
Se han encontrado 358 productos de "Receptor de histamina"
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GSK 189254 HCl
CAS:<p>GSK 189254A: histamine H3 antagonist, treats narcolepsy, may improve cognition and help with dementia, neuropathic pain.</p>Fórmula:C21H26ClN3O2Pureza:98%Forma y color:SolidPeso molecular:387.9GSK334429
CAS:<p>GSK334429 is an antagonist of histamine H3 receptor.</p>Fórmula:C20H29F3N4OForma y color:SolidPeso molecular:398.47Sequifenadine
CAS:<p>Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].</p>Fórmula:C22H27NOForma y color:SolidPeso molecular:321.46A-940894
CAS:<p>A-940894: Potent H4 receptor antagonist, anti-inflammatory, binds well to human/rat H4, low affinity for H1/H2/H3, good pharmacokinetics.</p>Fórmula:C17H21N5Forma y color:SolidPeso molecular:295.38Loratadine N-oxide
CAS:<p>Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine.</p>Fórmula:C22H23ClN2O3Forma y color:SolidPeso molecular:398.88MK-0249
CAS:<p>MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).</p>Fórmula:C23H24F3N3O2Pureza:99.90%Forma y color:SolidPeso molecular:431.45N-Acetylhistamine
CAS:<p>N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine.</p>Fórmula:C7H11N3OPureza:99.51%Forma y color:SolidPeso molecular:153.18Izuforant
CAS:<p>Izuforant (JW1601) has anti-inflammatory effects, binds h5-HT3R (IC50: 9.1 μM), and blocks H4R orally (IC50: 36 nM).</p>Fórmula:C12H12BrN7Forma y color:SolidPeso molecular:334.17A-943931
CAS:<p>A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.</p>Fórmula:C17H21N5Pureza:99.79%Forma y color:SolidPeso molecular:295.38Pitolisant oxalate
CAS:<p>Pitolisant oxalate is a potent and selective inverse agonist of nonimidazole at the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>Fórmula:C19H28ClNO5Pureza:98%Forma y color:SolidPeso molecular:385.88Pirolate
CAS:<p>Pirolate is a receptor of histamine H1.</p>Fórmula:C16H15N3O5Pureza:98%Forma y color:SolidPeso molecular:329.31Bepotastine tosylate
CAS:<p>Bepotastine tosylate: Oral 2nd-gen H1 antagonist, inhibits histamine effects on NGF; treats conjunctivitis, urticaria.</p>Fórmula:C28H33ClN2O6SForma y color:SolidPeso molecular:561.09VUF-10497
CAS:<p>VUF-10497: H4 receptor inverse agonist, anti-inflammatory in rats, binds human H1 receptor (pKi=7.57).</p>Fórmula:C18H20ClN5SPureza:98%Forma y color:SolidPeso molecular:373.9A331440
CAS:<p>A331440 is an modulator of L-histidine and histamine H3 receptor.</p>Fórmula:C22H27N3OForma y color:SolidPeso molecular:349.47Phenindamine
CAS:<p>Phenindamine (Nu 1504) is an H1-receptor antagonist which is antihistamine[1].</p>Fórmula:C19H19NForma y color:SolidPeso molecular:261.36Acreozast
CAS:<p>Acreozast, a histamine release inhibitor, is used potentially for the treatment of asthma and atopic dermatitis.</p>Fórmula:C15H14ClN3O6Forma y color:SolidPeso molecular:367.74CP19
CAS:<p>CP19 blocks histamine receptors; inhibits EBOV and MARV with IC50s of 3.4 μM and 29.5 μM, respectively; antiviral [1].</p>Fórmula:C26H30N2O5Forma y color:SolidPeso molecular:450.53Phenindamine Tartrate
CAS:<p>Phenindamine Tartrate, an antihistamine and anticholinergic, treats colds and allergies like sneezing and rashes.</p>Fórmula:C23H25NO6Forma y color:SolidPeso molecular:411.454INCB38579
CAS:<p>INCB38579: Oral, selective H4 antagonist; crosses brain barrier; IC50s - hH4R: 4.8 nM, mH4R: 42 nM, rH4R: 32 nM; anti-inflammatory and antipruritic.</p>Fórmula:C25H34N6OForma y color:SolidPeso molecular:434.58Thioperamide
CAS:<p>histamine H3 and H4 antagonist/inverse agonist</p>Fórmula:C15H24N4SPureza:98%Forma y color:White SolidPeso molecular:292.44
