SGLT
Los cotransportadores sodio-glucosa (SGLT) son proteínas de membrana que facilitan la reabsorción de glucosa en los riñones al acoplar el transporte de glucosa con los iones de sodio. Los inhibidores de SGLT son una clase importante de medicamentos utilizados en el tratamiento de la diabetes tipo 2, ya que ayudan a reducir los niveles de glucosa en sangre al prevenir la reabsorción de glucosa en los túbulos renales. Estos inhibidores también están siendo investigados por sus posibles beneficios en la protección cardiovascular y renal. En CymitQuimica, ofrecemos una gama de moduladores de SGLT de alta calidad para apoyar su investigación en diabetes, fisiología renal y trastornos metabólicos.
Se han encontrado 31 productos de "SGLT"
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KGA-2727
CAS:KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.Fórmula:C26H40N4O8Pureza:98.46%Forma y color:SolidPeso molecular:536.62Ref: TM-T15656
1mg109,00€2mg158,00€5mg260,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€1mL*10mM (DMSO)305,00€Sergliflozin A
CAS:Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.Fórmula:C20H24O7Pureza:99.71%Forma y color:SolidPeso molecular:376.4O-Desethyl Dapagliflozin
CAS:O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.Fórmula:C19H21ClO6Pureza:98.33%Forma y color:SolidPeso molecular:380.82Ref: TM-T67849
1mg54,00€5mg114,00€10mg177,00€25mg304,00€50mg445,00€100mg647,00€1mL*10mM (DMSO)128,00€Canagliflozin (Standard)
CAS:Canagliflozin (Standard) is the standard substance of Canagliflozin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM).Fórmula:C24H25FO5SForma y color:SolidPeso molecular:444.52Sotagliflozin
CAS:Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potentialFórmula:C21H25ClO5SPureza:99% - 99.86%Forma y color:SolidPeso molecular:424.94Ref: TM-T3547
1mg46,00€2mg57,00€5mg87,00€10mg131,00€25mg248,00€50mg378,00€100mg560,00€500mg1.198,00€1mL*10mM (DMSO)88,00€Empagliflozin
CAS:Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6.Fórmula:C23H27ClO7Pureza:98% - 99.98%Forma y color:SolidPeso molecular:450.91Ref: TM-T1766
1g278,00€5mg47,00€10mg60,00€50mg79,00€100mg96,00€200mg144,00€500mg188,00€1mL*10mM (DMSO)50,00€Mizagliflozin
CAS:Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1.Cost-effective and quality-assured.Fórmula:C28H44N4O8Pureza:98.66% - 99.67%Forma y color:SolidPeso molecular:564.67Ref: TM-T16083
1mg66,00€2mg96,00€5mg144,00€10mg227,00€25mg455,00€50mg645,00€100mg938,00€200mg1.264,00€1mL*10mM (DMSO)173,00€Dapagliflozin
CAS:Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Fórmula:C21H25ClO6Pureza:99.5% - 99.93%Forma y color:SolidPeso molecular:408.87Ref: TM-T2389
5mg47,00€10mg60,00€25mg77,00€50mg94,00€100mg107,00€200mg142,00€1500mg284,00€1mL*10mM (DMSO)52,00€Enavogliflozin
CAS:Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.Fórmula:C24H27ClO6Pureza:97.37%Forma y color:SolidPeso molecular:446.92Ref: TM-T38843
1mg147,00€5mg358,00€10mg560,00€25mg973,00€50mg1.333,00€100mg1.765,00€1mL*10mM (DMSO)394,00€Ipragliflozin
CAS:Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
Fórmula:C21H21FO5SPureza:99.38% - 99.70%Forma y color:SolidPeso molecular:404.45T-1095
CAS:T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Fórmula:C26H28O11Pureza:99.78%Forma y color:SolidPeso molecular:516.49Ref: TM-T9590
1mg50,00€2mg71,00€5mg90,00€10mg130,00€25mg207,00€50mg370,00€100mg530,00€1mL*10mM (DMSO)127,00€Phloretin
CAS:Phloretin (NSC-407292) inhibits eukaryotic urea transporters, has antioxidative properties, and can induce cancer cell apoptosis. Found in apples and apricots.
Fórmula:C15H14O5Pureza:98.53% - >99.99%Forma y color:SolidPeso molecular:274.27Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-Fórmula:C24H35ClO9Pureza:99.88% - 99.94%Forma y color:SolidPeso molecular:502.98Canagliflozin
CAS:Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.Fórmula:C24H25FO5SPureza:98.01% - >99.99%Forma y color:SolidPeso molecular:444.52Ref: TM-T1782
2mg35,00€5mg50,00€10mg66,00€25mg87,00€50mg96,00€100mg123,00€500mg274,00€1mL*10mM (DMSO)52,00€Phlorizin
CAS:Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
Fórmula:C21H24O10Pureza:99.73% - 99.77%Forma y color:Solid CrystallinePeso molecular:436.41Tofogliflozin (hydrate)
CAS:Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(Ki of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).Fórmula:C22H28O7Pureza:97.03% - 98.78%Forma y color:SolidPeso molecular:404.45Ref: TM-T5016
1mg35,00€2mg49,00€5mg74,00€10mg109,00€25mg202,00€50mg324,00€100mg505,00€200mg717,00€1mL*10mM (DMSO)82,00€Ertugliflozin
CAS:PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).Fórmula:C22H25ClO7Pureza:99.89% - 99.96%Forma y color:SolidPeso molecular:436.88Bexagliflozin
CAS:Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2.Fórmula:C24H29ClO7Pureza:98.99% - 99.89%Forma y color:SolidPeso molecular:464.94Ref: TM-T7217
1mg67,00€2mg95,00€5mg129,00€10mg187,00€25mg371,00€50mg552,00€100mg785,00€1mL*10mM (DMSO)137,00€Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFórmula:C21H24O10Pureza:97.16%Forma y color:SolidPeso molecular:436.41Ref: TM-T2S0731
1mg50,00€5mg99,00€10mg141,00€25mg260,00€50mg385,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)109,00€Canagliflozin hemihydrate
CAS:Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.Fórmula:C48H52F2O11S2Pureza:99.42% - 99.96%Forma y color:SolidPeso molecular:907.05
