Receptor de opioides
Los receptores opioides son un grupo de receptores acoplados a proteínas G que median los efectos de los opioides endógenos y exógenos. Estos receptores desempeñan un papel central en la modulación del dolor, la regulación del estado de ánimo y los comportamientos adictivos. Los agonistas y antagonistas de los receptores opioides se utilizan ampliamente en el manejo del dolor y el tratamiento de adicciones, así como en la investigación de trastornos neurológicos y psiquiátricos. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores opioides de alta calidad para apoyar su investigación en neurobiología, manejo del dolor y terapia de adicciones.
Se han encontrado 332 productos para "Receptor de opioides".
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RX 809055AX
CAS:RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.Fórmula:C29H29ClN2O4Forma y color:SolidPeso molecular:505MOR agonist-5
CAS:MOR agonist-5 is a selective and potent μ-opioid receptor (MOR) agonist with an EC50 of 0.25 nM. It exhibits an EC50 of 10 nM at δ-opioid receptors (DOR), while its EC50 at κ-opioid receptors (KOR) and nociceptin receptors (NOR) is greater than 10000 nM. MOR agonist-5 demonstrates significant antinociceptive activity and is useful for pain-related research.Fórmula:C22H27N3OPeso molecular:349.48SC13
CAS:SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.Fórmula:C26H30N2O5Forma y color:SolidPeso molecular:450.53BU09059
CAS:BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).Fórmula:C28H37N3O5Pureza:98%Forma y color:SolidPeso molecular:495.61Mu opioid receptor antagonist 3
Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.Fórmula:C25H28N2O4SForma y color:SolidPeso molecular:452.57Sameridine
CAS:Sameridine (NIH-10908) acts as a weak partial agonist at the μ-opioid receptor. When administered intrathecally, it induces local anesthesia and analgesia. At low doses, Sameridine minimally affects respiratory function, but higher doses can suppress respiratory response. It is useful for research into analgesic effects.Fórmula:C21H34N2OPeso molecular:330.52Allyphenyline oxalate
CAS:The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.Fórmula:C16H20N2O5Forma y color:SolidPeso molecular:320.34rel-SB-612111 hydrochloride
CAS:NOP receptor antagonistFórmula:C24H30Cl3NOPureza:98%Forma y color:SolidPeso molecular:454.86Naldemedine tosylate
CAS:Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.Fórmula:C39H42N4O9SForma y color:SolidPeso molecular:742.84U-54494A hydrochloride
CAS:U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.Fórmula:C18H25Cl3N2OForma y color:SolidPeso molecular:391.76Tramadol N-oxide
CAS:Tramadol N-oxide (T-N-O) (RWJ 38705) is an analgesic. In animal models such as the mouse abdominal constriction test, 48°C and 55°C hot plate tests, and the tail-flick assay, Tramadol N-oxide demonstrates a dose-dependent and prolonged analgesic effect. Its affinity for opioid μ receptors (Ki = 38.5 μM) and δ or κ receptors (Ki > 100 μM) is negligible. Tramadol N-oxide is used for researching analgesic effects.Fórmula:C16H25NO3Peso molecular:279.38Ro 64-6198
CAS:Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Fórmula:C26H31N3OPureza:98%Forma y color:SolidPeso molecular:401.54
