Receptor de glucagón
Los receptores de glucagón son GPCR que median los efectos del glucagón, una hormona involucrada en la regulación de la homeostasis de la glucosa al promover la descomposición del glucógeno y la liberación de glucosa desde el hígado. Estos receptores son cruciales en la gestión de los niveles de azúcar en sangre y son de particular interés en el estudio de la diabetes y los trastornos metabólicos. Los antagonistas de los receptores de glucagón se están explorando como posibles tratamientos para la hiperglucemia en la diabetes tipo 2. En CymitQuimica, ofrecemos una variedad de moduladores de receptores de glucagón de alta calidad para apoyar su investigación en endocrinología, diabetes y regulación metabólica.
Se han encontrado 197 productos para "Receptor de glucagón".
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Liraglutide
CAS:Liraglutide (Liraglutida) is a synthetic analog of GLP-1, an agonist of the GLP-1 receptor. Liraglutide is an antidiabetic agent. Cost effective and quality assured.Fórmula:C172H265N43O51Pureza:97.65% - 99.04%Forma y color:White SolidPeso molecular:3751.25Teduglutide acetate
Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy.Fórmula:C166H256N44O56SPureza:97.39%Forma y color:SolidPeso molecular:3812.13NNC-0640
CAS:NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.Fórmula:C29H31N7O4SPureza:97.04%Forma y color:SolidPeso molecular:573.67Ref: TM-T7364
1mg46,00€2mg62,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg160,00€25mg281,00€50mg430,00€100mg620,00€Gulgafafusp alfa
CAS:Gulgafafusp alfa is a human antibody that specifically targets GLP-1R.Forma y color:LiquidGLP-1 Receptor modulator 1
CAS:GLP-1 Receptormodulator 1 (Compound 7) is an effective positive allosteric modulator of the GLP-1 receptor. It is utilized in the research of obesity and type 2 diabetes.Fórmula:C18H21NOSPeso molecular:299.43PF-06412154 HCl
CAS:PF-06412154 HCl is a glucagon receptor antagonist.Fórmula:C24H28ClN3O3Forma y color:SolidPeso molecular:441.96Glucagon receptor antagonists-2
CAS:Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist.Fórmula:C22H30FNO2Pureza:98%Forma y color:SolidPeso molecular:359.48GLP-1R agonist 1
CAS:GLP-1R agonist 1, an imidazole derivative and potent GLP-1R activator, may aid diabetes research.Fórmula:C32H29ClFN3O5Forma y color:SolidPeso molecular:590.04(S)-V-0219
(S)-V-0219: oral, GLP-1R PAM, boosts calcium in hGLP-1R HEK cells, lowers glucose, curbs hunger in mice.Fórmula:C20H25F3N4O2Forma y color:SolidPeso molecular:410.43Glucagon receptor antagonists-5
CAS:Oral indazole-based glucagon antagonist, Ki: 32 nM, may treat type 2 diabetes.Fórmula:C30H29ClF3N3O3Pureza:98%Forma y color:SolidPeso molecular:572.02Efpeglenatide
CAS:Efpeglenatide is a long-acting GLP-1 receptor agonist that improves insulin sensitivity, lowers blood glucose, delays weight gain, and supports metabolic disease research.Pureza:100% - 100%Forma y color:Yellow SolidGCGR antagonist 2
CAS:Orally active GCGR antagonist 2, a furan-2-carbohydrazide, binds hGluR at 2.3 nM. Blocks glucagon, inhibits rat receptor at 0.43 nM.Fórmula:C28H26N4O2Forma y color:SolidPeso molecular:450.53MS012
CAS:MS012 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase (Kd = 46 ± 15 nM).Fórmula:C22H35N5O2Forma y color:SolidPeso molecular:401.55BAY-27-9955
CAS:BAY-27-9955 is a glucagon receptor antagonist.Fórmula:C23H31FOForma y color:SolidPeso molecular:342.49(R)-V-0219
(R)-V-0219: GLP-1R PAM, orally active, triggers Ca++ flux in HEK-hGLP-1R cells.Fórmula:C20H25F3N4O2Forma y color:SolidPeso molecular:410.43L-168049
CAS:L-168049: Human glucagon receptor antagonist, IC50 - 3.7 nM human, 63 nM murine, 60 nM canine.Fórmula:C24H20BrClN2OPureza:>99.99%Forma y color:SolidPeso molecular:467.79NNC 92-1687
CAS:NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.Fórmula:C15H12N2O3SPureza:98.70% - 99.96%Forma y color:SolidPeso molecular:300.33Glucagon receptor antagonists-3
CAS:Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.Fórmula:C22H30FNO2Pureza:98%Forma y color:SolidPeso molecular:359.48GLP-1R agonist 3
CAS:GLP-1R agonist 3 is a GLP-1R agonist, an imidazole derivative.GLP-1R agonist 3 can be used to study diabetes and obesity.Fórmula:C31H28FN5O4Pureza:97.19%Forma y color:Yellow SolidPeso molecular:553.58LGD-6972 sodium
CAS:LGD-6972 sodium is a glucagon receptor antagonist.Fórmula:C43H46N2NaO5SPureza:98%Forma y color:SolidPeso molecular:725.9GLP-1R agonist 12
CAS:GLP-1R agonist 12 (Compound 123) 是一种 GLP-1R 激动剂，能够用于研究糖尿病。Fórmula:C34H36N6O4Forma y color:SolidPeso molecular:592.69GLP-1R agonist 17
CAS:GLP-1R agonist 17 excels in stimulating GLP-1 receptors, useful for cardiovascular metabolic disease research.Fórmula:C28H26ClFN4O4SForma y color:SolidPeso molecular:569.05Retagliptin hydrochloride
CAS:Retagliptin (SP2086) hydrochloride serves as a potent inhibitor of dipeptidyl peptidase-4 (DPP-4) and beta-amino acids. This compound aids in the management of type 2 diabetes and enhances glycemic control by extending the activity of intestinal hormones, notably glucagon-like peptide-1 (GLP-1) .Fórmula:C19H19ClF6N4O3Forma y color:SolidPeso molecular:500.82GLP-1R agonist 9
CAS:GLP-1R agonist 9 acts as a GLP-1R agonist, demonstrating efficacy with EC50 values of 1.1 nM and 11 nM against CHO GLP-1R Clone H6 and Clone C6, respectively.Fórmula:C32H30ClF2N3O5Forma y color:SolidPeso molecular:610.05GLP-1R agonist 10
CAS:GLP-1R agonist 10 is a GLP-1 agonist (EC50: 0.051 nM).Fórmula:C29H29ClFN5O4Forma y color:SolidPeso molecular:566.02MK3577
CAS:MK3577 is a glucagon receptor antagonist.Fórmula:C30H30ClFN2O3Forma y color:SolidPeso molecular:521.02MK 0893
CAS:MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist competitive, reversible cAMP activity, which attenuates blood glucose elevation.Fórmula:C32H27Cl2N3O4Pureza:98.79%Forma y color:Yellow SolidPeso molecular:588.48Antitumor agent-101
CAS:Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM forFórmula:C26H38N6O3Pureza:98%Forma y color:SolidPeso molecular:482.62GLP-1 receptor agonist 3
CAS:GLP-1 receptor agonist 3 is a GLP-1 receptor agonist,Example 4A-1, has EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively.Fórmula:C31H30FN5O4Pureza:98%Forma y color:SolidPeso molecular:555.6Lotiglipron
CAS:Lotiglipron (PF-07081532) is a GLP-1R agonist that lowers blood glucose and may be used in the study of type 2 diabetes mellitus (T2DM) and excess obesity.Fórmula:C31H31ClN4O5Pureza:98.3%Forma y color:SolidPeso molecular:575.05Ref: TM-T77781
1mg66,00€5mg133,00€1mL*10mM (DMSO)170,00€10mg197,00€25mg394,00€50mg512,00€100mg670,00€Adomeglivant
CAS:Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.Fórmula:C32H36F3NO4Pureza:99.51%Forma y color:SolidPeso molecular:555.63LGD-6972
CAS:LGD-6972 is an antagonist of glucagon receptor.Fórmula:C43H46N2O5SPureza:98.8% - 99.62%Forma y color:SolidPeso molecular:702.9Ref: TM-T11845
1mg84,00€5mg177,00€10mg260,00€1mL*10mM (DMSO)268,00€25mg447,00€50mg655,00€100mg888,00€GLP-1 receptor agonist 10
CAS:GLP-1 Receptor Agonist 10 (Compound 42), an agonist of the GLP receptor, reduces glucose excursions and inhibits food intake in mice. It is useful for research into type 2 diabetes (T2DM) and obesity [1].Fórmula:C30H28F4N6O5Forma y color:SolidPeso molecular:628.57GLP-1 receptor agonist 11
CAS:GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].Fórmula:C31H31ClFN3O4Forma y color:SolidPeso molecular:564.05LXT34
CAS:LXT34 (Example 2) is a GPR120 agonist with anti-inflammatory properties. This compound enhances GLP-1 formation in the gastrointestinal tract and improves insulin resistance in macrophages and pancreatic cells. LXT34 is applicable in studies related to inflammatory conditions, such as type 2 diabetes, obesity, and non-alcoholic fatty liver disease.Fórmula:C18H21NO3SForma y color:SolidPeso molecular:331.43GLP-1R modulator-1
CAS:GLP-1R modulator-1 (Compound 384) is a potent and orally active selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). It activates G protein-coupled signaling, leading to increased intracellular cAMP levels, enhanced insulin secretion, delayed gastric emptying, and reduced appetite. GLP-1R modulator-1 holds potential for research in type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).Fórmula:C41H38ClFN6O4Forma y color:SolidPeso molecular:733.23GLP-1R agonist 8
CAS:GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).Fórmula:C33H32N4O5Forma y color:SolidPeso molecular:564.63PF-06372222
CAS:PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.Fórmula:C26H28F3N5O3Pureza:98%Forma y color:SolidPeso molecular:515.53GLP-1R agonist 32
CAS:GLP-1R agonist 32 (Compound 111) is an orally active and potent GLP-1R agonist with an EC50 value of 0.017 nM. It stimulates the production of cyclic adenosine monophosphate (cAMP) by activating GLP-1R, which enhances insulin secretion, suppresses glucagon release, and delays gastric emptying to regulate blood glucose levels. GLP-1R agonist 32 shows potential for research in type 2 diabetes, obesity, and related metabolic disorders.Fórmula:C32H31ClFN3O5Forma y color:SolidPeso molecular:592.06GLP-1 receptor agonist 16
CAS:GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.Fórmula:C33H31ClFN3O4Forma y color:SolidPeso molecular:588.068DA-302168S
CAS:DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.Fórmula:C33H24ClF2N3O5Forma y color:SolidPeso molecular:616.011GLP-1 receptor agonist 12
CAS:Compound 20A, known as GLP-1 receptor agonist 12, acts as an agonist of the GLP receptor. It is utilized in researching diseases like diabetes [1].Fórmula:C31H31FN6O4Forma y color:SolidPeso molecular:570.61SCH-900822
CAS:SCH-900822 is a potent and selective glucagon receptor antagonist.Fórmula:C34H43Cl2N7O2Forma y color:SolidPeso molecular:652.66DS79932728
CAS:DS79932728 is an orally active inhibitor of G9a and GLP, with IC50 values of 12.6 nM and 75.7 nM, respectively. It induces the production of γ-globin, thereby increasing fetal hemoglobin (HbF) levels. In cynomolgus monkey models, DS79932728 enhances the proportion of F-reticulocytes (F-rets) and shows good oral absorption characteristics.Fórmula:C19H25N3OForma y color:SolidPeso molecular:311.421GLP-1R agonist 33
CAS:GLP-1R agonist 33 (Compound 224) is a GLP-1 receptor agonist with potential applications in research related to diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).Fórmula:C30H27FN6O4Forma y color:SolidPeso molecular:554.57GLP-1 receptor agonist 15
CAS:GLP-1 receptor agonist 15 (Example 4) is a GLP receptor agonist with an EC50 of 0.74 nM. It exhibits an IC50 of 10.1 μM against the hERG potassium ion channel. This compound is applicable for research in the diabetes field.Fórmula:C32H31ClFN3O5Forma y color:SolidPeso molecular:592.057LSN3318839
CAS:LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and canFórmula:C26H23Cl2N3O2Pureza:99.70%Forma y color:SolidPeso molecular:480.39
