Receptor de opioides
Los receptores opioides son un grupo de receptores acoplados a proteínas G que median los efectos de los opioides endógenos y exógenos. Estos receptores desempeñan un papel central en la modulación del dolor, la regulación del estado de ánimo y los comportamientos adictivos. Los agonistas y antagonistas de los receptores opioides se utilizan ampliamente en el manejo del dolor y el tratamiento de adicciones, así como en la investigación de trastornos neurológicos y psiquiátricos. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores opioides de alta calidad para apoyar su investigación en neurobiología, manejo del dolor y terapia de adicciones.
Se han encontrado 296 productos de "Receptor de opioides"
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Ac-RYYRIK-NH2
CAS:<p>NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.</p>Fórmula:C44H70N14O9Pureza:98%Forma y color:SolidPeso molecular:939.12[DPro10] Dynorphin A (1-11)acetate,porcine
<p>[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.</p>Fórmula:C65H107N21O15Pureza:99.05%Forma y color:SoildPeso molecular:1422.7Ro 64-6198
CAS:<p>Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.</p>Fórmula:C26H31N3OPureza:98%Forma y color:SolidPeso molecular:401.54Cebranopadol hemicitrate
CAS:<p>Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.</p>Forma y color:SolidNeurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Forma y color:Odour SolidOrphanin FQ(1-11)
CAS:<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Fórmula:C49H75N15O14Pureza:98%Forma y color:SolidPeso molecular:1098.2TAN67
CAS:<p>TAN67 is the first effective selective non-peptide delta1 opioid receptor.</p>Fórmula:C23H26Br2N2OForma y color:SolidPeso molecular:506.282DAMGO (TFA)
CAS:<p>DAMGO is a selective peptide agonist of the µ-opioid receptor .</p>Fórmula:C28H36F3N5O8Pureza:98%Forma y color:SolidPeso molecular:627.61CTAP
CAS:<p>Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.</p>Fórmula:C51H69N13O11S2Pureza:98%Forma y color:White Solid/PowderPeso molecular:1104.32KOR agonist 5
<p>KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).</p>Fórmula:C38H38N2O5Forma y color:SolidPeso molecular:602.72[Nphe1]Nociceptin(1-13)NH2
CAS:<p>Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.</p>Fórmula:C61H100N22O15Pureza:98%Forma y color:SolidPeso molecular:1381.6N-Desmethyl Loperamide
CAS:<p>N-Desmethyl Loperamide is the major metabolite of loperamide. It is also used as the precusor for radiolabelled loperamide.</p>Fórmula:C28H31ClN2O2Forma y color:SolidPeso molecular:463.01SNC 80
CAS:<p>SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.</p>Fórmula:C28H39N3O2Pureza:99.65%Forma y color:SolidPeso molecular:449.63KOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Fórmula:C21H25N3Forma y color:SolidPeso molecular:319.44β-Endorphin, equine TFA
<p>β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3</p>Fórmula:C156H249F3N42O46SForma y color:SolidPeso molecular:3537.96Akuammicine
CAS:<p>Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.</p>Fórmula:C20H22N2O2Forma y color:SolidPeso molecular:322.408Nociceptin(1-7)
CAS:<p>Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia</p>Fórmula:C31H41N7O9Pureza:98%Forma y color:SolidPeso molecular:655.709[(pF)Phe4]Nociceptin(1-13)NH2
CAS:<p>Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.</p>Fórmula:C61H99FN22O15Pureza:98%Forma y color:SolidPeso molecular:1399.6Boc-ypgflt(O-tbu)
CAS:<p>Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.</p>Fórmula:C44H64N6O11Forma y color:SolidPeso molecular:853.01Herkinorin
CAS:<p>Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.</p>Fórmula:C28H30O8Forma y color:SolidPeso molecular:494.53
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