Receptor de glucagón
Los receptores de glucagón son GPCR que median los efectos del glucagón, una hormona involucrada en la regulación de la homeostasis de la glucosa al promover la descomposición del glucógeno y la liberación de glucosa desde el hígado. Estos receptores son cruciales en la gestión de los niveles de azúcar en sangre y son de particular interés en el estudio de la diabetes y los trastornos metabólicos. Los antagonistas de los receptores de glucagón se están explorando como posibles tratamientos para la hiperglucemia en la diabetes tipo 2. En CymitQuimica, ofrecemos una variedad de moduladores de receptores de glucagón de alta calidad para apoyar su investigación en endocrinología, diabetes y regulación metabólica.
Se han encontrado 196 productos de "Receptor de glucagón"
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GLP-1R agonist 33
CAS:GLP-1R agonist 33 (Compound 224) is a GLP-1 receptor agonist with potential applications in research related to diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).Fórmula:C30H27FN6O4Forma y color:SolidPeso molecular:554.57SCH-900822
CAS:SCH-900822 is a potent and selective glucagon receptor antagonist.Fórmula:C34H43Cl2N7O2Forma y color:SolidPeso molecular:652.66DA-302168S
CAS:<p>DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.</p>Fórmula:C33H24ClF2N3O5Forma y color:SolidPeso molecular:616.011GLP-1R agonist 8
CAS:GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).Fórmula:C33H32N4O5Forma y color:SolidPeso molecular:564.63DS79932728
CAS:DS79932728 is an orally active inhibitor of G9a and GLP, with IC50 values of 12.6 nM and 75.7 nM, respectively. It induces the production of γ-globin, thereby increasing fetal hemoglobin (HbF) levels. In cynomolgus monkey models, DS79932728 enhances the proportion of F-reticulocytes (F-rets) and shows good oral absorption characteristics.Fórmula:C19H25N3OForma y color:SolidPeso molecular:311.421GLP-1 receptor agonist 16
CAS:GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.Fórmula:C33H31ClFN3O4Forma y color:SolidPeso molecular:588.068PF-06372222
CAS:<p>PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.</p>Fórmula:C26H28F3N5O3Pureza:98%Forma y color:SolidPeso molecular:515.53GLP-1R modulator-1
CAS:GLP-1R modulator-1 (Compound 384) is a potent and orally active selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). It activates G protein-coupled signaling, leading to increased intracellular cAMP levels, enhanced insulin secretion, delayed gastric emptying, and reduced appetite. GLP-1R modulator-1 holds potential for research in type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).Fórmula:C41H38ClFN6O4Forma y color:SolidPeso molecular:733.23GLP-1 receptor agonist 15
CAS:GLP-1 receptor agonist 15 (Example 4) is a GLP receptor agonist with an EC50 of 0.74 nM. It exhibits an IC50 of 10.1 μM against the hERG potassium ion channel. This compound is applicable for research in the diabetes field.Fórmula:C32H31ClFN3O5Forma y color:SolidPeso molecular:592.057GLP-1 receptor agonist 10
CAS:GLP-1 Receptor Agonist 10 (Compound 42), an agonist of the GLP receptor, reduces glucose excursions and inhibits food intake in mice. It is useful for research into type 2 diabetes (T2DM) and obesity [1].Fórmula:C30H28F4N6O5Peso molecular:628.57LXT34
CAS:LXT34 (Example 2) is a GPR120 agonist with anti-inflammatory properties. This compound enhances GLP-1 formation in the gastrointestinal tract and improves insulin resistance in macrophages and pancreatic cells. LXT34 is applicable in studies related to inflammatory conditions, such as type 2 diabetes, obesity, and non-alcoholic fatty liver disease.Fórmula:C18H21NO3SForma y color:SolidPeso molecular:331.43GLP-1 receptor agonist 11
CAS:GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].Fórmula:C31H31ClFN3O4Forma y color:SolidPeso molecular:564.05GLP-1R agonist 32
CAS:GLP-1R agonist 32 (Compound 111) is an orally active and potent GLP-1R agonist with an EC50 value of 0.017 nM. It stimulates the production of cyclic adenosine monophosphate (cAMP) by activating GLP-1R, which enhances insulin secretion, suppresses glucagon release, and delays gastric emptying to regulate blood glucose levels. GLP-1R agonist 32 shows potential for research in type 2 diabetes, obesity, and related metabolic disorders.Fórmula:C32H31ClFN3O5Forma y color:SolidPeso molecular:592.06GLP-1 receptor agonist 12
CAS:Compound 20A, known as GLP-1 receptor agonist 12, acts as an agonist of the GLP receptor. It is utilized in researching diseases like diabetes [1].Fórmula:C31H31FN6O4Peso molecular:570.61LSN3318839
CAS:<p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>Fórmula:C26H23Cl2N3O2Pureza:99.21%Forma y color:SolidPeso molecular:480.39Anti-GLP1R Antibody
<p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>Forma y color:Odour Liquid
