Receptor LPA
Los receptores de ácido lisofosfatídico (LPA) son un grupo de GPCR que responden al LPA, un lípido bioactivo involucrado en la proliferación, migración y supervivencia celular. La señalización de LPA juega un papel crucial en varios procesos fisiológicos, incluyendo la cicatrización de heridas, el desarrollo vascular y la metástasis del cáncer. La modulación de la actividad de los receptores de LPA se está explorando para aplicaciones terapéuticas en el cáncer, la fibrosis y las enfermedades inflamatorias. En CymitQuimica, ofrecemos una gama de moduladores de receptores de LPA de alta calidad para apoyar su investigación en señalización celular, oncología y trastornos inflamatorios.
Se han encontrado 21 productos para "Receptor LPA".
Filtrar por
Porcentaje de pureza
0
100
|
0
|
50
|
90
|
95
|
100
- Precio más bajo
- Precio más alto
- Pureza más baja
- Pureza más alta
- Entrega estimada más rápida
AM095 free acid
CAS:AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1).Fórmula:C27H24N2O5Pureza:99.88%Forma y color:SolidPeso molecular:456.49Ref: TM-T10293
1mg34,00€5mg63,00€1mL*10mM (DMSO)70,00€10mg92,00€25mg170,00€50mg268,00€100mg416,00€200mg625,00€Edg-2 receptor inhibitor 1
CAS:Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).Fórmula:C27H27NO5Pureza:99.47%Forma y color:SolidPeso molecular:445.507Ref: TM-T4521
1mg92,00€2mg166,00€5mg259,00€1mL*10mM (DMSO)273,00€10mg404,00€25mg628,00€50mg897,00€100mg1.198,00€TAK-615
CAS:TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.Fórmula:C25H22FNO4Pureza:99.73%Forma y color:SolidPeso molecular:419.4449Ref: TM-T9699
1mg72,00€5mg160,00€1mL*10mM (DMSO)172,00€10mg245,00€25mg405,00€50mg572,00€100mg772,00€500mg1.539,00€ACT-1016-0707
CAS:ACT-1016-0707 is a selective, insurmountable LPA1 antagonist with antifibrotic and anti-inflammatory activity in lung fibrosis modelsFórmula:C19H23ClN4O4SPureza:99.90%Forma y color:White SolidPeso molecular:438.93Ki16198
CAS:Ki16198, a methyl ester derivative of Ki16425, blocks LPA1/3, weak on LPA2; inactive on LPA4/5/6. Ki values: 0.34 μM (LPA1), 0.93 μM (LPA3).Fórmula:C24H25ClN2O5SPureza:98.09%Forma y color:SolidPeso molecular:488.98BMS-986020 sodium
CAS:BMS-986020 sodium (AM152 sodium) is a high-affinity LPA1 antagonist for investigating idiopathic pulmonary fibrosis.Fórmula:C29H25N2NaO5Pureza:99.83%Forma y color:White SolidPeso molecular:504.51Tetradecyl Phosphonate
CAS:Tetradecyl Phosphonate 是溶血磷脂酸 1 (LPA1)、LPA2 和 LPA3 受体的泛拮抗剂。Fórmula:C14H31O3PPureza:99.95%Forma y color:SolidPeso molecular:278.3679AM966
CAS:AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.Fórmula:C27H23ClN2O5Pureza:98.06% - 99.79%Forma y color:White SolidPeso molecular:490.935ONO-7300243
CAS:ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).Fórmula:C28H31NO5Pureza:99.66%Forma y color:SolidPeso molecular:461.5494BMS-986020
CAS:BMS-986020 (AM152) is a selective antagonist of LPA1.Fórmula:C29H26N2O5Pureza:98.82% - >99.99%Forma y color:SolidPeso molecular:482.53AM095
CAS:AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.Fórmula:C27H23N2NaO5Pureza:97.05% - 99.71%Forma y color:SolidPeso molecular:478.4717Ref: TM-T2000
1mg34,00€2mg44,00€5mg63,00€1mL*10mM (DMSO)66,00€10mg92,00€25mg170,00€50mg268,00€100mg416,00€H2L 5765834
CAS:H2L 5765834 is a lysophosphatidic acid receptors antagonistFórmula:C21H12N2O7Pureza:98.25% - 99.47%Forma y color:SolidPeso molecular:404.3292Ref: TM-T22834
1mg58,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg334,00€50mg497,00€100mg708,00€Ki16425
CAS:Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.Fórmula:C23H23ClN2O5SPureza:97.6% - 97.78%Forma y color:White SolidPeso molecular:474.96BMS-986278
CAS:BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1,Fórmula:C22H31N5O5Pureza:99.83% - 99.88%Forma y color:White SolidPeso molecular:445.51Radioprotectin-1
CAS:Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.Fórmula:C23H19ClN2O6SPureza:98.63% - 99.27%Forma y color:White SolidPeso molecular:486.92Ref: TM-T12684
1mg77,00€5mg166,00€1mL*10mM (DMSO)177,00€10mg245,00€25mg404,00€50mg532,00€100mg735,00€LPA2 antagonist 1
CAS:LPA2 antagonist 1 is a potent LPA2 antagonist.Fórmula:C20H23Cl2N5O2S2Pureza:99.85%Forma y color:SolidPeso molecular:500.47LPA2 antagonist 2
CAS:LPA2 antagonist 2 is an and LPA2 antagonist (IC50: 28.3 nM) with potential anticancer activity, inhibits LPA3, and can be used for cancer research.Fórmula:C20H16N2O6Pureza:99.29%Forma y color:SolidPeso molecular:380.3508Ref: TM-T11875
1mg60,00€5mg133,00€1mL*10mM (DMSO)138,00€10mg205,00€25mg339,00€50mg477,00€100mg642,00€TC LPA5 4
CAS:TC LPA5 4 is a LPA5 receptor antagonist.Fórmula:C23H23ClN2O3Pureza:99.93%Forma y color:SolidPeso molecular:410.89Ref: TM-T23438
1mg49,00€5mg98,00€1mL*10mM (DMSO)107,00€10mg157,00€25mg324,00€50mg485,00€100mg713,00€200mg982,00€ASP6432
CAS:ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.Fórmula:C26H32KN4O6S2Forma y color:SolidPeso molecular:599.78LPA1 receptor antagonist 1
CAS:LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a lysophosphatidic acid receptor antagonist for the study of idiopathic pulmonary fibrosis.Fórmula:C28H26N4O4Pureza:99.56% - 99.87%Forma y color:SolidPeso molecular:482.53
