Receptor de histamina
Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.
Se han encontrado 358 productos de "Receptor de histamina"
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H3 receptor antagonist 1
CAS:<p>H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.</p>Fórmula:C20H28F2N2OPureza:98%Forma y color:SolidPeso molecular:350.45H4R antagonist 2
CAS:<p>H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoid</p>Fórmula:C13H17N5OPureza:98%Forma y color:SolidPeso molecular:259.31Cipralisant
CAS:<p>Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.</p>Fórmula:C14H20N2Pureza:98%Forma y color:SolidPeso molecular:216.32Levocabastine hydrochloride
CAS:<p>Levocabastine HCl is an agent with antihistaminic activity.</p>Fórmula:C26H30ClFN2O2Forma y color:SolidPeso molecular:456.98ST-1006
CAS:<p>ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.</p>Fórmula:C16H20Cl2N6Pureza:98.87% - 99.96%Forma y color:SolidPeso molecular:367.28Enerisant
CAS:<p>Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.</p>Fórmula:C22H30N4O3Pureza:99.7%Forma y color:SoildPeso molecular:398.50Tixanox sodium
CAS:<p>Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.</p>Fórmula:C15H9NaO5SForma y color:SolidPeso molecular:324.28CI-624
CAS:<p>CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.</p>Fórmula:C8H8N2SForma y color:SolidPeso molecular:164.228H3R antagonist 5
CAS:<p>H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.</p>Fórmula:C23H32N2O4Forma y color:SolidPeso molecular:400.511Arpromidine
CAS:<p>Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.</p>Fórmula:C21H25FN6Forma y color:SolidPeso molecular:380.462H1R ligand-1
CAS:<p>H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.</p>Fórmula:C19H23NOForma y color:SolidPeso molecular:281.392Nedocromil sodium
CAS:<p>Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.</p>Fórmula:C19H17NNaO7Pureza:98%Forma y color:SolidPeso molecular:394.335UR-AK49
CAS:<p>UR-AK49 (compound 11) is an agonist for the human histamine H1 and H2 receptors. It exhibits an EC50 of 23 nM in the GTPase assay involving hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 is applicable in neurologically related research.</p>Fórmula:C16H27N5OForma y color:SolidPeso molecular:305.42FR-145715
CAS:<p>FR-145715 is a histamine H2 receptor antagonist characterized by its specific anti-Helicobacter pylori activity. This compound is utilized in the study of gastric lesions.</p>Fórmula:C16H21N5O2SForma y color:SolidPeso molecular:347.44Histamine H3 antagonist-1
CAS:<p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>Fórmula:C24H28F3N3O2Forma y color:SolidPeso molecular:447.49H3R antagonist 1
CAS:<p>H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).</p>Fórmula:C19H23N3O3Forma y color:SolidPeso molecular:341.4(R)-(-)-α-Methylhistamine dihydrochloride
CAS:<p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>Fórmula:C6H13Cl2N3Forma y color:SolidPeso molecular:198.09Imetit dihydrobromide
CAS:<p>Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).</p>Fórmula:C6H12Br2N4SPureza:98%Forma y color:SolidPeso molecular:332.06
