Receptor de histamina
Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.
Se han encontrado 381 productos de "Receptor de histamina"
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Hydroxyzine-d8 DiHCl
CAS:Hydroxyzine-d8 DiHCl is a deuterated compound of Hydroxyzine DiHCl. Hydroxyzine DiHCl has a CAS number of 2192-20-3.Fórmula:C21H21D8Cl3N2O2Forma y color:SolidPeso molecular:455.88Methaphenilene hydrochloride
CAS:Methaphenilene hydrochloride is an H1 receptor antagonist with antihistaminic and anticholinergic activity, in allergic inflammation and autonomic research.Fórmula:C15H21ClN2SPureza:99.84%Forma y color:SolidPeso molecular:296.86Mianserin-d3
CAS:Mianserin-d3 is a deuterated compound of Mianserin. Mianserin has a CAS number of 24219-97-4. Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family. Mianserin has antidepressant, antianxiety, antiemetic, hypotrophic, hypnotic and antihistamine effects, and can be used as a combination of norepinephrine and specific serotonin to treat depression.Fórmula:C18H17D3N2Forma y color:SolidPeso molecular:267.38Roxatidine acetate
CAS:Roxatidine acetate: anti-ulcer, blocks histamine, reduces acid. Safer at lower doses.Fórmula:C19H28N2O4Pureza:98%Forma y color:White Or Off-White PowderPeso molecular:348.44Amthamine
CAS:Compound AMTHAMINE DIHYDROBROMIDE is a useful organic compound for research related to life sciences.Fórmula:C6H11N3SForma y color:SoildPeso molecular:157.24Proxyfan Oxalate
CAS:Proxyfan Oxalate is a potent antagonist of the histamine H3 receptor (histamine H3 receptor), with Ki values of 2.9 nM for rats and 2.7 nM for humans. Its inhibitory effect on H3 receptors is over 1000 times stronger than its effect on other histamine receptors.Fórmula:C15H18N2O5Forma y color:SolidPeso molecular:306.31Ciproxifan
CAS:Ciproxifan (FUB-359) is a highly effective and specific histamin H3-receptor antagonist (IC50: 9.2 nM).Fórmula:C16H18N2O2Pureza:98.00%Forma y color:SolidPeso molecular:270.33Lodoxamide tromethamine
CAS:<p>Lodoxamide tromethamine is a mast cell stabilizer with anti-allergic properties and can be used in studies about the treatment of asthma and allergic</p>Fórmula:C19H28ClN5O12Pureza:98.8%Forma y color:SolidPeso molecular:553.91PF-03654746
CAS:PF-03654746: selective H3 antagonist, boosts cognition in Alzheimer's, may treat allergic rhinitis.Fórmula:C18H24F2N2OPureza:98.85% - 99.57%Forma y color:SolidPeso molecular:322.39A 987306
CAS:<p>A-987306: Potent, oral histamine H4 antagonist; Ki: 3.4 nM (rat), 5.8 nM (human); reduces inflammation in mouse peritonitis.</p>Fórmula:C18H25N5OForma y color:SolidPeso molecular:327.42FRG8701
CAS:FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.Fórmula:C22H30N2O4SPureza:98%Forma y color:SolidPeso molecular:418.55Nedocromil
CAS:Nedocromil (FPL 59002) inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).Fórmula:C19H17NO7Pureza:95% - 97.34%Forma y color:SolidPeso molecular:371.34H3R-IN-1 Hydrochloride
CAS:H3R-IN-1 Hydrochloride is an inverse agonist of histamine receptor 3( H3R ) .Fórmula:C19H24ClN3O3Pureza:98%Forma y color:SolidPeso molecular:377.86Carcinine
CAS:Carcinine ditrifluoroacetate is a H3 receptor antagonist.Fórmula:C8H14N4OPureza:98%Forma y color:SolidPeso molecular:182.22Setastine HCl
CAS:<p>Setastine HCl is a potent antagonist of histamine H1-receptor mediated responses.</p>Fórmula:C22H29Cl2NOForma y color:SolidPeso molecular:394.38Carbinoxamine
CAS:Carbinoxamine: antihistamine for hay fever, angioedema, rhinitis, mild urticaria, dermatographism, allergic conjunctivitis; an H1-antagonist.Fórmula:C16H19ClN2OPureza:98%Forma y color:LiquidPeso molecular:290.79AZD5213
CAS:AZD5213: selective human H3 receptor antagonist, pKi 9.3, for sleep/cognition research.Fórmula:C19H25N3O2Forma y color:SolidPeso molecular:327.42ROS 234
CAS:ROS 234 is a potent H3 antagonist with pKB 9.46 for Guinea-pig ileum and pKi 8.90 for Rat cortex; ED50 of 19.12 mg/kg in rats, but with limited central access.Fórmula:C13H15N5Forma y color:SolidPeso molecular:241.29JNJ 10181457 dihydrochloride
CAS:JNJ 10181457 dihydrochloride is a Histamine H3 receptor antagonist.Fórmula:C20H28N2OPureza:98%Forma y color:SolidPeso molecular:312.45OUP-186
CAS:OUP-186 is a selective H3 receptor antagonist that suppresses breast cancer cell growth with an IC50 of ~50 μM and induces apoptosis.Fórmula:C19H30ClN3SForma y color:SolidPeso molecular:367.98A-304121
CAS:A-304121 is a histamine H(3) receptor.Fórmula:C20H29N3O3Forma y color:SolidPeso molecular:359.46(R)-Mequitazine
CAS:<p>(R)-Mequitazine, a muscarinic acetylcholine receptor (M-AChRs) antagonist, is used potentially for the treatment of asthma.</p>Fórmula:C20H22N2SForma y color:SolidPeso molecular:322.47ABT-239
CAS:ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.Fórmula:C22H22N2OPureza:99.94%Forma y color:SolidPeso molecular:330.42Zolantidine dimaleate
CAS:H2 receptor antagonistFórmula:C26H31N3O5SPureza:98%Forma y color:SolidPeso molecular:497.61Aminopotentidine
CAS:H2 antagonistFórmula:C26H35N7O2Pureza:98%Forma y color:SolidPeso molecular:477.6Alimemazine
CAS:Alimemazine, an antipruritic and HA-receptor antagonist, also partially activates H1R and other GPCRs.Fórmula:C18H22N2SPureza:98%Forma y color:Crystals SolidPeso molecular:298.45JNJ-10191584
CAS:JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammationFórmula:C13H15ClN4OForma y color:SolidPeso molecular:278.74Zaltidine
CAS:Zaltidine is an antagonist of H2-receptor, and has the antisecretory action.Fórmula:C8H10N6SPureza:98%Forma y color:SolidPeso molecular:222.27Adriforant
CAS:Adriforant (PF-3893787,ZPL-3893797) is a competitive histamine receptor 4 h4 antagonist that antagonizes histamine-induced phosphorylation of ERK, inflammation.Fórmula:C13H22N6Pureza:99.84%Forma y color:SolidPeso molecular:262.35VUF 8328
CAS:VUF 8328 is an agonist of histamine H(3) receptor.Fórmula:C7H12N4SPureza:98%Forma y color:SolidPeso molecular:184.26FR-A 19
CAS:FR-A 19: Histamine H2 agonist, nanomolar inhibition of basophil histamine release; potent anti-allergic.Fórmula:C25H34Cl3F2N5Forma y color:SolidPeso molecular:548.93S-1-Propenyl-L-cysteine
CAS:S-1-Propenyl-L-cysteine, a stereoisomer of S-allyl-l-cysteine, exhibits immunomodulatory effects and has been shown to decrease blood pressure in hypertensiveFórmula:C6H11NO2SPureza:98%Forma y color:SolidPeso molecular:161.22UR-PI376
CAS:UR-PI376 is a selective histamine H4 receptor agonist with low H1/H2 activity and moderate H3 affinity.Fórmula:C17H22N6SForma y color:SolidPeso molecular:342.46Impromidine
CAS:Impromidine is a highly potent and specific agonist of the histamine H2 receptor.Fórmula:C14H23N7SPureza:98%Forma y color:SolidPeso molecular:321.44Azatadine
CAS:Azatadine is histamine and cholinergic inhibitor (IC50: 6.5 nM and 10 nM, respectively).Fórmula:C20H22N2Pureza:98%Forma y color:SolidPeso molecular:290.4JNJ 10191584 maleate
CAS:JNJ 10191584 maleate (VUF6002 maleate) is an orally active and selective antagonist of H4 receptor (Ki = 26 nM).Fórmula:C17H19ClN4O5Pureza:99.37%Forma y color:SolidPeso molecular:394.81Setastine
CAS:Setastine, a highly selective H1 receptor antagonist, acts as a non-sedative antihistamine.Fórmula:C22H28ClNOForma y color:SolidPeso molecular:357.92JNJ-28610244
CAS:JNJ-28610244 is a specific agonist of the H4 receptor. It acts by blocking Mac-1-dependent activation of p38 MAPK.Fórmula:C16H21N3OPureza:98%Forma y color:SolidPeso molecular:271.36GT 2016
CAS:GT 2016 is a H3 receptor antagonist.Fórmula:C19H31N3OPureza:98%Forma y color:SolidPeso molecular:317.47Bavisant dihydrochloride
CAS:Bavisant (JNJ-310010740) is an oral, selective H3 receptor antagonist enhancing wakefulness and cognition.Fórmula:C19H29Cl2N3O2Pureza:98%Forma y color:SolidPeso molecular:402.36VUF 8430 dihydrobromide
CAS:histamine H4 receptor full agonistFórmula:C4H12BrN5SPureza:98%Forma y color:SolidPeso molecular:242.14Seliforant
CAS:Seliforant is a histamine H4 receptor antagonist.Fórmula:C12H21N5Pureza:98%Forma y color:SolidPeso molecular:235.33Adriforant hydrochloride
CAS:<p>Adriforant hydrochloride is an antagonist of histamine H4 receptor.</p>Fórmula:C13H25Cl3N6Pureza:98%Forma y color:SolidPeso molecular:371.74UK-9040
CAS:UK-9040 inhibits gastric secretory.Fórmula:C23H31NSPureza:98%Forma y color:SolidPeso molecular:353.56VUF 8430
CAS:VUF 8430 is a selective agonist for the H4 receptor.Fórmula:C4H11N5SPureza:98%Forma y color:SolidPeso molecular:161.23VUF 5681 dihydrobromide
CAS:<p>histamine H3 receptor silent antagonist</p>Fórmula:C11H21Br2N3Pureza:98%Forma y color:SolidPeso molecular:355.11Thioperamide
CAS:histamine H3 and H4 antagonist/inverse agonistFórmula:C15H24N4SPureza:98%Forma y color:White SolidPeso molecular:292.44A331440
CAS:A331440 is an modulator of L-histidine and histamine H3 receptor.Fórmula:C22H27N3OForma y color:SolidPeso molecular:349.47MK-0249
CAS:<p>MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).</p>Fórmula:C23H24F3N3O2Pureza:99.90%Forma y color:SolidPeso molecular:431.45Loratadine N-oxide
CAS:Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine.Fórmula:C22H23ClN2O3Forma y color:SolidPeso molecular:398.88GSK 189254 HCl
CAS:GSK 189254A: histamine H3 antagonist, treats narcolepsy, may improve cognition and help with dementia, neuropathic pain.Fórmula:C21H26ClN3O2Pureza:98%Forma y color:SolidPeso molecular:387.9Repirinast
CAS:Repirinast is a mediator release inhibitor. It is used to treat asthma.Fórmula:C20H21NO5Forma y color:SolidPeso molecular:355.38Immepip
CAS:Immepip, a H3 agonist, has been shown to attenuate cortical histamine release and is utilized in the research of neurological diseases.Fórmula:C9H15N3Forma y color:SolidPeso molecular:165.24Phenyltoloxamine
CAS:Phenyltoloxamine (Bistrimin): antihistamine with sedative, analgesic properties, and Sigma-1 receptor affinity (Ki=160 nM).Fórmula:C17H21NOForma y color:SolidPeso molecular:255.35Mizolastine dihydrochloride
CAS:Mizolastine dihydrochloride is a histamine H1-receptor antagonist (IC50: 47 nM).Fórmula:C24H27Cl2FN6OPureza:98%Forma y color:SolidPeso molecular:505.42GSK334429
CAS:GSK334429 is an antagonist of histamine H3 receptor.Fórmula:C20H29F3N4OForma y color:SolidPeso molecular:398.47Sequifenadine
CAS:Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].Fórmula:C22H27NOForma y color:SolidPeso molecular:321.46A-940894
CAS:A-940894: Potent H4 receptor antagonist, anti-inflammatory, binds well to human/rat H4, low affinity for H1/H2/H3, good pharmacokinetics.Fórmula:C17H21N5Forma y color:SolidPeso molecular:295.38N-Acetylhistamine
CAS:N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine.Fórmula:C7H11N3OPureza:99.51%Forma y color:SolidPeso molecular:153.18Izuforant
CAS:Izuforant (JW1601) has anti-inflammatory effects, binds h5-HT3R (IC50: 9.1 μM), and blocks H4R orally (IC50: 36 nM).Fórmula:C12H12BrN7Forma y color:SolidPeso molecular:334.17A-943931
CAS:A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.Fórmula:C17H21N5Pureza:99.79%Forma y color:SolidPeso molecular:295.38Pitolisant oxalate
CAS:Pitolisant oxalate is a potent and selective inverse agonist of nonimidazole at the recombinant human histamine H3 receptor with Ki of 0.16 nM.Fórmula:C19H28ClNO5Pureza:98%Forma y color:SolidPeso molecular:385.88Pirolate
CAS:Pirolate is a receptor of histamine H1.Fórmula:C16H15N3O5Pureza:98%Forma y color:SolidPeso molecular:329.31Bepotastine tosylate
CAS:Bepotastine tosylate: Oral 2nd-gen H1 antagonist, inhibits histamine effects on NGF; treats conjunctivitis, urticaria.Fórmula:C28H33ClN2O6SForma y color:SolidPeso molecular:561.09VUF-10497
CAS:VUF-10497: H4 receptor inverse agonist, anti-inflammatory in rats, binds human H1 receptor (pKi=7.57).Fórmula:C18H20ClN5SPureza:98%Forma y color:SolidPeso molecular:373.9Phenindamine
CAS:Phenindamine (Nu 1504) is an H1-receptor antagonist which is antihistamine[1].Fórmula:C19H19NForma y color:SolidPeso molecular:261.36Acreozast
CAS:Acreozast, a histamine release inhibitor, is used potentially for the treatment of asthma and atopic dermatitis.Fórmula:C15H14ClN3O6Forma y color:SolidPeso molecular:367.74CP19
CAS:CP19 blocks histamine receptors; inhibits EBOV and MARV with IC50s of 3.4 μM and 29.5 μM, respectively; antiviral [1].Fórmula:C26H30N2O5Forma y color:SolidPeso molecular:450.53Phenindamine Tartrate
CAS:Phenindamine Tartrate, an antihistamine and anticholinergic, treats colds and allergies like sneezing and rashes.Fórmula:C23H25NO6Forma y color:SolidPeso molecular:411.454INCB38579
CAS:INCB38579: Oral, selective H4 antagonist; crosses brain barrier; IC50s - hH4R: 4.8 nM, mH4R: 42 nM, rH4R: 32 nM; anti-inflammatory and antipruritic.Fórmula:C25H34N6OForma y color:SolidPeso molecular:434.58Nebidrazine
CAS:Nebidrazine is an alpha-adrenoceptor agonist.Fórmula:C9H8Cl2N6Forma y color:SolidPeso molecular:271.11Toreforant
CAS:Toreforant is an effective and selective histamine H4 receptor antagonist (Ki at the human receptor: 8.4 nM).Fórmula:C23H32N6Pureza:98%Forma y color:SolidPeso molecular:392.54SUN 1334H
CAS:SUN 1334H is a potent, orally active, highly selective antagonist of H1 receptor(Ki of 9.7 nM).Fórmula:C23H28Cl2F2N2O3Pureza:98%Forma y color:SolidPeso molecular:489.38(R)-(-)-α-Methylhistamine dihydrobromide
CAS:(R)-(-)-α-Methylhistamine dihydrobromide is a potent and selective agonist of H3 histamine receptor( Kd of 50.3 nM).Fórmula:C6H13Br2N3Pureza:98%Forma y color:SolidPeso molecular:287ICI 162,846
CAS:ICI 162,846 is an orally active and potent H2 receptor antagonist that inhibits gastric secretion and may be used in the study of duodenal ulcers.Fórmula:C11H17F3N6OPureza:97.45%Forma y color:SolidPeso molecular:306.29Iodophenpropit dihydrobromide
CAS:Iodophenpropit dihydrobromide: selective histamine H3 antagonist, reversible binding, high affinity (KD: 0.32 nM).Fórmula:C15H20BrIN4SPureza:98%Forma y color:SolidPeso molecular:495.22PF-03654746 Tosylate
CAS:<p>PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration.</p>Fórmula:C25H32F2N2O4SPureza:98%Forma y color:SolidPeso molecular:494.6Hetramine
CAS:Hetramine is a synthetic pyrimidine agent that possesses antihistamine and anti anaphylactic effects.Fórmula:C15H20N4Pureza:98%Forma y color:SolidPeso molecular:256.35Fenethazine
CAS:Fenethazine is an effective antihistamine used as an antiallergic drug.Fórmula:C16H18N2SForma y color:SolidPeso molecular:270.39HSR-609
CAS:HSR-609, a histamine H1 receptor antagonist, is used potentially for the treatment of allergic rhinitis.Fórmula:C21H21FN2O3Pureza:98%Forma y color:SolidPeso molecular:368.4BMH-7
CAS:BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.Fórmula:C20H21N5OPureza:99.71%Forma y color:SolidPeso molecular:347.41Tei 6472
CAS:Tei 6472 is a more hydrophilic form of TEI-1338 which is a novel, selective lipoxygenase inhibitor.Fórmula:C32H39N3O5Pureza:98%Forma y color:SolidPeso molecular:545.67Nα-Methylhistamine dihydrochloride
CAS:Nα-Methylhistamine dihydrochloride is a histamine H3 receptor agonist.Fórmula:C6H13Cl2N3Pureza:98%Forma y color:SolidPeso molecular:198.094Amthamine dihydrobromide
CAS:H2 agonistFórmula:C6H13Br2N3SPureza:98%Forma y color:SolidPeso molecular:319.06Carcainium chloride
CAS:Carcainium chloride (Carcainium (chloride)) is a derivative of Lidocaine and possesses an antitussive effect.Fórmula:C18H22ClN3O2Pureza:99.89%Forma y color:SolidPeso molecular:347.84DA 4643
CAS:DA 4643, a histamine H2-receptor antagonist, binds similarly to mifentidine at the receptor.Fórmula:C12H16Cl2N6SPureza:98%Forma y color:SolidPeso molecular:347.26Mequitamium iodide
CAS:Mequitamium iodide is a PAF inhibitor, curbing platelet aggregation and bronchoconstriction without blocking PAF receptors.Fórmula:C21H25IN2SForma y color:SolidPeso molecular:464.41Impentamine dihydrobromide
CAS:Impentamine dihydrobromide is a histamine H3 receptor antagonist.Fórmula:C8H17Br2N3Pureza:98%Forma y color:SolidPeso molecular:315.05Chloracyzine
CAS:Chloracyzine lowers heart oxygen use, shrinks coronary flow after brief dilation, slightly ups heart rate and arterial pressure.Fórmula:C19H21ClN2OSForma y color:SolidPeso molecular:360.9AHR-13268D
CAS:AHR-13268D is a new agent of antiallergic/antihistaminic.Fórmula:C28H29F2NNaO4Pureza:98%Forma y color:SolidPeso molecular:504.53AHR-14310C
CAS:AHR-14310C is a long-acting and nonsedating H1-antihistamine.Fórmula:C24H28F2N2O3Pureza:98%Forma y color:SolidPeso molecular:430.49NNC-38-1049
CAS:NNC-38-1049 is a novel selective antagonist of histamine H3.Fórmula:C19H25ClN2O2Pureza:98%Forma y color:SolidPeso molecular:348.87Aplysamine-1
CAS:Aplysamine-1 is an antagonist of histamine H3 receptor.Fórmula:C15H24Br2N2OPureza:98%Forma y color:SolidPeso molecular:408.17Embramine
CAS:Embramine, used as an antihistamine and anticholinergic, is a monoethanolamine.Fórmula:C18H22BrNOPureza:98%Forma y color:SolidPeso molecular:348.28Linadryl hydrochloride
CAS:<p>Linadryl hydrochloride may have antihistamine activity.</p>Fórmula:C19H24ClNO2Forma y color:SolidPeso molecular:333.85Ramixotidine
CAS:Ramixotidine is a competitive antagonist of histamine H2-receptor.Fórmula:C16H21N3O3SPureza:98%Forma y color:SolidPeso molecular:335.42Dacemazine hydrochloride
CAS:Dacemazine is a phenothiazine derivative that acts as a histamine antagonist at the H1 subtype. It was also assessed as a possible anticancer drug.Fórmula:C16H17ClN2OSPureza:98%Forma y color:SolidPeso molecular:320.84Rocastine
CAS:<p>Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.</p>Fórmula:C13H19N3OSPureza:98.26%Forma y color:SolidPeso molecular:265.37H3 receptor-MO-1
CAS:H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders.Fórmula:C20H27N3O2Pureza:99.11%Forma y color:SolidPeso molecular:341.45Bamirastine
CAS:Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect onFórmula:C31H37N5O3Pureza:96.68%Forma y color:SolidPeso molecular:527.66CP-66948
CAS:CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa.Fórmula:C13H20N6SPureza:99.14%Forma y color:SolidPeso molecular:292.4PF-03654764
CAS:<p>PF-03654764, an oral H3 receptor blocker, Ki: human 1.2 nM, rat 7.9 nM, used with Fexofenadine for allergic rhinitis.</p>Fórmula:C20H28F2N2OPureza:>99.99%Forma y color:SolidPeso molecular:350.45Lavoltidine
CAS:Lavoltidine (Loxtidine) is potent and selective H2 receptor antagonist, oral and irreversible,inhibits gastric acid secretion, gastroesophageal reflux disease.Fórmula:C19H29N5O2Pureza:98.30% - 98.36%Forma y color:SolidPeso molecular:359.47Propiomazine HCl
CAS:Propiomazine HCl is an analgesia adjunct.Fórmula:C20H25ClN2OSForma y color:SolidPeso molecular:376.94VUF14862
CAS:VUF14862 is a robust and fatigue-resistant photoswitchable GPCR antagonist.Fórmula:C26H32N4O2Forma y color:SolidPeso molecular:432.56Sch 44643
CAS:Sch 44643 is an antagonist of platelet activating factor with oral activity.Fórmula:C25H22ClN3O2Forma y color:SolidPeso molecular:431.91Brl 22321
CAS:Brl 22321 is a mast cell stabilizer.Fórmula:C12H9N3O2Forma y color:SolidPeso molecular:227.22BL 6341A
CAS:BL 6341A is related to Tumor data and H2-antagonists or anti-histaminsFórmula:C9H14N8OS3Forma y color:SolidPeso molecular:346.46(R)-Azelastine
CAS:(R)-Azelastine, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.Fórmula:C22H24ClN3OForma y color:SolidPeso molecular:381.9Aceprometazine
CAS:Aceprometazine (1664CB) is an antipsychotic which is orally active. Aceprometazine can be used in psychiatric disorders research, for example, depression [1].Fórmula:C19H22N2OSForma y color:SolidPeso molecular:326.46Noberastine maleate
CAS:Noberastine maleate, a fast-acting furan-derived H1 antagonist, peaks at 4 hours with minimal CNS effects and maximal efficacy at 30 mg/day.Fórmula:C25H29N5O9Forma y color:SolidPeso molecular:543.53ROS 234 dioxalate
CAS:ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor)Fórmula:C17H19N5O8Pureza:98%Forma y color:SolidPeso molecular:421.37Fenspiride-d5
CAS:Fenspiride-d5: internal standard for GC/LC-MS quantification, H1 antagonist, NSAID, anti-inflammatory, selective PDE4,5,3 inhibitor.Fórmula:C15H15D5N2O2Forma y color:SolidPeso molecular:265.36Dacemazine
CAS:Dacemazine is used to treat depression.Fórmula:C16H16N2OSForma y color:SolidPeso molecular:284.38VUF14738
CAS:VUF14738 is a robust and fatigue-resistant photoswitchable GPCR antagonist.Fórmula:C25H32N4O2Forma y color:SolidPeso molecular:420.55ReN-1869 hydrochloride
CAS:ReN 1869 hydrochloride is a novel, selective antagonist of histamine H1 receptor.Fórmula:C24H28ClNO2Pureza:98%Forma y color:SolidPeso molecular:397.94Azelastine
CAS:<p>Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.</p>Fórmula:C22H24ClN3OPureza:99.35%Forma y color:White Crystal PowderPeso molecular:381.90BMY-25271
CAS:BMY-25271 is an antagonist of histamine H2 receptor.Fórmula:C12H19N5O2S2Pureza:98%Forma y color:SolidPeso molecular:329.44Mianserin
CAS:Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family.Fórmula:C18H20N2Pureza:99.85%Forma y color:SolidPeso molecular:264.36Wy 49051
CAS:Wy 49051 is an orally active antagonist of H1 receptor(IC50 of 44 nM).Fórmula:C28H33N5O3Pureza:99.89%Forma y color:SolidPeso molecular:487.59Niperotidine
CAS:Niperotidine is an antagonist of histamine H2-receptor.Fórmula:C20H26N4O5SPureza:98%Forma y color:SolidPeso molecular:434.51Vapitadine dihydrochloride
CAS:Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.Fórmula:C17H22Cl2N4OPureza:98.28% - 99.30%Forma y color:SolidPeso molecular:369.29GSK-239512
CAS:GSK-239512 is an antagonist of H3 receptor and can be used in studies about the treatment of cognitive dysfunction in neurodegenerative disorders.Fórmula:C23H27N3O2Pureza:99.62% - 99.74%Forma y color:SolidPeso molecular:377.48H4R antagonist 1
CAS:H4R antagonist 1: selective histamine H4R inhibitor, IC50 27 nM, no affinity for H1R, H2R, H3R.Fórmula:C11H11BrN8Forma y color:SolidPeso molecular:335.16(±)-Tazifylline
CAS:(±)-Tazifylline is a selective and long-acting antagonist of histamine H1 receptor.Fórmula:C23H32N6O3SPureza:99.54%Forma y color:SolidPeso molecular:472.6PF 03654746 FA
PF 03654746 FA is a human histamine receptor H(3) antagonist that can be used to study cognitive impairment and Alzheimer's disease.Fórmula:C19H26F2N2O3Pureza:99.44%Forma y color:SoildPeso molecular:368.42JNJ-39220675
CAS:JNJ-39220675, a selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.Fórmula:C21H24FN3O2Pureza:98.13% - 99.89%Forma y color:SolidPeso molecular:369.43Antihistamine-1
CAS:Antihistamine-1 是能够渗透血脑屏障的 H1-抗组胺药 (Ki=6.9 nM), 它也是 CYP2D6 和 hERG 通道的抑制剂，其 IC50 值分别为 5.4 和 0.8 μM。Fórmula:C23H24FN5Pureza:99.69%Forma y color:SolidPeso molecular:389.47DF-1111301
CAS:<p>DF-1111301 is a novel anti-allergic compound with anti-histamine H1 and anti-PAF activity.</p>Fórmula:C15H25Cl2N3OPureza:99.17%Forma y color:SolidPeso molecular:334.29Abt-288
CAS:ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.Fórmula:C23H24N4OPureza:98.17% - 98.49%Forma y color:SolidPeso molecular:372.46Enerisant hydrochloride
CAS:<p>Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteins</p>Fórmula:C22H31ClN4O3Pureza:99.95%Forma y color:SolidPeso molecular:434.96KSK68
CAS:<p>KSK68 is a sigma-1 and histamine H3 receptor antagonist with analgesic activity, inhibits H3 receptors and can be used to study pain.</p>Fórmula:C23H28N2O2Pureza:99.11%Forma y color:SolidPeso molecular:364.48Proxyfan
CAS:Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.Fórmula:C13H16N2OPureza:99.68%Forma y color:SolidPeso molecular:216.28KSK94
CAS:KSK94 is an H3 receptor antagonist that inhibits sigma-2 receptors , with a Ki value of 75.2 nM, and can be used to study injurious pain.Fórmula:C25H26N4OPureza:99.60%Forma y color:SolidPeso molecular:398.5Impromidine hydrochloride
CAS:<p>Impromidine hydrochloride is a very potent and specific histamine H2 receptor agonist for conducting cardiovascular studies.</p>Fórmula:C14H26Cl3N7SPureza:99.82%Forma y color:SolidPeso molecular:430.83ReN-1869
CAS:ReN-1869 is a novel selective histamine H(1) receptor antagonist with anti-neurogenic pain and anti-inflammatory activity for the study of neurological diseasesFórmula:C24H27NO2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:361.48Pitolisant
CAS:Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.Fórmula:C17H26ClNOPureza:99.84%Forma y color:SolidPeso molecular:295.85NP10679
CAS:NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.Fórmula:C23H26F3N3O3Pureza:99.43%Forma y color:SolidPeso molecular:449.47D18024
CAS:<p>D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.</p>Fórmula:C29H31ClFN3OPureza:99.86%Forma y color:SolidPeso molecular:492.03Irdabisant
CAS:Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.Fórmula:C18H23N3O2Pureza:99.96%Forma y color:SolidPeso molecular:313.39Noberastine
CAS:Noberastine (R 64947) is a novel histamine H1 antagonist with potent and specific peripheral antihistamine activity.Fórmula:C17H21N5OPureza:99.72% - >99.99%Forma y color:SolidPeso molecular:311.38Efletirizine
CAS:<p>Efletirizine (UCB-28754), a histamine blocker and 5-LO inhibitor, aids in topical allergy treatment.</p>Fórmula:C21H24F2N2O3Pureza:99.39%Forma y color:SolidPeso molecular:390.42Bavisant
CAS:Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist.Fórmula:C19H27N3O2Pureza:99.21% - 99.65%Forma y color:SolidPeso molecular:329.44JZP-361
CAS:JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.Fórmula:C22H20ClN5OPureza:99.82%Forma y color:SolidPeso molecular:405.88Eclazolast
CAS:<p>Eclazolast (RHC 2871), a lipophilic anti-allergic, inhibits mast cell mediator release by affecting Fc(epsilon)RI-related processes, dose-dependently.</p>Fórmula:C12H12ClNO4Pureza:98.36% - 98.58%Forma y color:SolidPeso molecular:269.68Clemastine
CAS:Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects.Fórmula:C21H26ClNOPureza:99.21%Forma y color:SolidPeso molecular:343.89KP136
CAS:<p>KP136 is an orally effective antiallergic compound (IC50: 76.1 μg/mL for histamine release and 63 ug/mL for degranulation).</p>Fórmula:C16H18N4O3Pureza:98.3% - 98.61%Forma y color:SolidPeso molecular:314.34Linetastine
CAS:Linetastine (TMK-688) inhibits 5-LOX, blocks leukotrienes, counters histamine; researched for asthma, atherosclerosis, ulcers.Fórmula:C35H40N2O6Pureza:99.76%Forma y color:SolidPeso molecular:584.7Immethridine dihydrobromide
CAS:<p>Immethridine dihydrobromide is a histamine H3 receptor agonist.</p>Fórmula:C9H11Br2N3Pureza:97.61% - 98.14%Forma y color:SolidPeso molecular:321.01APD-916
CAS:APD-916, an H3 receptor antagonist, exhibits favorable pharmacokinetic properties. Oral administration of APD-916 has been demonstrated to enhance wakefulness in various animal models.Fórmula:C23H31NO3SForma y color:SolidPeso molecular:401.56Minocromil
CAS:Minocromil is a new agent of Anti-asthmatic.Fórmula:C18H16N2O6Pureza:98%Forma y color:SolidPeso molecular:356.33JNJ-28583867
CAS:JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.Fórmula:C24H32N2O2SForma y color:SolidPeso molecular:412.59GSK-1004723
CAS:GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.Fórmula:C39H49ClN4O2Forma y color:SolidPeso molecular:641.28Cipralisant maleate
CAS:Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.Fórmula:C18H24N2O4Forma y color:SolidPeso molecular:332.39Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Fórmula:C26H29FN2O2Forma y color:SolidPeso molecular:420.52UCB-35440
CAS:UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.Fórmula:C31H34ClN5O4Forma y color:SolidPeso molecular:576.09Cipralisant
CAS:Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.Fórmula:C14H20N2Pureza:98%Forma y color:SolidPeso molecular:216.32CI-949
CAS:<p>CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).</p>Fórmula:C20H20N6O3Pureza:98%Forma y color:SolidPeso molecular:392.41GT-2331
CAS:<p>GT-2331 is a histamine H3 receptor antagonist.</p>Fórmula:C14H20N2Forma y color:SolidPeso molecular:216.32Levocabastine hydrochloride
CAS:<p>Levocabastine HCl is an agent with antihistaminic activity.</p>Fórmula:C26H30ClFN2O2Forma y color:SolidPeso molecular:456.98Quinotolast sodium
CAS:<p>Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.</p>Fórmula:C17H12N6NaO3Pureza:98%Forma y color:SolidPeso molecular:371.312A-349821
CAS:<p>A-349821 is an H3 receptor agonist radioligand.</p>Fórmula:C28H35F3N2O5Forma y color:SolidPeso molecular:536.59Ebrotidine
CAS:Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.Fórmula:C14H17BrN6O2S3Pureza:97.519%Forma y color:SolidPeso molecular:477.42H3 receptor antagonist 1
CAS:H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.Fórmula:C20H28F2N2OPureza:98%Forma y color:SolidPeso molecular:350.45H4R antagonist 2
CAS:H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoidFórmula:C13H17N5OPureza:98%Forma y color:SolidPeso molecular:259.31Hydroxydione
CAS:Hydroxydione, a neuroactive steroid with general anesthetic properties, is utilized in anesthesia-related research [1] [2].Fórmula:C21H32O3Forma y color:SolidPeso molecular:332.48Embramine hydrochloride
CAS:Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].Fórmula:C18H23BrClNOForma y color:SolidPeso molecular:384.74ST-1006
CAS:<p>ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.</p>Fórmula:C16H20Cl2N6Pureza:98.87% - 99.96%Forma y color:SolidPeso molecular:367.28Enerisant
CAS:Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.Fórmula:C22H30N4O3Pureza:99.7%Forma y color:SoildPeso molecular:398.50ONO-8809
CAS:ONO-8809: Thromboxane A2 antagonist, reduces airway hyperresponse, macrophage accumulation, and MMP-9 in SHRSP brains.Fórmula:C30H46BrNO4SPureza:98%Forma y color:SolidPeso molecular:596.66H3R antagonist 1
CAS:H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).Fórmula:C19H23N3O3Forma y color:SolidPeso molecular:341.4Histamine H3 antagonist-1
CAS:<p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>Fórmula:C24H28F3N3O2Forma y color:SolidPeso molecular:447.49Tixanox sodium
CAS:Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.Fórmula:C15H9NaO5SForma y color:SolidPeso molecular:324.28Sitamaquine hydrochloride
CAS:Sitamaquine hydrochloride (WR 6026) is an orally active 8-aminoquinoline analog with antileishmanial activity. This compound inhibits mitochondrial complex II (succinate dehydrogenase) and is characterized by its lipophilic weak base properties. It rapidly accumulates in the acidic compartments of Leishmania parasites, predominantly localizing within the acidocalcisomes.Fórmula:C21H35Cl2N3OForma y color:SolidPeso molecular:416.43Arpromidine
CAS:<p>Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.</p>Fórmula:C21H25FN6Forma y color:SolidPeso molecular:380.462CI-624
CAS:CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.Fórmula:C8H8N2SForma y color:SolidPeso molecular:164.228Nedocromil sodium
CAS:Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.Fórmula:C19H17NNaO7Pureza:98%Forma y color:SolidPeso molecular:394.335H3R antagonist 5
CAS:<p>H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.</p>Fórmula:C23H32N2O4Forma y color:SolidPeso molecular:400.511H1R ligand-1
CAS:<p>H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.</p>Fórmula:C19H23NOForma y color:SolidPeso molecular:281.392(R)-(-)-α-Methylhistamine dihydrochloride
CAS:<p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>Fórmula:C6H13Cl2N3Forma y color:SolidPeso molecular:198.09Imetit dihydrobromide
CAS:Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Fórmula:C6H12Br2N4SPureza:98%Forma y color:SolidPeso molecular:332.06
