Receptor LPA
Los receptores de ácido lisofosfatídico (LPA) son un grupo de GPCR que responden al LPA, un lípido bioactivo involucrado en la proliferación, migración y supervivencia celular. La señalización de LPA juega un papel crucial en varios procesos fisiológicos, incluyendo la cicatrización de heridas, el desarrollo vascular y la metástasis del cáncer. La modulación de la actividad de los receptores de LPA se está explorando para aplicaciones terapéuticas en el cáncer, la fibrosis y las enfermedades inflamatorias. En CymitQuimica, ofrecemos una gama de moduladores de receptores de LPA de alta calidad para apoyar su investigación en señalización celular, oncología y trastornos inflamatorios.
Se han encontrado 21 productos de "Receptor LPA"
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AM095 free acid
CAS:AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1).Fórmula:C27H24N2O5Pureza:99.88%Forma y color:SolidPeso molecular:456.49Ref: TM-T10293
1mg35,00€5mg66,00€10mg97,00€25mg180,00€50mg283,00€100mg439,00€200mg660,00€1mL*10mM (DMSO)73,00€Ki16198
CAS:Ki16198, a methyl ester derivative of Ki16425, blocks LPA1/3, weak on LPA2; inactive on LPA4/5/6. Ki values: 0.34 μM (LPA1), 0.93 μM (LPA3).Fórmula:C24H25ClN2O5SPureza:98.09%Forma y color:SolidPeso molecular:488.98ACT-1016-0707
CAS:ACT-1016-0707 is a selective, insurmountable LPA1 antagonist with antifibrotic and anti-inflammatory activity in lung fibrosis modelsFórmula:C19H23ClN4O4SPureza:99.905%Forma y color:SolidPeso molecular:438.93TAK-615
CAS:TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.Fórmula:C25H22FNO4Pureza:99.73%Forma y color:SolidPeso molecular:419.44Ref: TM-T9699
1mg75,00€5mg169,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€500mg1.624,00€1mL*10mM (DMSO)180,00€Edg-2 receptor inhibitor 1
CAS:Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).Fórmula:C27H27NO5Pureza:99.47%Forma y color:SolidPeso molecular:445.51Ref: TM-T4521
1mg97,00€2mg170,00€5mg274,00€10mg426,00€25mg663,00€50mg947,00€100mg1.264,00€1mL*10mM (DMSO)288,00€BMS-986020 sodium
CAS:BMS-986020 sodium (AM152 sodium) is a high-affinity LPA1 antagonist for investigating idiopathic pulmonary fibrosis.Fórmula:C29H25N2NaO5Pureza:99.83%Forma y color:SolidPeso molecular:504.51H2L 5765834
CAS:H2L 5765834 is a lysophosphatidic acid receptors antagonistFórmula:C21H12N2O7Pureza:98.25% - 99.47%Forma y color:SolidPeso molecular:404.33Ref: TM-T22834
1mg62,00€5mg119,00€10mg187,00€25mg354,00€50mg525,00€100mg747,00€1mL*10mM (DMSO)131,00€ONO-7300243
CAS:ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).Fórmula:C28H31NO5Pureza:99.66%Forma y color:SolidPeso molecular:461.55Ki16425
CAS:Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.Fórmula:C23H23ClN2O5SPureza:97.6% - 97.78%Forma y color:SolidPeso molecular:474.96Tetradecyl Phosphonate
CAS:Tetradecyl Phosphonate 是溶血磷脂酸 1 (LPA1)、LPA2 和 LPA3 受体的泛拮抗剂。Fórmula:C14H31O3PPureza:99.95%Forma y color:White To Off-White PowderPeso molecular:278.37AM095
CAS:AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.Fórmula:C27H23N2NaO5Pureza:98.87%Forma y color:SolidPeso molecular:478.47Ref: TM-T2000
1mg35,00€2mg47,00€5mg66,00€10mg97,00€25mg180,00€50mg283,00€100mg439,00€1mL*10mM (DMSO)70,00€AM966
CAS:<p>AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.</p>Fórmula:C27H23ClN2O5Pureza:98.06% - 99.79%Forma y color:SolidPeso molecular:490.93BMS-986020
CAS:BMS-986020 (AM152) is a selective antagonist of LPA1.Fórmula:C29H26N2O5Pureza:98.82% - >99.99%Forma y color:SolidPeso molecular:482.531-Oleoyl lysophosphatidic acid sodium
CAS:1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2Fórmula:C21H40O7P·NaPureza:98.75% - 99.24%Forma y color:SolidPeso molecular:458.51Ref: TM-T21654
1mg40,00€2mg52,00€5mg85,00€10mg137,00€25mg283,00€50mg494,00€100mg727,00€200mg1.017,00€BMS-986278
CAS:<p>BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1,</p>Fórmula:C22H31N5O5Pureza:99.86%Forma y color:SolidPeso molecular:445.51Radioprotectin-1
CAS:Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.Fórmula:C23H19ClN2O6SPureza:98.63% - 99.27%Forma y color:SolidPeso molecular:486.92Ref: TM-T12684
1mg81,00€5mg170,00€10mg259,00€25mg425,00€50mg562,00€100mg775,00€1mL*10mM (DMSO)187,00€LPA2 antagonist 2
CAS:LPA2 antagonist 2 is an and LPA2 antagonist (IC50: 28.3 nM) with potential anticancer activity, inhibits LPA3, and can be used for cancer research.Fórmula:C20H16N2O6Pureza:96.13%Forma y color:SolidPeso molecular:380.35LPA2 antagonist 1
CAS:LPA2 antagonist 1 is a potent LPA2 antagonist.Fórmula:C20H23Cl2N5O2S2Pureza:99.85%Forma y color:SolidPeso molecular:500.47TC LPA5 4
CAS:TC LPA5 4 is a LPA5 receptor antagonist.Fórmula:C23H23ClN2O3Pureza:99.93%Forma y color:SolidPeso molecular:410.89Ref: TM-T23438
1mg52,00€5mg103,00€10mg165,00€25mg341,00€50mg512,00€100mg753,00€200mg1.035,00€1mL*10mM (DMSO)113,00€LPA1 receptor antagonist 1
CAS:LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a lysophosphatidic acid receptor antagonist for the study of idiopathic pulmonary fibrosis.Fórmula:C28H26N4O4Pureza:99.46% - 99.56%Forma y color:SolidPeso molecular:482.53
