Receptor de histamina
Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.
Se han encontrado 358 productos de "Receptor de histamina"
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Niperotidine
CAS:<p>Niperotidine is an antagonist of histamine H2-receptor.</p>Fórmula:C20H26N4O5SPureza:98%Forma y color:SolidPeso molecular:434.51Iodophenpropit dihydrobromide
CAS:<p>Iodophenpropit dihydrobromide: selective histamine H3 antagonist, reversible binding, high affinity (KD: 0.32 nM).</p>Fórmula:C15H20BrIN4SPureza:98%Forma y color:SolidPeso molecular:495.22PF-03654746 Tosylate
CAS:<p>PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration.</p>Fórmula:C25H32F2N2O4SPureza:98%Forma y color:SolidPeso molecular:494.6JNJ-39220675
CAS:<p>JNJ-39220675, a selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.</p>Fórmula:C21H24FN3O2Pureza:98.13% - 99.89%Forma y color:SolidPeso molecular:369.43JNJ-28610244
CAS:<p>JNJ-28610244 is a specific agonist of the H4 receptor. It acts by blocking Mac-1-dependent activation of p38 MAPK.</p>Fórmula:C16H21N3OPureza:98%Forma y color:SolidPeso molecular:271.36Hetramine
CAS:<p>Hetramine is a synthetic pyrimidine agent that possesses antihistamine and anti anaphylactic effects.</p>Fórmula:C15H20N4Pureza:98%Forma y color:SolidPeso molecular:256.35Fenethazine
CAS:<p>Fenethazine is an effective antihistamine used as an antiallergic drug.</p>Fórmula:C16H18N2SForma y color:SolidPeso molecular:270.39HSR-609
CAS:<p>HSR-609, a histamine H1 receptor antagonist, is used potentially for the treatment of allergic rhinitis.</p>Fórmula:C21H21FN2O3Pureza:98%Forma y color:SolidPeso molecular:368.4Setastine
CAS:<p>Setastine, a highly selective H1 receptor antagonist, acts as a non-sedative antihistamine.</p>Fórmula:C22H28ClNOForma y color:SolidPeso molecular:357.92BMH-7
CAS:<p>BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.</p>Fórmula:C20H21N5OPureza:99.71%Forma y color:SolidPeso molecular:347.41Tei 6472
CAS:<p>Tei 6472 is a more hydrophilic form of TEI-1338 which is a novel, selective lipoxygenase inhibitor.</p>Fórmula:C32H39N3O5Pureza:98%Forma y color:SolidPeso molecular:545.67Nα-Methylhistamine dihydrochloride
CAS:<p>Nα-Methylhistamine dihydrochloride is a histamine H3 receptor agonist.</p>Fórmula:C6H13Cl2N3Pureza:98%Forma y color:SolidPeso molecular:198.094Embramine
CAS:<p>Embramine, used as an antihistamine and anticholinergic, is a monoethanolamine.</p>Fórmula:C18H22BrNOPureza:98%Forma y color:SolidPeso molecular:348.28PF 03654746 FA
<p>PF 03654746 FA is a human histamine receptor H(3) antagonist that can be used to study cognitive impairment and Alzheimer's disease.</p>Fórmula:C19H26F2N2O3Pureza:99.44%Forma y color:SoildPeso molecular:368.42VUF 8430 dihydrobromide
CAS:<p>histamine H4 receptor full agonist</p>Fórmula:C4H12BrN5SPureza:98%Forma y color:SolidPeso molecular:242.14Bavisant dihydrochloride
CAS:<p>Bavisant (JNJ-310010740) is an oral, selective H3 receptor antagonist enhancing wakefulness and cognition.</p>Fórmula:C19H29Cl2N3O2Pureza:98%Forma y color:SolidPeso molecular:402.36ICI 162,846
CAS:<p>ICI 162,846 is an orally active and potent H2 receptor antagonist that inhibits gastric secretion and may be used in the study of duodenal ulcers.</p>Fórmula:C11H17F3N6OPureza:97.45%Forma y color:SolidPeso molecular:306.29Setastine HCl
CAS:<p>Setastine HCl is a potent antagonist of histamine H1-receptor mediated responses.</p>Fórmula:C22H29Cl2NOForma y color:SolidPeso molecular:394.38A 987306
CAS:<p>A-987306: Potent, oral histamine H4 antagonist; Ki: 3.4 nM (rat), 5.8 nM (human); reduces inflammation in mouse peritonitis.</p>Fórmula:C18H25N5OForma y color:SolidPeso molecular:327.42Azelastine
CAS:<p>Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.</p>Fórmula:C22H24ClN3OPureza:99.35%Forma y color:White Crystal PowderPeso molecular:381.90Zaltidine
CAS:<p>Zaltidine is an antagonist of H2-receptor, and has the antisecretory action.</p>Fórmula:C8H10N6SPureza:98%Forma y color:SolidPeso molecular:222.27JNJ-10191584
CAS:<p>JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammation</p>Fórmula:C13H15ClN4OForma y color:SolidPeso molecular:278.74Alimemazine
CAS:<p>Alimemazine, an antipruritic and HA-receptor antagonist, also partially activates H1R and other GPCRs.</p>Fórmula:C18H22N2SPureza:98%Forma y color:Crystals SolidPeso molecular:298.45Aminopotentidine
CAS:<p>H2 antagonist</p>Fórmula:C26H35N7O2Pureza:98%Forma y color:SolidPeso molecular:477.6Zolantidine dimaleate
CAS:<p>H2 receptor antagonist</p>Fórmula:C26H31N3O5SPureza:98%Forma y color:SolidPeso molecular:497.61BMY-25271
CAS:<p>BMY-25271 is an antagonist of histamine H2 receptor.</p>Fórmula:C12H19N5O2S2Pureza:98%Forma y color:SolidPeso molecular:329.44ABT-239
CAS:<p>ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.</p>Fórmula:C22H22N2OPureza:>99.99%Forma y color:SolidPeso molecular:330.42(R)-Mequitazine
CAS:<p>(R)-Mequitazine, a muscarinic acetylcholine receptor (M-AChRs) antagonist, is used potentially for the treatment of asthma.</p>Fórmula:C20H22N2SForma y color:SolidPeso molecular:322.47A-304121
CAS:<p>A-304121 is a histamine H(3) receptor.</p>Fórmula:C20H29N3O3Forma y color:SolidPeso molecular:359.46OUP-186
CAS:<p>OUP-186 is a selective H3 receptor antagonist that suppresses breast cancer cell growth with an IC50 of ~50 μM and induces apoptosis.</p>Fórmula:C19H30ClN3SForma y color:SolidPeso molecular:367.98JNJ 10181457 dihydrochloride
CAS:<p>JNJ 10181457 dihydrochloride is a Histamine H3 receptor antagonist.</p>Fórmula:C20H28N2OPureza:98%Forma y color:SolidPeso molecular:312.45Mianserin
CAS:<p>Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family.</p>Fórmula:C18H20N2Pureza:99.85%Forma y color:SolidPeso molecular:264.36Wy 49051
CAS:<p>Wy 49051 is an orally active antagonist of H1 receptor(IC50 of 44 nM).</p>Fórmula:C28H33N5O3Pureza:99.89%Forma y color:SolidPeso molecular:487.59ROS 234
CAS:<p>ROS 234 is a potent H3 antagonist with pKB 9.46 for Guinea-pig ileum and pKi 8.90 for Rat cortex; ED50 of 19.12 mg/kg in rats, but with limited central access.</p>Fórmula:C13H15N5Forma y color:SolidPeso molecular:241.29PF-03654746
CAS:<p>PF-03654746: selective H3 antagonist, boosts cognition in Alzheimer's, may treat allergic rhinitis.</p>Fórmula:C18H24F2N2OPureza:98.85% - 99.57%Forma y color:SolidPeso molecular:322.39AZD5213
CAS:<p>AZD5213: selective human H3 receptor antagonist, pKi 9.3, for sleep/cognition research.</p>Fórmula:C19H25N3O2Forma y color:SolidPeso molecular:327.42Repirinast
CAS:<p>Repirinast is a mediator release inhibitor. It is used to treat asthma.</p>Fórmula:C20H21NO5Forma y color:SolidPeso molecular:355.38Immepip
CAS:<p>Immepip, a H3 agonist, has been shown to attenuate cortical histamine release and is utilized in the research of neurological diseases.</p>Fórmula:C9H15N3Forma y color:SolidPeso molecular:165.24Phenyltoloxamine
CAS:<p>Phenyltoloxamine (Bistrimin): antihistamine with sedative, analgesic properties, and Sigma-1 receptor affinity (Ki=160 nM).</p>Fórmula:C17H21NOForma y color:SolidPeso molecular:255.35Mizolastine dihydrochloride
CAS:<p>Mizolastine dihydrochloride is a histamine H1-receptor antagonist (IC50: 47 nM).</p>Fórmula:C24H27Cl2FN6OPureza:98%Forma y color:SolidPeso molecular:505.42GSK 189254 HCl
CAS:<p>GSK 189254A: histamine H3 antagonist, treats narcolepsy, may improve cognition and help with dementia, neuropathic pain.</p>Fórmula:C21H26ClN3O2Pureza:98%Forma y color:SolidPeso molecular:387.9GSK334429
CAS:<p>GSK334429 is an antagonist of histamine H3 receptor.</p>Fórmula:C20H29F3N4OForma y color:SolidPeso molecular:398.47Sequifenadine
CAS:<p>Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].</p>Fórmula:C22H27NOForma y color:SolidPeso molecular:321.46A-940894
CAS:<p>A-940894: Potent H4 receptor antagonist, anti-inflammatory, binds well to human/rat H4, low affinity for H1/H2/H3, good pharmacokinetics.</p>Fórmula:C17H21N5Forma y color:SolidPeso molecular:295.38Loratadine N-oxide
CAS:<p>Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine.</p>Fórmula:C22H23ClN2O3Forma y color:SolidPeso molecular:398.88MK-0249
CAS:<p>MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).</p>Fórmula:C23H24F3N3O2Pureza:99.90%Forma y color:SolidPeso molecular:431.45N-Acetylhistamine
CAS:<p>N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine.</p>Fórmula:C7H11N3OPureza:99.51%Forma y color:SolidPeso molecular:153.18Izuforant
CAS:<p>Izuforant (JW1601) has anti-inflammatory effects, binds h5-HT3R (IC50: 9.1 μM), and blocks H4R orally (IC50: 36 nM).</p>Fórmula:C12H12BrN7Forma y color:SolidPeso molecular:334.17A-943931
CAS:<p>A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.</p>Fórmula:C17H21N5Pureza:99.79%Forma y color:SolidPeso molecular:295.38Pitolisant oxalate
CAS:<p>Pitolisant oxalate is a potent and selective inverse agonist of nonimidazole at the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>Fórmula:C19H28ClNO5Pureza:98%Forma y color:SolidPeso molecular:385.88
