Receptor de histamina
Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.
Se han encontrado 358 productos de "Receptor de histamina"
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FR-A 19
CAS:<p>FR-A 19: Histamine H2 agonist, nanomolar inhibition of basophil histamine release; potent anti-allergic.</p>Fórmula:C25H34Cl3F2N5Forma y color:SolidPeso molecular:548.93VUF 8328
CAS:<p>VUF 8328 is an agonist of histamine H(3) receptor.</p>Fórmula:C7H12N4SPureza:98%Forma y color:SolidPeso molecular:184.26Adriforant
CAS:<p>Adriforant (PF-3893787,ZPL-3893797) is a competitive histamine receptor 4 h4 antagonist that antagonizes histamine-induced phosphorylation of ERK, inflammation.</p>Fórmula:C13H22N6Pureza:99.84%Forma y color:SolidPeso molecular:262.35FRG8701
CAS:<p>FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.</p>Fórmula:C22H30N2O4SPureza:98%Forma y color:SolidPeso molecular:418.55ReN-1869 hydrochloride
CAS:<p>ReN 1869 hydrochloride is a novel, selective antagonist of histamine H1 receptor.</p>Fórmula:C24H28ClNO2Pureza:98%Forma y color:SolidPeso molecular:397.94H4R antagonist 1
CAS:<p>H4R antagonist 1: selective histamine H4R inhibitor, IC50 27 nM, no affinity for H1R, H2R, H3R.</p>Fórmula:C11H11BrN8Forma y color:SolidPeso molecular:335.16(±)-Tazifylline
CAS:<p>(±)-Tazifylline is a selective and long-acting antagonist of histamine H1 receptor.</p>Fórmula:C23H32N6O3SPureza:99.54%Forma y color:SolidPeso molecular:472.6Noberastine
CAS:<p>Noberastine (R 64947) is a novel histamine H1 antagonist with potent and specific peripheral antihistamine activity.</p>Fórmula:C17H21N5OPureza:99.72% - >99.99%Forma y color:SolidPeso molecular:311.38KSK68
CAS:<p>KSK68 is a sigma-1 and histamine H3 receptor antagonist with analgesic activity, inhibits H3 receptors and can be used to study pain.</p>Fórmula:C23H28N2O2Pureza:99.11%Forma y color:SolidPeso molecular:364.48Immethridine dihydrobromide
CAS:<p>Immethridine dihydrobromide is a histamine H3 receptor agonist.</p>Fórmula:C9H11Br2N3Pureza:97.61% - 98.14%Forma y color:SolidPeso molecular:321.01D18024
CAS:<p>D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.</p>Fórmula:C29H31ClFN3OPureza:99.86%Forma y color:SolidPeso molecular:492.03Impromidine hydrochloride
CAS:<p>Impromidine hydrochloride is a very potent and specific histamine H2 receptor agonist for conducting cardiovascular studies.</p>Fórmula:C14H26Cl3N7SPureza:99.82%Forma y color:SolidPeso molecular:430.83Enerisant hydrochloride
CAS:<p>Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteins</p>Fórmula:C22H31ClN4O3Pureza:99.95%Forma y color:SolidPeso molecular:434.96Linetastine
CAS:<p>Linetastine (TMK-688) inhibits 5-LOX, blocks leukotrienes, counters histamine; researched for asthma, atherosclerosis, ulcers.</p>Fórmula:C35H40N2O6Pureza:99.76%Forma y color:SolidPeso molecular:584.7Pitolisant
CAS:<p>Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>Fórmula:C17H26ClNOPureza:99.84%Forma y color:SolidPeso molecular:295.85KSK94
CAS:<p>KSK94 is an H3 receptor antagonist that inhibits sigma-2 receptors , with a Ki value of 75.2 nM, and can be used to study injurious pain.</p>Fórmula:C25H26N4OPureza:99.60%Forma y color:SolidPeso molecular:398.5Irdabisant
CAS:<p>Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.</p>Fórmula:C18H23N3O2Pureza:99.96%Forma y color:SolidPeso molecular:313.39Efletirizine
CAS:<p>Efletirizine (UCB-28754), a histamine blocker and 5-LO inhibitor, aids in topical allergy treatment.</p>Fórmula:C21H24F2N2O3Pureza:99.39%Forma y color:SolidPeso molecular:390.42Antihistamine-1
CAS:<p>Antihistamine-1 是能够渗透血脑屏障的 H1-抗组胺药 (Ki=6.9 nM), 它也是 CYP2D6 和 hERG 通道的抑制剂，其 IC50 值分别为 5.4 和 0.8 μM。</p>Fórmula:C23H24FN5Pureza:99.69%Forma y color:SolidPeso molecular:389.47NP10679
CAS:<p>NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.</p>Fórmula:C23H26F3N3O3Pureza:99.43%Forma y color:SolidPeso molecular:449.47
