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Receptor de glucagón

Receptor de glucagón

Los receptores de glucagón son GPCR que median los efectos del glucagón, una hormona involucrada en la regulación de la homeostasis de la glucosa al promover la descomposición del glucógeno y la liberación de glucosa desde el hígado. Estos receptores son cruciales en la gestión de los niveles de azúcar en sangre y son de particular interés en el estudio de la diabetes y los trastornos metabólicos. Los antagonistas de los receptores de glucagón se están explorando como posibles tratamientos para la hiperglucemia en la diabetes tipo 2. En CymitQuimica, ofrecemos una variedad de moduladores de receptores de glucagón de alta calidad para apoyar su investigación en endocrinología, diabetes y regulación metabólica.

Se han encontrado 164 productos de "Receptor de glucagón"

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  • [Des-His1,Glu9]-Glucagon amide

    CAS:
    <p>Glucagon blocker with pA2 of 7.2; no agonist effect. Boosts insulin; prevents glucagon-driven hyperglycemia in rabbits and diabetic rats.</p>
    Fórmula:C148H221N41O47S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3358.68
  • GLP-1R agonist 27


    <p>GLP-1R agonist 27 (compound 21) is a potent and orally active GLP-1R agonist. It enhances the accumulation of cyclic adenosine monophosphate (cAMP), reduces blood glucose levels, and decreases food intake. GLP-1R agonist 27 shows potential for research in obesity and type 2 diabetes mellitus (T2DM).</p>
    Fórmula:C32H33N5O4Se
    Forma y color:Solid
    Peso molecular:630.6
  • (S)-V-0219 hydrochloride


    <p>(S)-V-0219 hydrochloride, a GLP-1R PAM, triggers calcium in hGLP-1R HEK cells, lowers glucose in mice, and reduces fasting hunger.</p>
    Fórmula:C20H26ClF3N4O2
    Forma y color:Solid
    Peso molecular:446.89
  • GLP-1R agonist 15

    CAS:
    <p>GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .</p>
    Fórmula:C46H47FN8O7S
    Forma y color:Solid
    Peso molecular:874.98
  • Gulgafafusp alfa

    CAS:
    <p>Gulgafafusp alfa is a human IgG2κ monoclonal antibody that selectively binds to the glucagon-like peptide 1 receptor (GLP1R) [1].</p>
    Forma y color:Liquid
  • Anti-GLP-1R Antibody


    <p>Anti-GLP-1R Antibody is an anti-GLP-1R antibody that can be used for immunohistochemistry of paraffin sections.</p>
    Pureza:98.3% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.3% (SDS-PAGE); 97.2% (SEC-HPLC)
    Forma y color:Odour Liquid
  • SPN009


    <p>SPN009 (Sequence 3) is a GLP-1 receptor (GLP-1 Receptor) agonist, with an EC50 of 2.84 nM, and improves type 2 diabetes in DB/DB mouse models.</p>
    Fórmula:C191H299N45O59
    Peso molecular:4167.17798
  • Glucagon-like peptide 1 (1-37), human TFA


    <p>Human Glucagon-like peptide 1 (1-37) TFA is a potent GLP-1 receptor agonist derived from proglucagon.</p>
    Fórmula:C188H276N51F3O61
    Pureza:98%
    Forma y color:Solid
    Peso molecular:4283.5
  • GLP-1R agonist 20


    <p>GLP-1R agonist 20 (Compound I-132) is an agonist of the glucagon-like peptide-1 receptor (GLP-1 receptor), with an EC50 value of 0.0162 nM.</p>
    Fórmula:C31H30Cl2F2N4O5
    Peso molecular:646.15613
  • GLP-1R agonist 16

    CAS:
    <p>Compound 115a, a GLP-1R agonist, effectively activates the GLP-1 receptor with an EC50 of 0.15 nM [1].</p>
    Fórmula:C50H58FN10O6P
    Forma y color:Solid
    Peso molecular:945.03
  • GLP-1R agonist 4

    CAS:
    <p>GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.</p>
    Fórmula:C32H30ClF2N3O5
    Forma y color:Solid
    Peso molecular:610.05
  • SAR441255


    <p>SAR441255 is a potent unimolecular peptide that acts as a GLP-1/GIP/GCG receptor triagonist, demonstrating balanced activation across all three target receptors</p>
    Forma y color:Odour Solid
  • FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS


    <p>FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.</p>
    Forma y color:Solid
    Peso molecular:3692.15
  • Dapiglutide

    CAS:
    <p>Dapiglutide (ZP7570) is a long-acting GLP-1R &amp; GLP-2R dual agonist for SBS research.</p>
    Forma y color:Solid
  • GRPP (human)

    CAS:
    <p>GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations.</p>
    Fórmula:C136H215N41O58S
    Forma y color:Solid
    Peso molecular:3384.47
  • Glucagon (1-29), bovine, human, porcine

    CAS:
    <p>Corynoxine B (Cory B) is a naturally occurring alkaloid isolated from Uncaria rhynchophylla (Miq. ) and is an autophagy inducer.</p>
    Fórmula:C153H225N43O49S
    Pureza:99.56% - 99.56%
    Forma y color:Solid
    Peso molecular:3482.75
  • GLP-1 receptor agonist 7

    CAS:
    <p>GLP-1 receptor agonist 7, potential for diabetes research, from patent WO2021219019A1.</p>
    Fórmula:C31H30ClFN4O5
    Forma y color:Solid
    Peso molecular:593.05
  • GLP-1 receptor agonist 2

    CAS:
    <p>GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>
    Fórmula:C30H31ClFN5O4
    Forma y color:Solid
    Peso molecular:580.05
  • V-0219

    CAS:
    <p>V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.</p>
    Fórmula:C20H25F3N4O2
    Pureza:99.91%
    Forma y color:Soild
    Peso molecular:410.43
  • GLP-1R modulator C16

    CAS:
    <p>GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.</p>
    Fórmula:C21H26ClFN2O3
    Pureza:99.6% - >99.99%
    Forma y color:Solid
    Peso molecular:408.89