Receptor de opioides
Los receptores opioides son un grupo de receptores acoplados a proteínas G que median los efectos de los opioides endógenos y exógenos. Estos receptores desempeñan un papel central en la modulación del dolor, la regulación del estado de ánimo y los comportamientos adictivos. Los agonistas y antagonistas de los receptores opioides se utilizan ampliamente en el manejo del dolor y el tratamiento de adicciones, así como en la investigación de trastornos neurológicos y psiquiátricos. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores opioides de alta calidad para apoyar su investigación en neurobiología, manejo del dolor y terapia de adicciones.
Se han encontrado 296 productos de "Receptor de opioides"
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Apitegromab
CAS:<p>Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases including</p>Pureza:95% - 97.59% (SDS-PAGE); 99.78% (SEC-HPLC)Forma y color:LiquidBTRX-335140
CAS:<p>BTRX-335140 (CYM-53093) is a potent and selective orally active κ-opioid receptor (KOR) antagonist with antagonistic activity.Cost-effective and quality-assured.</p>Fórmula:C25H32FN5O2Pureza:98% - 99.89%Forma y color:SolidPeso molecular:453.55Samidorphan HCl
CAS:<p>Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors.</p>Fórmula:C21H27ClN2O4Pureza:96.79% - 97.85%Forma y color:SoildPeso molecular:406.9Alvimopan
CAS:<p>Alvimopan is a potent opioid antagonist targeting gut receptors to reverse opioid effects on motility.</p>Fórmula:C25H32N2O4Pureza:99.47% - 99.78%Forma y color:SolidPeso molecular:424.53Sinomenine hydrochloride
CAS:<p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>Fórmula:C19H24ClNO4Pureza:99.43%Forma y color:SolidPeso molecular:365.851CP 866087
CAS:<p>CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction.</p>Fórmula:C24H30N2O3SPureza:99.22% - 99.74%Forma y color:SolidPeso molecular:426.57ZT 52656A hydrochloride
CAS:<p>ZT 52656A is a selective agonist of kappa opioid, and used for the prevention or alleviation of pain in the eye.</p>Fórmula:C19H26ClF3N2OPureza:98.78%Forma y color:SolidPeso molecular:390.87Naltrexone hydrochloride
CAS:<p>Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.</p>Fórmula:C20H24ClNO4Pureza:98.72% - 99.65%Forma y color:White Crystalline PowderPeso molecular:377.862Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Fórmula:C15H24N2OPureza:97.16% - >99.99%Forma y color:SolidPeso molecular:248.36LY2940094
CAS:<p>LY2940094 (LY-2940094) decreases ethanol self-administration in animal models.</p>Fórmula:C22H23ClF2N4O2SPureza:99.4%Forma y color:SolidPeso molecular:480.96Moguisteine
CAS:<p>Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.</p>Fórmula:C16H21NO5SPureza:99.98%Forma y color:SolidPeso molecular:339.41Meptazinol hydrochloride
CAS:<p>Meptazinol hydrochloride (Meptazinol HCl) , a unique centrally opioid analgesic, is used as a narcotic antagonist with analgesic properties.</p>Fórmula:C15H23NO·HClPureza:99.75%Forma y color:White SolidPeso molecular:269.81Loperamide hydrochloride
CAS:<p>Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.</p>Fórmula:C29H34Cl2N2O2Pureza:99.91% - >99.99%Forma y color:Crystals Practically Insoluble In WaterPeso molecular:513.50Trimebutine maleate
CAS:<p>Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects.</p>Fórmula:C26H33NO9Pureza:99.76% - 99.98%Forma y color:White SolidPeso molecular:503.55Ro 64-6198
CAS:<p>Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.</p>Fórmula:C26H31N3OPureza:98%Forma y color:SolidPeso molecular:401.54DPDPE
CAS:<p>DPDPE is selective δ-opioid receptor agonist peptide.</p>Fórmula:C30H39N5O7S2Pureza:98%Forma y color:SolidPeso molecular:645.79Boc-ypgflt(O-tbu)
CAS:<p>Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.</p>Fórmula:C44H64N6O11Forma y color:SolidPeso molecular:853.01BAM-22P
CAS:<p>Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.</p>Fórmula:C130H184N38O31S2Pureza:98%Forma y color:SolidPeso molecular:2839.22Dermorphin Analog
<p>Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.</p>Fórmula:C44H59N11O10Pureza:98%Forma y color:SolidPeso molecular:901.43TAN67
CAS:<p>TAN67 is the first effective selective non-peptide delta1 opioid receptor.</p>Fórmula:C23H26Br2N2OForma y color:SolidPeso molecular:506.282(Rac)-SNC80
CAS:<p>(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.</p>Fórmula:C28H39N3O2Forma y color:SolidPeso molecular:449.63β-Naltrexamine dihydrochloride
CAS:<p>β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.</p>Fórmula:C20H28Cl2N2O3Pureza:95.98%Forma y color:SoildPeso molecular:415.35Axelopran
CAS:<p>Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.</p>Fórmula:C26H39N3O4Forma y color:SolidPeso molecular:457.61Nociceptin(1-7)
CAS:<p>Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia</p>Fórmula:C31H41N7O9Pureza:98%Forma y color:SolidPeso molecular:655.709Orphanin FQ(1-11)
CAS:<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Fórmula:C49H75N15O14Pureza:98%Forma y color:SolidPeso molecular:1098.2CTOP
CAS:<p>Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.</p>Fórmula:C50H67N11O11S2Pureza:98%Forma y color:SolidPeso molecular:1062.28β-Endorphin, equine TFA
<p>β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3</p>Fórmula:C156H249F3N42O46SForma y color:SolidPeso molecular:3537.96Frakefamide TFA
<p>Frakefamide TFA: potent, peripherally active μ-opioid agonist; doesn't cross blood-brain barrier.</p>Fórmula:C32H35F4N5O7Forma y color:SolidPeso molecular:677.64Ac-RYYRWK-NH2
CAS:<p>Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.</p>Fórmula:C49H69N15O9Pureza:98%Forma y color:SolidPeso molecular:1012.17[(pF)Phe4]Nociceptin(1-13)NH2
CAS:<p>Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.</p>Fórmula:C61H99FN22O15Pureza:98%Forma y color:SolidPeso molecular:1399.6Akuammicine
CAS:<p>Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.</p>Fórmula:C20H22N2O2Forma y color:SolidPeso molecular:322.408Gluten Exorphin B5
CAS:<p>Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.</p>Fórmula:C30H38N6O7Pureza:98%Forma y color:SolidPeso molecular:594.66Cebranopadol hemicitrate
CAS:<p>Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.</p>Forma y color:SolidNaldemedine
CAS:<p>Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.</p>Fórmula:C32H34N4O6Forma y color:SolidPeso molecular:570.64KOR agonist 5
<p>KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).</p>Fórmula:C38H38N2O5Forma y color:SolidPeso molecular:602.72Dermorphin
CAS:<p>Dermorphin is agonist of μ-opioid receptor (MOR) agonist.</p>Fórmula:C40H50N8O10Pureza:98.82%Forma y color:SolidPeso molecular:802.87ICI 174,864
CAS:<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Fórmula:C38H53N5O7Pureza:98%Forma y color:White SolidPeso molecular:691.87Dynorphin B (1-13)
CAS:<p>Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.</p>Fórmula:C74H115N21O17Pureza:98%Forma y color:SolidPeso molecular:1570.84Neuropeptide AF (human)
CAS:<p>Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.</p>Fórmula:C90H132N26O25Pureza:98%Forma y color:SolidPeso molecular:1978.17Biphalin TFA
CAS:<p>Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.</p>Fórmula:C46H56N10O10·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:909.00 (free base)Ac-RYYRIK-NH2
CAS:<p>NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.</p>Fórmula:C44H70N14O9Pureza:98%Forma y color:SolidPeso molecular:939.12[DPro10] Dynorphin A (1-11)acetate,porcine
<p>[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.</p>Fórmula:C65H107N21O15Pureza:99.05%Forma y color:SoildPeso molecular:1422.7PL-017
CAS:<p>μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.</p>Fórmula:C29H37N5O5Pureza:98%Forma y color:SolidPeso molecular:535.64U-54494A hydrochloride
CAS:<p>U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.</p>Fórmula:C18H25Cl3N2OForma y color:SolidPeso molecular:391.76Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Forma y color:Odour SolidKOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Fórmula:C21H25N3Forma y color:SolidPeso molecular:319.44SNC 80
CAS:<p>SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.</p>Fórmula:C28H39N3O2Pureza:99.65%Forma y color:SolidPeso molecular:449.63DAMGO (TFA)
CAS:<p>DAMGO is a selective peptide agonist of the µ-opioid receptor .</p>Fórmula:C28H36F3N5O8Pureza:98%Forma y color:SolidPeso molecular:627.61[Nphe1]Nociceptin(1-13)NH2
CAS:<p>Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.</p>Fórmula:C61H100N22O15Pureza:98%Forma y color:SolidPeso molecular:1381.6HINT1-IN-1
<p>HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).</p>Fórmula:C23H24N8O5Forma y color:SolidPeso molecular:492.49
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