Receptor de histamina
Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.
Se han encontrado 381 productos de "Receptor de histamina"
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Minocromil
CAS:Minocromil is a new agent of Anti-asthmatic.Fórmula:C18H16N2O6Pureza:98%Forma y color:SolidPeso molecular:356.33JNJ-28583867
CAS:JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.Fórmula:C24H32N2O2SForma y color:SolidPeso molecular:412.59GSK-1004723
CAS:GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.Fórmula:C39H49ClN4O2Forma y color:SolidPeso molecular:641.28Cipralisant maleate
CAS:Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.Fórmula:C18H24N2O4Forma y color:SolidPeso molecular:332.39Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Fórmula:C26H29FN2O2Forma y color:SolidPeso molecular:420.52UCB-35440
CAS:UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.Fórmula:C31H34ClN5O4Forma y color:SolidPeso molecular:576.09Cipralisant
CAS:Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.Fórmula:C14H20N2Pureza:98%Forma y color:SolidPeso molecular:216.32CI-949
CAS:<p>CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).</p>Fórmula:C20H20N6O3Pureza:98%Forma y color:SolidPeso molecular:392.41GT-2331
CAS:<p>GT-2331 is a histamine H3 receptor antagonist.</p>Fórmula:C14H20N2Forma y color:SolidPeso molecular:216.32Levocabastine hydrochloride
CAS:<p>Levocabastine HCl is an agent with antihistaminic activity.</p>Fórmula:C26H30ClFN2O2Forma y color:SolidPeso molecular:456.98Quinotolast sodium
CAS:<p>Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.</p>Fórmula:C17H12N6NaO3Pureza:98%Forma y color:SolidPeso molecular:371.312A-349821
CAS:<p>A-349821 is an H3 receptor agonist radioligand.</p>Fórmula:C28H35F3N2O5Forma y color:SolidPeso molecular:536.59Ebrotidine
CAS:Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.Fórmula:C14H17BrN6O2S3Pureza:97.519%Forma y color:SolidPeso molecular:477.42H3 receptor antagonist 1
CAS:H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.Fórmula:C20H28F2N2OPureza:98%Forma y color:SolidPeso molecular:350.45H4R antagonist 2
CAS:H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoidFórmula:C13H17N5OPureza:98%Forma y color:SolidPeso molecular:259.31Hydroxydione
CAS:Hydroxydione, a neuroactive steroid with general anesthetic properties, is utilized in anesthesia-related research [1] [2].Fórmula:C21H32O3Forma y color:SolidPeso molecular:332.48Embramine hydrochloride
CAS:Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].Fórmula:C18H23BrClNOForma y color:SolidPeso molecular:384.74ST-1006
CAS:<p>ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.</p>Fórmula:C16H20Cl2N6Pureza:98.87% - 99.96%Forma y color:SolidPeso molecular:367.28Enerisant
CAS:Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.Fórmula:C22H30N4O3Pureza:99.7%Forma y color:SoildPeso molecular:398.50ONO-8809
CAS:ONO-8809: Thromboxane A2 antagonist, reduces airway hyperresponse, macrophage accumulation, and MMP-9 in SHRSP brains.Fórmula:C30H46BrNO4SPureza:98%Forma y color:SolidPeso molecular:596.66H3R antagonist 1
CAS:H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).Fórmula:C19H23N3O3Forma y color:SolidPeso molecular:341.4Histamine H3 antagonist-1
CAS:<p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>Fórmula:C24H28F3N3O2Forma y color:SolidPeso molecular:447.49Tixanox sodium
CAS:Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.Fórmula:C15H9NaO5SForma y color:SolidPeso molecular:324.28Sitamaquine hydrochloride
CAS:Sitamaquine hydrochloride (WR 6026) is an orally active 8-aminoquinoline analog with antileishmanial activity. This compound inhibits mitochondrial complex II (succinate dehydrogenase) and is characterized by its lipophilic weak base properties. It rapidly accumulates in the acidic compartments of Leishmania parasites, predominantly localizing within the acidocalcisomes.Fórmula:C21H35Cl2N3OForma y color:SolidPeso molecular:416.43Arpromidine
CAS:<p>Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.</p>Fórmula:C21H25FN6Forma y color:SolidPeso molecular:380.462CI-624
CAS:CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.Fórmula:C8H8N2SForma y color:SolidPeso molecular:164.228Nedocromil sodium
CAS:Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.Fórmula:C19H17NNaO7Pureza:98%Forma y color:SolidPeso molecular:394.335H3R antagonist 5
CAS:<p>H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.</p>Fórmula:C23H32N2O4Forma y color:SolidPeso molecular:400.511H1R ligand-1
CAS:<p>H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.</p>Fórmula:C19H23NOForma y color:SolidPeso molecular:281.392(R)-(-)-α-Methylhistamine dihydrochloride
CAS:<p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>Fórmula:C6H13Cl2N3Forma y color:SolidPeso molecular:198.09Imetit dihydrobromide
CAS:Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Fórmula:C6H12Br2N4SPureza:98%Forma y color:SolidPeso molecular:332.06
