Receptor de opioides
Los receptores opioides son un grupo de receptores acoplados a proteínas G que median los efectos de los opioides endógenos y exógenos. Estos receptores desempeñan un papel central en la modulación del dolor, la regulación del estado de ánimo y los comportamientos adictivos. Los agonistas y antagonistas de los receptores opioides se utilizan ampliamente en el manejo del dolor y el tratamiento de adicciones, así como en la investigación de trastornos neurológicos y psiquiátricos. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores opioides de alta calidad para apoyar su investigación en neurobiología, manejo del dolor y terapia de adicciones.
Se han encontrado 296 productos de "Receptor de opioides"
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FK 33-824
CAS:<p>FK 33-824, a stable synthetic analog of methionine enkephalin, reversible with naloxone.</p>Fórmula:C29H41N5O7SPureza:98%Forma y color:SolidPeso molecular:603.73J-113397
CAS:<p>J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).</p>Fórmula:C24H37N3O2Pureza:98%Forma y color:SolidPeso molecular:399.57BNTX
CAS:<p>BNTX (7-Benzylidenenaltrexone) is a selective δ1-opioid receptor antagonist. It competitively counteracts the antisecretory effects of DPDPE, Deltorphin 2, and DAMGO. BNTX is applicable in research focused on antinociceptive effects.</p>Fórmula:C27H27NO4Forma y color:SolidPeso molecular:429.508Mu opioid receptor antagonist 4
<p>Compound 31: Potent, selective MOR antagonist; crosses blood-brain barrier; Ki & EC50: 0.38 nM; useful for OUD research.</p>Fórmula:C25H28N2O4SForma y color:SolidPeso molecular:452.57SB-612111 hydrochloride
<p>SB-612111 is a potent ORL-1 antagonist, with high affinity (Ki: 0.33 nM) and µ-receptor activity (Ki: 57.6 nM), blocking Nociceptin-induced pain.</p>Fórmula:C24H30Cl3NOForma y color:SolidPeso molecular:454.86RX 809055AX
CAS:<p>RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.</p>Fórmula:C29H29ClN2O4Forma y color:SolidPeso molecular:505SC13
CAS:<p>SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.</p>Fórmula:C26H30N2O5Forma y color:SolidPeso molecular:450.53BU09059
CAS:<p>BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).</p>Fórmula:C28H37N3O5Pureza:98%Forma y color:SolidPeso molecular:495.61Mu opioid receptor antagonist 3
<p>Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.</p>Fórmula:C25H28N2O4SForma y color:SolidPeso molecular:452.57Allyphenyline oxalate
CAS:<p>The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.</p>Fórmula:C16H20N2O5Forma y color:SolidPeso molecular:320.34rel-SB-612111 hydrochloride
CAS:<p>NOP receptor antagonist</p>Fórmula:C24H30Cl3NOPureza:98%Forma y color:SolidPeso molecular:454.86Naldemedine tosylate
CAS:<p>Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.</p>Fórmula:C39H42N4O9SForma y color:SolidPeso molecular:742.84(S)-MCOPPB
CAS:<p>(S)-MCOPPB is the S-enantiomer of MCOPPB, an orally active selective agonist for the Nociceptin/Orphanin FQ-Receptor. It inhibits signal transduction in mouse brain NOP receptors and is utilized in anxiety disorder research.</p>Fórmula:C26H40N4Forma y color:SolidPeso molecular:408.623Opioid receptor antagonist 1
CAS:<p>Opioid receptor antagonist 1 (Compound 10) is an Orvinol-based antagonist of opioid receptors. It exhibits activity as an antagonist against the analgesic properties of morphine.</p>Fórmula:C24H29ClF3NO4Forma y color:SolidPeso molecular:487.94Naltrindole 5′-isothiocyanate
CAS:<p>Naltrindole 5′-isothiocyanate (5'-NTII) is an irreversible delta opioid receptor antagonist that counters the analgesic effects induced by DSLET without altering the effects caused by DPDPE.</p>Fórmula:C27H25N3O3SForma y color:SolidPeso molecular:471.571Bromadoline
CAS:<p>Bromadoline is an opioid compound that exhibits anti-nociceptive properties in rodents.</p>Fórmula:C15H21BrN2OForma y color:SolidPeso molecular:325.244KNT-127
CAS:<p>KNT-127 is an agonist of δ-Opioid receptor.</p>Fórmula:C24H24N2O2Pureza:98%Forma y color:SolidPeso molecular:372.46(±)-J 113397
CAS:<p>(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).</p>Fórmula:C24H37N3O2Forma y color:SolidPeso molecular:399.575′-Guanidinonaltrindole
CAS:<p>5′-Guanidinonaltrindole (GNTI) is a selective antagonist of the kappa opioid receptor.</p>Fórmula:C27H29N5O3Forma y color:SolidPeso molecular:471.551GNTI dihydrochloride
CAS:<p>κ opioid receptor antagonist</p>Fórmula:C27H30ClN5O3Pureza:98%Forma y color:SolidPeso molecular:508.01Sunobinop
CAS:<p>Sunobinop (S 117957) is an opioid receptor-like orphan receptor (ORL1) modulator.</p>Fórmula:C26H33N3O3Forma y color:SolidPeso molecular:435.56σ1 Receptor/μ Opioid receptor modulator 2
CAS:<p>Compound 4x, also known as σ1 Receptor/μOpioid receptormodulator 2, acts as a μOR agonist and a σ1R antagonist, exhibiting a potent μOR EC50 of 0.6 nM and strong σ1R inhibitory activity (Ki: 363.7 nM). It demonstrates significant analgesic effects in various pain models.</p>Fórmula:C23H31N3OPeso molecular:365.51Norbinaltorphimine dihydrochloride
CAS:<p>Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.</p>Fórmula:C40H45Cl2N3O6Pureza:98.17% - 99.88%Forma y color:SolidPeso molecular:734.71BU72
CAS:<p>BU72 is a potent, long-lasting agonist for μ and κ opioid receptors, with partial agonistic activity at the δ opioid receptor (EC50 values of 0.054, 0.033, and 0.58 nM, respectively). It provides strong, enduring analgesic effects primarily mediated through μ opioid receptors. BU72 also exhibits a prolonged duration of activity and can partially reverse morphine-induced analgesia. It is applicable in studies of opioid dependence.</p>Fórmula:C28H32N2O2Forma y color:SolidPeso molecular:428.57Riminkefon
CAS:<p>Riminkefon is a kappa opioid receptor agonist .</p>Fórmula:C38H57N7O6Forma y color:SolidPeso molecular:707.9JDTic Dihydrochloride
CAS:<p>JDTic Dihydrochloride is a high-affinity and selective κ-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling,antidepressant.</p>Fórmula:C28H41Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:538.55Mu opioid receptor antagonist 8
CAS:<p>Muopioid Receptor Antagonist 8 (368) serves as an antagonist to the μ-opioid receptor, significantly inhibiting the activation of Gi induced by met-enkephalin at the µOR.</p>Fórmula:C36H35N3O4SForma y color:SolidPeso molecular:605.756β-Naltrexol
CAS:<p>6β-Naltrexol is a peripherally selective opioid antagonist that reduces constipation from opioids while minimizing central nervous system effects.</p>Fórmula:C20H25NO4Pureza:99.933%Forma y color:SolidPeso molecular:343.42DS34942424
<p>DS34942424 is an orally potent analgesic which did not exhibit mu opioid receptor agonist activity.</p>Fórmula:C15H17FN2OForma y color:SolidPeso molecular:260.31Mu opioid receptor antagonist 5
<p>Compound NAP: MOR antagonist, crosses blood-brain barrier, EC50: 1.14 nM, Ki: 0.37 nM, useful for OUD research.</p>Fórmula:C26H29N3O4Forma y color:SolidPeso molecular:447.53BW 443C
CAS:<p>BW 443C is a selective agonist of mu-opioid receptor.</p>Fórmula:C33H46N10O10Forma y color:SolidPeso molecular:742.791Mu opioid receptor antagonist 2
<p>Compound 25: potent, selective MOR antagonist, crosses blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM), for OUD research.</p>Fórmula:C25H28N2O4SForma y color:SolidPeso molecular:452.57SB-612111
CAS:<p>SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.</p>Fórmula:C24H29Cl2NOForma y color:SolidPeso molecular:418.40Isotodesnitazene
CAS:<p>Isotodesnitazene is an opioid compound that primarily targets the μ-opioid receptor (MOR). It exhibits EC50 values of 34.8 nM and 142 nM for MOR-βarr2 and MOR-mini-Gi, respectively. Isotodesnitazene can be utilized for research in opioid drugs.</p>Fórmula:C23H31N3OForma y color:SolidPeso molecular:365.51Anilopam
CAS:<p>Anilopam is an opioid analgesic belonging to the benzazepine class and acts as an agonist at opioid receptors.</p>Fórmula:C20H26N2OForma y color:SolidPeso molecular:310.4322-Thiocyanatosalvinorin A
CAS:<p>22-Thiocyanatosalvinorin A (RB-64) is a potent selective agonist for the kappa-opioid receptor, exhibiting an EC50 value of 0.077 nM.</p>Fórmula:C24H27NO8SForma y color:SolidPeso molecular:489.54CCG258747
CAS:<p>CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.</p>Fórmula:C28H27FN4O4Forma y color:SolidPeso molecular:502.54BNTX maleate
CAS:<p>δ1 opioid receptor antagonist</p>Fórmula:C31H31NO8Pureza:98%Forma y color:SolidPeso molecular:545.58Daeatal
CAS:<p>Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.</p>Fórmula:C56H93N19O10Pureza:98%Forma y color:SolidPeso molecular:1192.46Nalmefene
CAS:<p>Nalmefene (ORF 11676) is a μ-opioid antagonist and partial κ agonist used in the study of opioid overdose and alcohol dependence.</p>Fórmula:C21H25NO3Pureza:99.86%Forma y color:SolidPeso molecular:339.43Propiram fumarate HCl
CAS:<p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>Fórmula:C16H25N3O·xClHPureza:99.25%Forma y color:SoildSR17018
CAS:<p>SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.</p>Fórmula:C19H18Cl3N3OPureza:99.89%Forma y color:SolidPeso molecular:410.72Cebranopadol
CAS:<p>Cebranopadol (GRT6005) is an analgesic NOP and opioid receptor agonist with Kis of 0.9 nM, 0.7 nM, 2.6 nM, 18 nM for human NOP, μ-opioid (MOP), κ-opioid (KOP)</p>Fórmula:C24H27FN2OPureza:98.32% - 99.78%Forma y color:SolidPeso molecular:378.48Bromadoline maleate
CAS:<p>Bromadoline is an opioid analgesic selective for the μ-opioid receptor.</p>Fórmula:C19H25BrN2O5Pureza:98%Forma y color:SolidPeso molecular:441.322SR14150
CAS:<p>SR14150 is a partial agonist of high-affinity NOP receptor.</p>Fórmula:C21H30N2OPureza:98%Forma y color:SolidPeso molecular:326.48MOR agonist-1
CAS:<p>MOR Agonist-1 is a μ-opioid receptor (MOR) agonist noted for its potent analgesic properties and is utilized in research concerning pain and associated</p>Fórmula:C22H26ClFN2O2Pureza:98%Forma y color:SolidPeso molecular:404.91
